DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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Structure 🔎
Similarity 🔎
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
Scroll
Substructure SMILES Example:
n1cnccc1
pamabrom 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
2047
10381-75-6
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
8-bromotheophylline
bromotheophylline
pamabrom
predema
Molecular weight: 259.06
Formula: C7H7BrN4O2
CLOGP: 0.93
LIPINSKI: 0
HAC: 6
HDO: 1
TPSA: 69.30
ALOGS: -1.82
ROTB: 0
Drug dosage:
None
ADMET properties:
None
Approvals:
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Date
Agency
Company
Orphan
None
FDA
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1
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Ocular hypertension
contraindication
4210003
DOID:9282
Alcoholism
contraindication
7200002
Peptic ulcer
contraindication
13200003
DOID:750
Hyperthyroidism
contraindication
34486009
DOID:7998
Hypertensive disorder
contraindication
38341003
DOID:10763
Hepatic failure
contraindication
59927004
Blood coagulation disorder
contraindication
64779008
DOID:1247
Poisoning by acetaminophen
contraindication
70273001
Chronic idiopathic constipation
contraindication
82934008
Disease of liver
contraindication
235856003
DOID:409
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
6.87
acidic
pKa2
2.43
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Adenosine receptor A1
GPCR
AA1R_RAT
Ki
4.99
CHEMBL
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External reference:
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entries
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ID
Source
002318
NDDF
116552006
SNOMEDCT_US
11806
PUBCHEM_CID
1546386
RXNORM
398981003
SNOMEDCT_US
4019460
VUID
4019460
VANDF
5225
MMSL
606-04-2
SECONDARY_CAS_RN
C0135166
UMLSCUI
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
Fem Relief
HUMAN OTC DRUG LABEL
2
0498-7000
TABLET
25 mg
ORAL
OTC monograph not final
15 sections
Fem Relief
HUMAN OTC DRUG LABEL
2
0498-7001
TABLET
25 mg
ORAL
OTC monograph not final
15 sections
Green Guard Cramp Relief
HUMAN OTC DRUG LABEL
3
47682-049
TABLET, FILM COATED
25 mg
ORAL
OTC monograph not final
17 sections
Green Guard PMS Relief
HUMAN OTC DRUG LABEL
2
47682-016
TABLET, FILM COATED
25 mg
ORAL
OTC monograph not final
15 sections
Green Guard PMS Relief
HUMAN OTC DRUG LABEL
2
47682-016
TABLET, FILM COATED
25 mg
ORAL
OTC monograph not final
15 sections
Green Guard PMS Relief
HUMAN OTC DRUG LABEL
2
47682-016
TABLET, FILM COATED
25 mg
ORAL
OTC monograph not final
15 sections
Leader Premenstrual
HUMAN OTC DRUG LABEL
3
37205-339
CAPSULE
25 mg
ORAL
OTC monograph not final
16 sections
Medi First Cramp
HUMAN OTC DRUG LABEL
2
47682-810
TABLET, FILM COATED
25 mg
ORAL
OTC monograph not final
15 sections
Medi First Cramp
HUMAN OTC DRUG LABEL
2
47682-810
TABLET, FILM COATED
25 mg
ORAL
OTC monograph not final
15 sections
Medi First Cramp
HUMAN OTC DRUG LABEL
2
47682-810
TABLET, FILM COATED
25 mg
ORAL
OTC monograph not final
15 sections
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pamabrom