amosulalol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
aromatic ring -CH(-OH)-CH2-NH-R 190 85320-68-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • amosulalol hydrochloride
  • amosulalol
  • amosulalol HCl
  • Molecular weight: 380.46
  • Formula: C18H24N2O5S
  • CLOGP: 1.06
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 110.88
  • ALOGS: -3.60
  • ROTB: 9

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 99 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D018663 Adrenergic Agents
MeSH PA D000317 Adrenergic alpha-Antagonists
MeSH PA D018674 Adrenergic Antagonists
MeSH PA D000319 Adrenergic beta-Antagonists
MeSH PA D000959 Antihypertensive Agents
MeSH PA D002317 Cardiovascular Agents
MeSH PA D018377 Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.27 acidic
pKa2 7.54 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01469 KEGG_DRUG
70958-86-0 SECONDARY_CAS_RN
C0103116 UMLSCUI
CHEBI:31208 CHEBI
CHEMBL152231 ChEMBL_ID
C032473 MESH_SUPPLEMENTAL_RECORD_UI
2169 PUBCHEM_CID
5409 INN_ID
C69JI1BAU8 UNII
010910 NDDF
010911 NDDF

Pharmaceutical products:

None