aranidipine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
calcium channel blockers, nifedipine derivatives	234	86780-90-7

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

aranidipine
sapresta

Molecular weight: 388.38
Formula: C19H20N2O7
CLOGP: 2.56
LIPINSKI: 0
HAC: 9
HDO: 1
TPSA: 124.84
ALOGS: -4.54
ROTB: 8

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hypertensive disorder	indication	38341003	DOID:10763

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	2.5	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Voltage-gated L-type calcium channel	Ion channel	Q01668 Q13936	CAC1D_HUMAN CAC1C_HUMAN	BLOCKER				DRUG LABEL	KEGG DRUG

External reference:

ID	Source
D01562	KEGG_DRUG
C0165312	UMLSCUI
CHEBI:31232	CHEBI
CHEMBL2104030	ChEMBL_ID
DB09229	DRUGBANK_ID
C059427	MESH_SUPPLEMENTAL_RECORD_UI
2225	PUBCHEM_CID
11744	IUPHAR_LIGAND_ID
7071	INN_ID
4Y7UR6X2PO	UNII

Pharmaceutical products:

None