arotinolol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
beta-adrenoreceptor antagonists 243 68377-92-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • arotinolol
  • arotinolol hydrochloride
  • arotinolol HCl
  • Molecular weight: 371.53
  • Formula: C15H21N3O2S3
  • CLOGP: 2.08
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 88.24
  • ALOGS: -4.22
  • ROTB: 8

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D018663 Adrenergic Agents
MeSH PA D000317 Adrenergic alpha-Antagonists
MeSH PA D018674 Adrenergic Antagonists
MeSH PA D000319 Adrenergic beta-Antagonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.81 acidic
pKa2 9.91 Basic
pKa3 1.09 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07465 KEGG_DRUG
C0104221 UMLSCUI
CHEBI:31239 CHEBI
CHEMBL93298 ChEMBL_ID
DB09204 DRUGBANK_ID
C024523 MESH_SUPPLEMENTAL_RECORD_UI
2239 PUBCHEM_CID
5215 INN_ID
68377-91-3 SECONDARY_CAS_RN
394E3P3B99 UNII
008153 NDDF
008154 NDDF

Pharmaceutical products:

None