plafibride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2221 63394-05-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • plafibride
  • perifunal
  • idonor
morpholino-methylurea analog of clofibric acid
  • Molecular weight: 355.82
  • Formula: C16H22ClN3O4
  • CLOGP: 2.77
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 2
  • TPSA: 79.90
  • ALOGS: -3.10
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000963 Antimetabolites
MeSH PA D006401 Hematologic Agents
MeSH PA D000960 Hypolipidemic Agents
MeSH PA D057847 Lipid Regulating Agents
MeSH PA D010975 Platelet Aggregation Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.9 acidic
pKa2 5.67 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0071199 UMLSCUI
CHEBI:135503 CHEBI
CHEMBL2107129 ChEMBL_ID
C016894 MESH_SUPPLEMENTAL_RECORD_UI
68822 PUBCHEM_CID
4418 INN_ID
5J7C4JZ564 UNII

Pharmaceutical products:

None