micinicate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
antihypercholesterolaemic and/or vasodilating nicotinic acid esters 1799 39537-99-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cyclandelate nicotinate
  • micinicate
  • nicotinoyl cyclandelate
  • Molecular weight: 381.47
  • Formula: C23H27NO4
  • CLOGP: 5.59
  • LIPINSKI: 1
  • HAC: 5
  • HDO: 0
  • TPSA: 65.49
  • ALOGS: -4.81
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PRKDC,STK33,TEK,TTK 24
kinase-selectivity-class AXL,GRK2 2
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.23 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C2983979 UMLSCUI
CHEBI:135596 CHEBI
CHEMBL2105268 ChEMBL_ID
20055289 PUBCHEM_CID
4872 INN_ID
M87S131A7F UNII

Pharmaceutical products:

None