gonadorelin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
pituitary hormone-release stimulating peptides 2958 33515-09-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • gonadorelin
  • Luteinizing hormone-releasing factor (swine)
  • hypocrine
  • fertagyl
  • gonadorelin hydrochloride
  • gonadorelin acetate
  • gonadorelin HCl
  • gonadorelin diacetate tetrahydrate
A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
  • Molecular weight: 1182.31
  • Formula: C55H75N17O13
  • CLOGP: -6.31
  • LIPINSKI: 3
  • HAC: 30
  • HDO: 17
  • TPSA: 472.13
  • ALOGS: -4.33
  • ROTB: 31
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

🐶 Veterinary products

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

gonadorelin