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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
phenacaine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
local anaesthetics
3434
101-93-9
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
phenacaine
fenacaine
holocaine
tanicaine
Molecular weight: 298.39
Formula: C18H22N2O2
CLOGP: 5.16
LIPINSKI: 1
HAC: 4
HDO: 1
TPSA: 42.85
ALOGS: -4.81
ROTB: 6
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
9.08
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Sodium channel alpha subunits; brain (Types I, II, III)
Ion channel
P35498
Q99250
Q9NY46
SCN1A_HUMAN
SCN2A_HUMAN
SCN3A_HUMAN
IC50
5.77
CHEMBL
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External reference:
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ID
Source
004859
NDDF
111135004
SNOMEDCT_US
254
INN_ID
7588
PUBCHEM_CID
C0301293
UMLSCUI
CHEBI:135260
CHEBI
CHEMBL127123
ChEMBL_ID
V3M4D317W8
UNII
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Pharmaceutical products:
None
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Structure 🔎
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phenacaine