phenadoxone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3435 467-84-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • phenadoxone
  • heptazone
  • morphodone
  • phenodoxone
  • phenadoxone hydrochloride
  • phenadoxone HCl
  • Molecular weight: 351.49
  • Formula: C23H29NO2
  • CLOGP: 3.88
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 0
  • TPSA: 29.54
  • ALOGS: -4.87
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,CAMK2B,CAMK2D,CDK5,CDK9,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,MAP3K7,MAPK10,MAPK7,NTRK2,PDK2,PDK4,PIK3CB,PRKDC,TEK 21
kinase-selectivity-class AXL,FLT3,GRK2,PDK4,SIK2,SIK3,STK33 7
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.73 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C1882360 UMLSCUI
CHEBI:135484 CHEBI
CHEMBL2104551 ChEMBL_ID
10089 PUBCHEM_CID
4168 INN_ID
545-91-5 SECONDARY_CAS_RN
375W3TA42N UNII

Pharmaceutical products:

None