All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

enbucrilate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
	3056	6606-65-1

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: n-butyl cyanoacrylate butyl cyanoacrylate butyl alpha-cyanoacrylate enbucrilate histacryl blue indermil n-Butyl 2-cyanoacrylate	A tissue adhesive that is applied as a monomer to moist tissue and polymerizes to form a bond. It is slowly biodegradable and used in all kinds of surgery, including dental. Molecular weight: 153.18 Formula: C8H11NO2 CLOGP: 1.82 LIPINSKI: 0 HAC: 3 HDO: 0 TPSA: 50.09 ALOGS: -2.08 ROTB: 5

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

Property	Description	Value	Unit	Confidence	Similarity
kinase-safety-class	ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FGFR1,FLT3,GRK2,GSK3B,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAPK10,MAPK7,MAPK9,MARK4,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIM2,PLK1,PLK2,PLK3,PLK4,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1	63
kinase-selectivity-class	AXL,BMX,GRK2,MAPK7,STK33,TEK	6
pfas-class	PFAS structural alert (1 = True, 0 = False)	0

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Product use in unapproved indication	111.01	103.26	29	49	336207	90292162

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Product use in unapproved indication	170.10	126.93	41	36	184415	42436843

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Product use in unapproved indication	255.76	128.24	69	122	447308	110141800

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
CHEBI has role	CHEBI:50177	dermatologic drug

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D07893	KEGG_DRUG
C0014035	UMLSCUI
CHEBI:134778	CHEBI
CHEMBL2104251	ChEMBL_ID
D004659	MESH_DESCRIPTOR_UI
DB12358	DRUGBANK_ID
3796	INN_ID
F8CEP82QNP	UNII
23087	PUBCHEM_CID
004461	NDDF
346412004	SNOMEDCT_US
409102000	SNOMEDCT_US

Pharmaceutical products:

None