benzylhydrochlorothiazide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
336 1824-50-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • benzylhydrochlorothiazide
  • benclortriazide
  • benzclortriazide
  • behyd
thiazide diuretic used as a blood pressure-lowering agent
  • Molecular weight: 387.85
  • Formula: C14H14ClN3O4S2
  • CLOGP: 1.57
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 118.36
  • ALOGS: -3.34
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypertensive disorder indication 38341003 DOID:10763
Congestive heart failure indication 42343007 DOID:6000
Malignant hypertension indication 70272006 DOID:10824




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.84 acidic
pKa2 10.95 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01246 KEGG_DRUG
C0621906 UMLSCUI
CHEBI:31269 CHEBI
CHEMBL1562084 ChEMBL_ID
C042169 MESH_SUPPLEMENTAL_RECORD_UI
2348 PUBCHEM_CID
176437APQH UNII
008191 NDDF

Pharmaceutical products:

None