pyricarbate Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2329 1882-26-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pyricarbate
  • anginin
  • anginine
  • angioxine
  • pyridinol carbamate
  • prodectin
A drug that has been given by mouth in the treatment of atherosclerosis and other vascular disorders, hyperlipidemias, and thrombo-embolic disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1408)
  • Molecular weight: 253.26
  • Formula: C11H15N3O4
  • CLOGP: -0.42
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 2
  • TPSA: 89.55
  • ALOGS: -2.74
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000963 Antimetabolites
MeSH PA D000960 Hypolipidemic Agents
MeSH PA D057847 Lipid Regulating Agents
MeSH PA D002317 Cardiovascular Agents
MeSH PA D053834 Explosive Agents
MeSH PA D014665 Vasodilator Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.25 acidic
pKa2 13.85 acidic
pKa3 4.64 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000166706 NUI
D01396 KEGG_DRUG
C0795717 UMLSCUI
CHEBI:32075 CHEBI
CHEMBL1620144 ChEMBL_ID
D011727 MESH_DESCRIPTOR_UI
D005996 MESH_DESCRIPTOR_UI
4990 PUBCHEM_CID
5011 INN_ID
81R511UV73 UNII
8997 RXNORM
007074 NDDF

Pharmaceutical products:

None