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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
amperozide 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
193
75558-90-6
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
amperozide
Molecular weight: 401.50
Formula: C23H29F2N3O
CLOGP: 5.37
LIPINSKI: 1
HAC: 4
HDO: 1
TPSA: 35.58
ALOGS: -4.49
ROTB: 7
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
CHEBI has role
CHEBI:35474
anti-anxiety agents
CHEBI has role
CHEBI:48279
serotonin antagonists
CHEBI has role
CHEBI:51039
dopamine reuptake inhibitor
CHEBI has role
CHEBI:65191
atypical antipsychotic agent
CHEBI has role
CHEBI:176497
geroprotectors
MeSH PA
D014150
Antipsychotic Agents
MeSH PA
D002491
Central Nervous System Agents
MeSH PA
D002492
Central Nervous System Depressants
MeSH PA
D018377
Neurotransmitter Agents
MeSH PA
D011619
Psychotropic Drugs
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
12.94
acidic
pKa2
8.09
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Fatty-acid amide hydrolase 1
Enzyme
O00519
FAAH1_HUMAN
IC50
6.34
CHEMBL
5-hydroxytryptamine receptor 6
GPCR
P50406
5HT6R_HUMAN
Ki
5.80
PDSP
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External reference:
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ID
Source
0M2W3TAG39
UNII
5033
INN_ID
73333
PUBCHEM_CID
C0051747
UMLSCUI
C049058
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:180480
CHEBI
CHEMBL1079935
ChEMBL_ID
DB08927
DRUGBANK_ID
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Pharmaceutical products:
None
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Structure 🔎
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amperozide