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niridazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 1941 | 61-57-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An antischistosomal agent that has become obsolete.
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,ALK,AURKA,AURKB,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK1,CDK5,CDK9,CHEK1,CSF1R,DDR1,DYRK1B,EGFR,EIF2AK3,ERBB2,FLT3,GRK2,GRK3,GSK3B,IRAK1,ITK,JAK1,JAK2,KIT,MAP2K6,MAP3K1,MAP3K11,MAP3K21,MAP3K7,MAP4K1,MAP4K3,MAPK10,MAPK7,MAPK9,MAPKAPK2,MARK4,MELK,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1,ULK2 | 65 | |||
| kinase-selectivity-class | AXL,BRAF,CAMK2D,CDK9,DDR1,DYRK1B,GRK2,GSK3A,GSK3B,IRAK1,MAP2K6,MAP3K21,MAPK7,MET,PDK1,SIK2,STK33,TEK,TTK,ULK1 | 20 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | P02BX02 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTHELMINTICS ANTITREMATODALS Other antitrematodal agents |
| MeSH PA | D000563 | Amebicides |
| MeSH PA | D000871 | Anthelmintics |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000977 | Antiparasitic Agents |
| MeSH PA | D000980 | Antiplatyhelmintic Agents |
| MeSH PA | D000981 | Antiprotozoal Agents |
| MeSH PA | D012556 | Schistosomicides |
| CHEBI has role | CHEBI:35443 | anthelminthic drug |
Related Drugs by ATC class:
P02BX Other antitrematodal agents 3 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.72 | acidic |
| pKa2 | 0.75 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D05170 | KEGG_DRUG |
| C0028113 | UMLSCUI |
| CHEBI:82349 | CHEBI |
| CHEMBL152632 | ChEMBL_ID |
| DB13661 | DRUGBANK_ID |
| D009560 | MESH_DESCRIPTOR_UI |
| 6093 | PUBCHEM_CID |
| 2234 | INN_ID |
| N116U8Y5QQ | UNII |
| 006108 | NDDF |
| 55944008 | SNOMEDCT_US |
Pharmaceutical products:
None