selenomethionine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3544 3211-76-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • selenomethionine
  • vitaselenium
  • selenomax
  • L-Selenomethionine
Diagnostic aid in pancreas function determination.
  • Molecular weight: 196.12
  • Formula: C5H11NO2Se
  • CLOGP: -1.89
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 63.32
  • ALOGS: -0.25
  • ROTB: 4
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AXL,BRAF,BTK,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,ITK,JAK2,JAK3,KDR,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIM2,PLK1,PRKDC,SIK2,STK33,SYK,TEK,TGFBR1,ZAP70 42
kinase-selectivity-class ACVR2B,AXL,BRAF,CDK9,EIF2AK3,EPHB4,GRK2,MAP2K6,MAP3K14,MAPK7,STK33,TEK,TGFBR1 13
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Obstructive defaecation 74.86 65.53 10 688 260 90627489
Stoma site dermatitis 74.28 65.53 10 688 276 90627473
Gastrointestinal stoma output abnormal 70.44 65.53 10 688 410 90627339

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Obstructive defaecation 77.38 72.05 10 672 252 110588365
Stoma site dermatitis 76.06 72.05 10 672 289 110588328
Gastrointestinal stoma output abnormal 72.38 72.05 10 672 422 110588195

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:76924 plant metabolite

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.47 acidic
pKa2 9.92 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000006108 NUI
C0036584 UMLSCUI
MSE PDB_CHEM_ID
CHEMBL113178 ChEMBL_ID
DB11142 DRUGBANK_ID
D012645 MESH_DESCRIPTOR_UI
15103 PUBCHEM_CID
964MRK2PEL UNII
9644 RXNORM
34847 MMSL
009044 NDDF
710051007 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
BACMIN HUMAN PRESCRIPTION DRUG LABEL 19 0682-3001 TABLET, COATED 50 ug ORAL UNAPPROVED DRUG OTHER 10 sections
Vital-D Rx HUMAN PRESCRIPTION DRUG LABEL 13 59528-1988 TABLET, COATED 70 ug ORAL unapproved drug other 4 sections
Viva CT Prenatal HUMAN PRESCRIPTION DRUG LABEL 12 64661-811 TABLET, CHEWABLE 50 ug ORAL UNAPPROVED DRUG OTHER 16 sections