eseridine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
acetylcholinesterase inhibitors	3186	25573-43-7

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

eseridine tartrate
eseridine salicylate
eserine oxide salicylate
eseridine
geneserine
eserine aminoxide
eserine oxide
physostigmine aminoxide

Molecular weight: 291.35
Formula: C15H21N3O3
CLOGP: 2.17
LIPINSKI: 0
HAC: 6
HDO: 1
TPSA: 54.04
ALOGS: -2.30
ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Indigestion	indication	162031009

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	13.89	acidic
pKa2	7.96	Basic
pKa3	6.48	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Acetylcholinesterase	Enzyme	P22303	ACES_HUMAN		IC50	6.82		CHEMBL
Cholinesterase	Enzyme	P06276	CHLE_HUMAN		IC50	7.92		CHEMBL
Acetylcholinesterase	Enzyme		ACES_TORCA		IC50	5.76		CHEMBL

External reference:

ID	Source
D07914	KEGG_DRUG
5995-96-0	SECONDARY_CAS_RN
C0637914	UMLSCUI
CHEBI:4855	CHEBI
CHEMBL123248	ChEMBL_ID
65719	PUBCHEM_CID
C060406	MESH_SUPPLEMENTAL_RECORD_UI
5758	INN_ID
LW9S78L4M8	UNII
005663	NDDF
005664	NDDF
768343004	SNOMEDCT_US
CHEMBL539874	ChEMBL_ID

Pharmaceutical products:

None