bufetolol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
beta-adrenoreceptor antagonists 3046 53684-49-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bufetolol
  • bufetolol hydrochloride
  • bufetolol HCl
proposed beta adrenergic blockader similar to propranolol; minor desriptor (77-86); on line & INDEX MEDICUS search PROPANOLAMINES (77-86); RN given refers to parent compound
  • Molecular weight: 323.43
  • Formula: C18H29NO4
  • CLOGP: 2.08
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 59.95
  • ALOGS: -3.41
  • ROTB: 9

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D018663 Adrenergic Agents
MeSH PA D018674 Adrenergic Antagonists
MeSH PA D000319 Adrenergic beta-Antagonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.31 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01504 KEGG_DRUG
CHEBI:31316 CHEBI
CHEMBL347830 ChEMBL_ID
C100228 MESH_SUPPLEMENTAL_RECORD_UI
3412 INN_ID
35108-88-4 SECONDARY_CAS_RN
WS1467RT9Z UNII
C0107454 UMLSCUI
2465 PUBCHEM_CID

Pharmaceutical products:

None