pipobroman 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2192 54-91-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pipobroman
  • amedel
  • vercyte
An antineoplastic agent that acts by alkylation.
  • Molecular weight: 356.06
  • Formula: C10H16Br2N2O2
  • CLOGP: 0.23
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 40.62
  • ALOGS: -2.20
  • ROTB: 4

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
S (Water solubility) 2.24 mg/mL Bocci G, Oprea TI, Benet LZ
BDDCS (Biopharmaceutical Drug Disposition Classification System) 1 Bocci G, Oprea TI, Benet LZ

Approvals:

DateAgencyCompanyOrphan
July 1, 1966 FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC L01AX02 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
ALKYLATING AGENTS
Other alkylating agents
MeSH PA D000477 Alkylating Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018906 Antineoplastic Agents, Alkylating
MeSH PA D009676 Noxae
CHEBI has role CHEBI:35610 antineoplastic agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018739 VUID
N0000147043 NUI
D00467 KEGG_DRUG
4018739 VANDF
C0031965 UMLSCUI
CHEBI:8242 CHEBI
CHEMBL1585 ChEMBL_ID
DB00236 DRUGBANK_ID
D010885 MESH_DESCRIPTOR_UI
4842 PUBCHEM_CID
7271 IUPHAR_LIGAND_ID
2049 INN_ID
6Q99RDT97R UNII
8347 RXNORM
002099 NDDF
24823004 SNOMEDCT_US

Pharmaceutical products:

None