thyropropic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3604 51-26-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • thyropropic acid
  • atralose
  • birodan
  • triopron
  • triprop
  • Molecular weight: 635.96
  • Formula: C15H11I3O4
  • CLOGP: 5.79
  • LIPINSKI: 2
  • HAC: 4
  • HDO: 2
  • TPSA: 66.76
  • ALOGS: -5.27
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.31 acidic
pKa2 8.29 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Thyroid hormone receptor alpha Nuclear hormone receptor IC50 10.39 CHEMBL
Thyroid hormone receptor beta Nuclear hormone receptor IC50 10.72 CHEMBL
Proliferating cell nuclear antigen Nuclear other IC50 4.77 CHEMBL

External reference:

IDSource
C4726847 UMLSCUI
CHEBI:135860 CHEBI
CHEMBL291053 ChEMBL_ID
904 INN_ID
OK7481S22O UNII
5804 PUBCHEM_CID

Pharmaceutical products:

None