nandrolone phenpropionate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
steroids, androgens 1882 62-90-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • nandrolone phenpropionate
  • nandrolon phenylpropionate
  • nandrolone phenylpropionate
  • norandrolone phenylpropionate
  • norandrostenolone phenylpropionate
  • nortestosterone phenylpropionate
  • Molecular weight: 406.57
  • Formula: C27H34O3
  • CLOGP: 5.93
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 0
  • TPSA: 43.37
  • ALOGS: -5.95
  • ROTB: 5
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
MRTD (Maximum Recommended Therapeutic Daily Dose) 8.19 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
S (Water solubility) 3.09 mg/mL Bocci G, Oprea TI, Benet LZ
BA (Bioavailability) 2 %

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,CAMK2D,CDK5,EIF2AK3,ERBB2,GRK2,ITK,MAPK10,MAPKAPK2,PDK1,PDK2,PDK4,PIK3CG,PRKDC 16
kinase-selectivity-class AXL,EIF2AK3,GRK2 3
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
Oct. 30, 1959 FDA ORGANON USA INC

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D006728 Hormones
MeSH PA D045930 Anabolic Agents
MeSH PA D000728 Androgens
FDA EPC N0000175824 Androgen
CHEBI has role CHEBI:75835 anti-anaemic agent
CHEBI has role CHEBI:77746 human metabolite
CHEBI has role CHEBI:36413 anabolic agent
CHEBI has role CHEBI:50113 androgen

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Androgen receptor Nuclear hormone receptor AGONIST EC50 9.50 WOMBAT-PK CHEMBL
Estrogen receptor Nuclear hormone receptor EC50 6.70 WOMBAT-PK

External reference:

IDSource
4018518 VUID
N0000179201 NUI
D00956 KEGG_DRUG
4018518 VANDF
4019854 VANDF
C0068397 UMLSCUI
CHEBI:7468 CHEBI
CHEMBL1200412 ChEMBL_ID
DB00984 DRUGBANK_ID
C008580 MESH_SUPPLEMENTAL_RECORD_UI
229455 PUBCHEM_CID
KF7Z9K2T3W UNII
31495 RXNORM
2095 MMSL
5153 MMSL
5464 MMSL
d00568 MMSL
001259 NDDF
001261 NDDF
109037003 SNOMEDCT_US
126171003 SNOMEDCT_US
86162003 SNOMEDCT_US
C0027368 UMLSCUI
DB13169 DRUGBANK_ID
9904 PUBCHEM_CID
295 INN_ID
D009277 MESH_DESCRIPTOR_UI
CHEBI:7466 CHEBI
KF7Z9K2T3W INXIGHT DRUGS

Pharmaceutical products:

None