benactyzine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
298 302-40-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • benactyzine
  • benactyzin
  • diethylaminoethyl benzilate
  • diazil
  • benactyzine hydrochloride
  • benactyzine HCl
A centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on behavior.
  • Molecular weight: 327.42
  • Formula: C20H25NO3
  • CLOGP: 3.76
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 49.77
  • ALOGS: -3.24
  • ROTB: 9

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000928 Antidepressive Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018678 Cholinergic Agents
MeSH PA D018680 Cholinergic Antagonists
MeSH PA D018727 Muscarinic Antagonists
MeSH PA D018377 Neurotransmitter Agents
MeSH PA D010276 Parasympatholytics
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D011619 Psychotropic Drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.56 acidic
pKa2 8.42 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019626 VUID
N0000147719 NUI
D07498 KEGG_DRUG
57-37-4 SECONDARY_CAS_RN
1361 RXNORM
C0004962 UMLSCUI
CHEBI:94775 CHEBI
CHEMBL70352 ChEMBL_ID
DB09023 DRUGBANK_ID
D001535 MESH_DESCRIPTOR_UI
9330 PUBCHEM_CID
496 INN_ID
595EG71R3F UNII
001505 NDDF
004604 NDDF
4018455 VANDF
4019626 VANDF
412215005 SNOMEDCT_US
52275001 SNOMEDCT_US

Pharmaceutical products:

None