All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

aminosalicylic acid hydrazide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
	2051	6946-29-8

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: aminosalicylic acid hydrazide 4-Aminosalicylic acid hydrazide apacizin apacizina pasdrazide p-aminosalicylic acid hydrazide	Molecular weight: 167.17 Formula: C7H9N3O2 CLOGP: -0.24 LIPINSKI: 0 HAC: 5 HDO: 4 TPSA: 101.37 ALOGS: -1.38 ROTB: 1

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

Property	Description	Value	Unit	Confidence	Similarity
kinase-safety-class	ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GRK3,GSK3B,IGF1R,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,KIT,MAP2K6,MAP3K1,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAP4K3,MAPK1,MAPK10,MAPK12,MAPK14,MAPK7,MAPK8,MAPK9,MAPKAPK2,MAPKAPK5,MARK4,MELK,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ULK2,ZAP70	73
kinase-selectivity-class	ACVR2A,ACVR2B,AXL,CAMK2D,CDK4,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,GRK3,MAP2K3,MAP2K6,MAP3K14,MAP3K21,MAPK12,MAPK7,MAPK8,MARK4,SGK1,SIK2,SIK3,STK33,TEK,TTK,ULK1	28
pfas-class	PFAS structural alert (1 = True, 0 = False)	0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	8.53	acidic
pKa2	12.05	acidic
pKa3	3.0	Basic
pKa4	2.18	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
72490	PUBCHEM_CID
CHEBI:134800	CHEBI
ODX97PJ52T	UNII

Pharmaceutical products:

None