citrulline Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3103 372-75-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • citrulline
  • L-Citrulline
  • sigma-Ureidonorvaline
  • Molecular weight: 175.19
  • Formula: C6H13N3O3
  • CLOGP: -3.36
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 4
  • TPSA: 118.44
  • ALOGS: -0.90
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Hyperammonemia off-label use 9360008
Arginase deficiency off-label use 23501004 DOID:9278
Congenital hyperammonemia, type I off-label use 62522004
Lysinuric protein intolerance off-label use 303852004 DOID:0060439
Ornithine Carbamyltransferase Deficiency off-label use
Arginosuccinate Lyase Deficiency off-label use

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.12 acidic
pKa2 11.32 acidic
pKa3 13.72 acidic
pKa4 9.52 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D002956 MESH_DESCRIPTOR_UI
4025081 VUID
N0000171745 NUI
C0008864 UMLSCUI
D07706 KEGG_DRUG
29VT07BGDA UNII
441997001 SNOMEDCT_US
30022007 SNOMEDCT_US
NOCODE MMSL
4025081 VANDF
004479 NDDF
2567 RXNORM
175680 MMSL
22711 MMSL
d06051 MMSL
9750 PUBCHEM_CID
CHEBI:18211 CHEBI
DB00155 DRUGBANK_ID
CHEMBL444814 ChEMBL_ID
CIR PDB_CHEM_ID
722 IUPHAR_LIGAND_ID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Lipovite HUMAN PRESCRIPTION DRUG LABEL 11 70104-128 INJECTION 1 mg INTRAMUSCULAR unapproved drug other 1 sections