acedapsone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antimycobacterials, diaminodiphenylsulfone derivatives 3662 77-46-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acedapsone
  • acetamin
  • diacetyldapsone
  • sulfadiamine
  • sulfodiamin
  • sulfodiamine
Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent.
  • Molecular weight: 332.37
  • Formula: C16H16N2O4S
  • CLOGP: 1.30
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 92.34
  • ALOGS: -3.38
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000962 Antimalarials
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000981 Antiprotozoal Agents
MeSH PA D007917 Leprostatic Agents
CHEBI has role CHEBI:36043 antimicrobial drugs
CHEBI has role CHEBI:38068 antimalarials

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.09 acidic
pKa2 13.7 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02751 KEGG_DRUG
C0000949 UMLSCUI
CHEBI:139474 CHEBI
CHEMBL154166 ChEMBL_ID
D000072 MESH_DESCRIPTOR_UI
6477 PUBCHEM_CID
2719 INN_ID
0GZ72U84TN UNII

Pharmaceutical products:

None