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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
bisantrene 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
376
78186-34-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
bisantrene dihydrochloride
bisantrene hydrochloride
bisantrene
Molecular weight: 398.47
Formula: C22H22N8
CLOGP: 2.11
LIPINSKI: 0
HAC: 8
HDO: 4
TPSA: 97.56
ALOGS: -4.18
ROTB: 4
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
CHEBI has role
CHEBI:35610
antineoplastic agents
MeSH PA
D000903
Antibiotics, Antineoplastic
MeSH PA
D000970
Antineoplastic Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
9.53
Basic
pKa2
8.92
Basic
pKa3
5.15
Basic
pKa4
4.55
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
NAD(P)H dehydrogenase [quinone] 1
Enzyme
P15559
NQO1_HUMAN
IC50
4.60
CHEMBL
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External reference:
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ID
Source
39C34M111K
UNII
5131
INN_ID
5351322
PUBCHEM_CID
71439-68-4
SECONDARY_CAS_RN
C0053776
UMLSCUI
C031404
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:88337
CHEBI
CHEMBL139554
ChEMBL_ID
CHEMBL1979684
ChEMBL_ID
CHEMBL25336
ChEMBL_ID
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Pharmaceutical products:
None
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Structure 🔎
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bisantrene