phenacaine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
local anaesthetics 3434 101-93-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • phenacaine
  • fenacaine
  • holocaine
  • tanicaine
  • Molecular weight: 298.39
  • Formula: C18H22N2O2
  • CLOGP: 5.16
  • LIPINSKI: 1
  • HAC: 4
  • HDO: 1
  • TPSA: 42.85
  • ALOGS: -4.81
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.08 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Sodium channel alpha subunits; brain (Types I, II, III) Ion channel IC50 5.77 CHEMBL

External reference:

IDSource
C0301293 UMLSCUI
CHEBI:135260 CHEBI
CHEMBL127123 ChEMBL_ID
7588 PUBCHEM_CID
254 INN_ID
V3M4D317W8 UNII
004859 NDDF
111135004 SNOMEDCT_US

Pharmaceutical products:

None