leteprinim 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
nootropic agents, purine derivatives 3318 138117-50-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • leteprinim potassium
  • leteprinim
a neuroprotective agent that has been shown to improve memory; induces NGF-dependent nociceptive nerve sprouting
  • Molecular weight: 327.30
  • Formula: C15H13N5O4
  • CLOGP: -0.25
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 3
  • TPSA: 125.68
  • ALOGS: -2.68
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.27 acidic
pKa2 9.16 acidic
pKa3 13.7 acidic
pKa4 2.57 Basic
pKa5 1.55 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04698 KEGG_DRUG
192564-13-9 SECONDARY_CAS_RN
C2825404 UMLSCUI
CHEBI:135395 CHEBI
CHEMBL2104345 ChEMBL_ID
CHEMBL2146108 ChEMBL_ID
C086241 MESH_SUPPLEMENTAL_RECORD_UI
135409548 PUBCHEM_CID
7814 INN_ID
NBY3IU407M UNII

Pharmaceutical products:

None