cefuzonam 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, cefalosporanic acid derivatives 3077 82219-78-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cefuzonam
  • cefuzoname
  • cefuzonam sodium
article gives L-105 as synonym, however L 105 is a rifamycin derivative according to Chemline
  • Molecular weight: 513.58
  • Formula: C16H15N7O5S4
  • CLOGP: 0.25
  • LIPINSKI: 2
  • HAC: 12
  • HDO: 3
  • TPSA: 172.99
  • ALOGS: -3.42
  • ROTB: 8

Drug dosage:

None

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 0.20 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 4.10 mL/min/kg Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma) 0.12 % Lombardo F, Berellini G, Obach RS
t_half (Half-life) 1.14 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:36047 antibacterial drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.29 acidic
pKa2 13.31 acidic
pKa3 3.1 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01687 KEGG_DRUG
C0055017 UMLSCUI
CHEBI:55488 CHEBI
CHEMBL1689069 ChEMBL_ID
C049934 MESH_SUPPLEMENTAL_RECORD_UI
5888 INN_ID
82219-81-6 SECONDARY_CAS_RN
860MT00T7T UNII
6336505 PUBCHEM_CID

Pharmaceutical products:

None