bisantrene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
376 78186-34-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bisantrene dihydrochloride
  • bisantrene hydrochloride
  • bisantrene
  • Molecular weight: 398.47
  • Formula: C22H22N8
  • CLOGP: 2.11
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 4
  • TPSA: 97.56
  • ALOGS: -4.18
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000903 Antibiotics, Antineoplastic
MeSH PA D000970 Antineoplastic Agents
CHEBI has role CHEBI:35610 antineoplastic agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.53 Basic
pKa2 8.92 Basic
pKa3 5.15 Basic
pKa4 4.55 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
NAD(P)H dehydrogenase [quinone] 1 Enzyme IC50 4.60 CHEMBL

External reference:

IDSource
71439-68-4 SECONDARY_CAS_RN
C0053776 UMLSCUI
CHEBI:88337 CHEBI
CHEMBL25336 ChEMBL_ID
CHEMBL139554 ChEMBL_ID
CHEMBL3989424 ChEMBL_ID
CHEMBL1979684 ChEMBL_ID
C031404 MESH_SUPPLEMENTAL_RECORD_UI
5351322 PUBCHEM_CID
5131 INN_ID
39C34M111K UNII

Pharmaceutical products:

None