butethamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3053 2090-89-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • butethamine
  • monocain
  • Molecular weight: 236.32
  • Formula: C13H20N2O2
  • CLOGP: 2.34
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 64.35
  • ALOGS: -3.04
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.74 Basic
pKa2 2.5 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Sodium channel alpha subunits; brain (Types I, II, III) Ion channel IC50 4.26 CHEMBL

External reference:

IDSource
C0301287 UMLSCUI
CHEBI:134959 CHEBI
CHEMBL124211 ChEMBL_ID
11117 PUBCHEM_CID
F8E12S0YYS UNII
004857 NDDF
71250002 SNOMEDCT_US

Pharmaceutical products:

None