peplomycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 2965 68247-85-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • peplomycin
  • Bleomycin PEP
  • pepleomycin
  • peplomycin sulfate
  • NK631
  • NK-631
An antineoplastic agent derived from BLEOMYCIN.
  • Molecular weight: 1473.60
  • Formula: C61H88N18O21S2
  • CLOGP: -6.26
  • LIPINSKI: 3
  • HAC: 39
  • HDO: 21
  • TPSA: 639.10
  • ALOGS: -4.61
  • ROTB: 38

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000903 Antibiotics, Antineoplastic
MeSH PA D000970 Antineoplastic Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.98 acidic
pKa2 12.42 acidic
pKa3 12.77 acidic
pKa4 12.99 acidic
pKa5 13.22 acidic
pKa6 13.22 acidic
pKa7 13.42 acidic
pKa8 13.72 acidic
pKa9 13.89 acidic
pKa10 8.84 Basic
pKa11 7.07 Basic
pKa12 5.21 Basic
pKa13 4.48 Basic
pKa14 3.07 Basic
pKa15 2.23 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02063 KEGG_DRUG
70384-29-1 SECONDARY_CAS_RN
C0135981 UMLSCUI
CHEBI:135909 CHEBI
CHEMBL3990196 ChEMBL_ID
CHEMBL3989633 ChEMBL_ID
D017663 MESH_DESCRIPTOR_UI
4833 INN_ID
56H9L80NIZ UNII
6852373 PUBCHEM_CID

Pharmaceutical products:

None