phenoxyethanol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3442 122-99-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • 2-phenoxyethanol
  • (2-Hydroxyethoxy)benzene
  • ethylene glycol monophenyl ether
  • phenoxethol
  • phenoxyethyl alcohol
  • phenoxyethanol
  • Molecular weight: 138.17
  • Formula: C8H10O2
  • CLOGP: 1.19
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 29.46
  • ALOGS: -0.76
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,JAK2,MAP3K21,MAP3K7,MAPK7,NTRK2,PDK2,PDK4,PIK3CB,PRKDC,SIK2,SIK3,TEK 28
kinase-selectivity-class AXL,BRAF,ERBB2,GRK2,PDK4 5
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Appendicolith 100.04 90.05 32 1647 13424 42606232
Myasthenia gravis 90.41 90.05 31 1648 16106 42603550
Appendicitis 90.38 90.05 33 1646 20580 42599076

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Appendicolith 128.75 86.48 32 1629 14223 110573415
Appendicitis 111.18 86.48 33 1628 28431 110559207
Myasthenia gravis 111.09 86.48 31 1630 21480 110566158
Blood phosphorus increased 105.11 86.48 28 1633 16312 110571326
Hyperphosphataemia 95.62 86.48 26 1635 16355 110571283
Ventricular fibrillation 95.09 86.48 32 1629 41281 110546357
Blood uric acid increased 93.01 86.48 27 1634 21502 110566136

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000777 Anesthetics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
CHEBI has role CHEBI:35441 antiinfective agent
CHEBI has role CHEBI:35488 central nervous system depressant

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Antiseptic preparation indication 261276004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D08359 KEGG_DRUG
CHEBI:64275 CHEBI
268 PDB_CHEM_ID
CHEMBL1229846 ChEMBL_ID
C005398 MESH_SUPPLEMENTAL_RECORD_UI
DB11304 DRUGBANK_ID
89552 RXNORM
NOCODE MMSL
003752 NDDF
424614001 SNOMEDCT_US
84103009 SNOMEDCT_US
C0301042 UMLSCUI
31236 PUBCHEM_CID
HIE492ZZ3T UNII
HIE492ZZ3T INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Sanitary alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41425-001 CLOTH 0.45 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-002 CLOTH 0.45 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-003 CLOTH 0.06 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-004 CLOTH 0.28 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-006 CLOTH 0.50 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-007 CLOTH 0.50 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-008 CLOTH 7.40 g EXTRACORPOREAL OTC monograph not final 7 sections
ALCOHOL WIPES HUMAN OTC DRUG LABEL 5 41546-009 CLOTH 0.60 g EXTRACORPOREAL OTC monograph not final 8 sections
DISINFECTING ALCOHOL WIPES HUMAN OTC DRUG LABEL 5 41546-010 CLOTH 0.65 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol wipes HUMAN OTC DRUG LABEL 5 41546-012 CLOTH 0.50 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-013 CLOTH 0.45 g TOPICAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-014 CLOTH 0.06 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-015 CLOTH 0.50 g EXTRACORPOREAL OTC monograph not final 7 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-016 CLOTH 0.50 g TOPICAL OTC monograph not final 9 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-017 CLOTH 0.50 g TOPICAL OTC monograph not final 8 sections
Alcohol disinfectant wipes HUMAN OTC DRUG LABEL 5 41546-018 CLOTH 7.40 g TOPICAL OTC monograph not final 8 sections
ALCOHOL WIPES HUMAN OTC DRUG LABEL 5 41546-022 CLOTH 0.60 g EXTRACORPOREAL OTC monograph not final 8 sections
DISINFECTING ALCOHOL WIPES HUMAN OTC DRUG LABEL 5 41546-023 CLOTH 0.65 g EXTRACORPOREAL OTC monograph not final 7 sections
Disinfection Wet Wipes HUMAN OTC DRUG LABEL 2 42003-101 PATCH 0.50 U TOPICAL OTC monograph not final 12 sections
CPAP WIPES HUMAN OTC DRUG LABEL 1 43116-031 CLOTH 0.30 g CUTANEOUS unapproved drug other 12 sections
Disinfecting Wipes HUMAN OTC DRUG LABEL 6 55485-003 CLOTH 0.60 g EXTRACORPOREAL unapproved drug other 7 sections
Disinfectant Cleaning Wipes HUMAN OTC DRUG LABEL 6 55485-004 CLOTH 0.60 g EXTRACORPOREAL unapproved drug other 7 sections
Aiweier Alcohol Wipes HUMAN OTC DRUG LABEL 5 55490-004 CLOTH 0.19 g TOPICAL OTC monograph not final 7 sections
MANUGEL 85 HUMAN OTC DRUG LABEL 2 62169-202 GEL 0.30 g TOPICAL OTC monograph not final 11 sections
Sanitize/Disinfect Wipes HUMAN OTC DRUG LABEL 9 69733-100 CLOTH 0.20 1 TOPICAL OTC monograph not final 13 sections
Sanitize/Disinfect Wipes HUMAN OTC DRUG LABEL 9 69733-200 CLOTH 0.20 1 TOPICAL OTC monograph not final 13 sections
Sanitize/Disinfect Wipes HUMAN OTC DRUG LABEL 9 69733-300 CLOTH 0.20 1 TOPICAL OTC monograph not final 13 sections
Disinfect Wipes HUMAN OTC DRUG LABEL 9 69733-400 CLOTH 0.20 1 TOPICAL OTC monograph not final 13 sections
Disinfect Wipes HUMAN OTC DRUG LABEL 9 69733-500 CLOTH 0.20 1 TOPICAL OTC monograph not final 13 sections
Disinfect Wipes HUMAN OTC DRUG LABEL 9 69733-600 CLOTH 0.20 1 TOPICAL OTC monograph not final 13 sections