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sulisobenzone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 3572 | 4065-45-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AURKC,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,CSF1R,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GRK3,GSK3B,IGF1R,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,KIT,MAP2K6,MAP3K1,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAP4K3,MAPK1,MAPK10,MAPK12,MAPK14,MAPK7,MAPK8,MAPK9,MAPKAPK2,MAPKAPK5,MARK4,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKCD,PRKDC,SGK1,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ULK2,ZAP70 | 76 | |||
| kinase-selectivity-class | ACVR2A,AXL,BRAF,CDK9,DDR1,DYRK1B,EPHB4,ERBB2,GRK2,MAP2K6,MAPK12,MAPK7,PRKDC,SIK2,STK33,SYK,TEK,TTK,ZAP70 | 19 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Sunscreen agent | indication | 49663007 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.05 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D05964 | KEGG_DRUG |
| 4020448 | VANDF |
| C0075618 | UMLSCUI |
| CHEBI:135312 | CHEBI |
| I4Y | PDB_CHEM_ID |
| CHEMBL2059073 | ChEMBL_ID |
| DB11185 | DRUGBANK_ID |
| C009361 | MESH_SUPPLEMENTAL_RECORD_UI |
| 19988 | PUBCHEM_CID |
| 2098 | INN_ID |
| 1W6L629B4K | UNII |
| 1311567 | RXNORM |
| 001972 | NDDF |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Rayito de Sol | HUMAN OTC DRUG LABEL | 2 | 20367-132 | GEL | 4 g | TOPICAL | OTC monograph final | 14 sections |
| Rayito de Sol | HUMAN OTC DRUG LABEL | 2 | 20367-133 | GEL | 4 g | TOPICAL | OTC monograph final | 13 sections |
| anti-frizz sheets | HUMAN OTC DRUG LABEL | 1 | 47993-240 | SWAB | 2 g | TOPICAL | OTC monograph not final | 7 sections |
| Brillie Ultimate Soothing Sun Shield | HUMAN OTC DRUG LABEL | 2 | 80134-050 | CREAM | 1.50 g | TOPICAL | OTC monograph not final | 1 sections |