diperodon 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
local anaesthetics	3734	537-12-2

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

diperodon hydrochloride
diothane hydrochloride
diperodon
diperodon HCl
diothane HCl

Molecular weight: 397.48
Formula: C22H27N3O4
CLOGP: 4.30
LIPINSKI: 0
HAC: 7
HDO: 2
TPSA: 79.90
ALOGS: -3.66
ROTB: 9

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	10.95	acidic
pKa2	11.67	acidic
pKa3	6.64	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Sodium channel alpha subunits; brain (Types I, II, III)	Ion channel	P35498 Q99250 Q9NY46	SCN1A_HUMAN SCN2A_HUMAN SCN3A_HUMAN		IC50	5.89		CHEMBL

External reference:

ID	Source
4018890	VUID
N0000147184	NUI
4018890	VANDF
4019723	VANDF
C0163518	UMLSCUI
CHEBI:93842	CHEBI
POW	PDB_CHEM_ID
CHEMBL338667	ChEMBL_ID
CHEMBL2109119	ChEMBL_ID
DB11513	DRUGBANK_ID
C027013	MESH_SUPPLEMENTAL_RECORD_UI
10831	PUBCHEM_CID
133043	RXNORM
4610	MMSL
7426	MMSL
001364	NDDF
005114	NDDF
373495000	SNOMEDCT_US
44175000	SNOMEDCT_US
96267003	SNOMEDCT_US
5YZ5R8I73Y	UNII

Pharmaceutical products:

None