furtrethonium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
quaternary ammonium compounds 3256 7618-86-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • furtrethonium chloride
  • furmethide
  • furtrethonium
  • furfuryltrimethylammonium
  • furtretonium
  • furtrimethonium
  • furtrethonium iodide
  • Molecular weight: 140.21
  • Formula: C8H14NO
  • CLOGP: -3.26
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 0
  • TPSA: 13.14
  • ALOGS: -3.65
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D018678 Cholinergic Agents
MeSH PA D018679 Cholinergic Agonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Muscarinic acetylcholine receptor M1 GPCR AGONIST Ki 4.10 IUPHAR
Muscarinic acetylcholine receptor M2 GPCR AGONIST Ki 4.50 IUPHAR
Muscarinic acetylcholine receptor M3 GPCR AGONIST Ki 4.10 IUPHAR
Muscarinic acetylcholine receptor M4 GPCR AGONIST Ki 4.30 IUPHAR

External reference:

IDSource
6035-90-1 SECONDARY_CAS_RN
541-64-0 SECONDARY_CAS_RN
C0060876 UMLSCUI
CHEBI:134764 CHEBI
CHEMBL2110739 ChEMBL_ID
10938 PUBCHEM_CID
C028530 MESH_SUPPLEMENTAL_RECORD_UI
299 IUPHAR_LIGAND_ID
AIQ630U6XO UNII
CHEMBL2105806 ChEMBL_ID
133 INN_ID

Pharmaceutical products:

None