DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
Scroll
Substructure SMILES Example:
n1cnccc1
methylthiouracil 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
uracil derivatives used as thyroid antagonists
1773
56-04-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
methylthiouracil
thiomecil
6-Methyl-2-thiouracil
thiothymin
A thiourea antithyroid agent that inhibits the synthesis of thyroid hormone. It is used in the treatment of hyperthyroidism.
Molecular weight: 142.18
Formula: C5H6N2OS
CLOGP: -0.09
LIPINSKI: 0
HAC: 3
HDO: 2
TPSA: 41.13
ALOGS: -1.88
ROTB: 0
Drug dosage:
Dose
Unit
Route
0.10
g
O
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
Show
10
25
50
100
entries
Search:
Source
Code
Description
ATC
H03BA01
SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
THYROID THERAPY
ANTITHYROID PREPARATIONS
Thiouracils
MeSH PA
D013956
Antithyroid Agents
MeSH PA
D006727
Hormone Antagonists
Showing 1 to 3 of 3 entries
Previous
1
Next
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
Show
10
25
50
100
entries
Search:
Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
8.9
acidic
Showing 1 to 1 of 1 entries
Previous
1
Next
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
Show
10
25
50
100
entries
Search:
ID
Source
002138
NDDF
387356006
SNOMEDCT_US
4150
INN_ID
64878006
SNOMEDCT_US
667493
PUBCHEM_CID
C000599236
MESH_SUPPLEMENTAL_RECORD_UI
C0025830
UMLSCUI
CHEBI:82346
CHEBI
CHEMBL1330588
ChEMBL_ID
D008779
MESH_DESCRIPTOR_UI
Showing 1 to 10 of 13 entries
Previous
1
2
Next
Pharmaceutical products:
None
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
methylthiouracil