methylprednisolone succinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 1771 2921-57-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methylprednisolone succinate
  • methylprednisolone hemisuccinate
  • methylprednisolone sodium succinate
A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.
  • Molecular weight: 474.55
  • Formula: C26H34O8
  • CLOGP: 2.05
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 138.20
  • ALOGS: -4.25
  • ROTB: 7
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
S (Water solubility) 0.12 mg/mL Bocci G, Oprea TI, Benet LZ
BA (Bioavailability) 82 %

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
azlogd74 LogD at pH 7.4 0.125 Moderate 0.71
caco2-efflux Caco-2 efflux ratio (BA/AB) 6.223 Moderate 0.71
caco2-intrinsic-papp Caco-2 intrinsic apparent permeability 5.808 10^-6 cm/s Moderate 0.71
dh-clint Dog hepatocyte intrinsic clearance 4.375 uL/min/10^6 cells Moderate 0.71
dppb Dog plasma protein binding (% unbound) 15.010 % Moderate 0.71
fcs-ppb Fetal calf serum protein binding (% unbound) 26.060 % Moderate 0.71
herg hERG pIC50 4.419 pIC50 Moderate 0.71
hh-clint Human hepatocyte intrinsic clearance 4.842 uL/min/10^6 cells Moderate 0.71
hlm-clint Human liver microsomal intrinsic clearance 6.653 uL/min/mg protein Moderate 0.71
hppb Human plasma protein binding (% unbound) 11.910 % Moderate 0.71
kinase-safety-class ACVR2B,AXL,CDK5,EIF2AK3,ERBB2,GRK2,ITK,MAPK7,PDK1,PDK2,PDK4,PRKDC,TEK 13
kinase-selectivity-class GRK2,MAP2K6 2
mdck-mdr1-efflux MDCK-MDR1 efflux ratio 2.972 Moderate 0.71
mh-clint Mouse hepatocyte intrinsic clearance 51.642 Moderate 0.71
mppb Mouse plasma protein binding (% unbound) 22.110 Moderate 0.71
nih-mdck-mdr1-efflux NIH MDCK-MDR1 efflux ratio 3.475 Moderate 0.71
pfas-class PFAS structural alert (1 = True, 0 = False) 0
pppb Pig plasma protein binding (% unbound) 17.550 % Moderate 0.71
rh-clint Rat hepatocyte intrinsic clearance 52.360 uL/min/10^6 cells Moderate 0.71
rh-fuinc Rat hepatocyte fraction unbound in incubation 82.620 % Moderate 0.71
rppb Rat plasma protein binding (% unbound) 9.680 % Moderate 0.71
solubility-dd Solubility at pH 7.4 in DMSO 839.460 uM Moderate 0.71

Approvals:

DateAgencyCompanyOrphan
May 18, 1959 FDA PHARMACIA AND UPJOHN

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 1204.41 9.58 9292 430727 1092960 89095468
Cytomegalovirus infection 994.59 9.58 909 439110 25693 90162735
Completed suicide 639.93 9.58 13 440006 145045 90043383
Blood pressure fluctuation 637.41 9.58 1010 439009 51403 90137025
Infusion related reaction 591.58 9.58 3752 436267 413028 89775400
Drug ineffective for unapproved indication 580.10 9.58 1108 438911 65536 90122892
Throat irritation 573.82 9.58 925 439094 47770 90140658
Blood pressure systolic abnormal 488.64 9.58 536 439483 18942 90169486
Blood pressure diastolic abnormal 484.78 9.58 539 439480 19342 90169086
Product dose omission issue 458.28 9.58 444 439575 291243 89897185
Toxicity to various agents 417.44 9.58 469 439550 287377 89901051
Blood pressure systolic increased 384.27 9.58 865 439154 57480 90130948
Death 379.90 9.58 1055 438964 455496 89732932
Transplant rejection 378.64 9.58 384 439635 12374 90176054
Injection site pain 367.69 9.58 192 439827 173507 90014921
Oxygen saturation decreased 353.04 9.58 1237 438782 106246 90082182
Bronchopulmonary aspergillosis 327.25 9.58 337 439682 11061 90177367
Cytomegalovirus viraemia 326.89 9.58 281 439738 7305 90181123
Intentional overdose 325.89 9.58 37 439982 93797 90094631
Blood pressure increased 318.93 9.58 1838 438181 195379 89993049
Aspergillus infection 316.18 9.58 323 439696 10500 90177928
Haemophagocytic lymphohistiocytosis 298.60 9.58 372 439647 15087 90173341
Lymphocyte count decreased 291.80 9.58 572 439447 34478 90153950
Thrombotic microangiopathy 288.47 9.58 369 439650 15374 90173054
Cytomegalovirus infection reactivation 284.62 9.58 263 439756 7537 90180891
Ear pruritus 283.04 9.58 247 439772 6556 90181872
Posterior reversible encephalopathy syndrome 281.96 9.58 438 439581 21901 90166527
Blood pressure diastolic decreased 271.28 9.58 476 439543 26350 90162078
Rheumatoid arthritis 264.23 9.58 2807 437212 359807 89828621
Urine abnormality 263.36 9.58 251 439768 7486 90180942
Drug abuse 254.49 9.58 46 439973 82301 90106127
Multiple organ dysfunction syndrome 254.01 9.58 820 439199 67516 90120912
Heart rate decreased 252.89 9.58 699 439320 52806 90135622
BK virus infection 227.89 9.58 183 439836 4315 90184113
Product use in unapproved indication 223.86 9.58 2557 437462 333679 89854749
Epstein-Barr virus infection 222.72 9.58 263 439756 10081 90178347
Post transplant lymphoproliferative disorder 222.53 9.58 218 439801 6731 90181697
Diarrhoea 217.49 9.58 3232 436787 935958 89252470
Polyomavirus-associated nephropathy 217.47 9.58 141 439878 2349 90186079
Wrong technique in product usage process 214.75 9.58 43 439976 71528 90116900
Klebsiella infection 213.80 9.58 257 439762 10040 90178388
Injection site erythema 212.70 9.58 106 439913 98396 90090032
Dehydration 210.53 9.58 389 439630 194058 89994370
Pneumocystis jirovecii pneumonia 210.13 9.58 377 439642 21239 90167189
Urine leukocyte esterase positive 209.03 9.58 153 439866 3129 90185299
Hypercholesterolaemia 201.66 9.58 997 439022 99895 90088533
Alopecia 201.11 9.58 1492 438527 493579 89694849
White blood cells urine positive 200.94 9.58 200 439819 6298 90182130
Urinary sediment present 199.49 9.58 127 439892 2047 90186381
Fall 197.16 9.58 1449 438570 480361 89708067
Red blood cells urine positive 182.37 9.58 140 439879 3085 90185343
Fatigue 180.20 9.58 4251 435768 1149772 89038656
Suicide attempt 178.72 9.58 71 439948 75328 90113100
Kidney transplant rejection 177.67 9.58 164 439855 4693 90183735
Heart rate increased 175.74 9.58 1042 438977 111860 90076568
Nocardiosis 175.54 9.58 125 439894 2445 90185983
Device expulsion 175.15 9.58 5 440014 40881 90147547
Enterococcal infection 168.78 9.58 225 439794 9766 90178662
Cardiac failure congestive 160.98 9.58 145 439874 98549 90089879
Drug effective for unapproved indication 160.11 9.58 195 439824 7723 90180705
C-reactive protein increased 158.58 9.58 1459 438560 179930 90008498
Hospitalisation 157.43 9.58 236 439783 127864 90060564
Crystal urine present 156.87 9.58 95 439924 1395 90187033
Cytomegalovirus test positive 156.73 9.58 134 439885 3457 90184971
Respiratory failure 152.79 9.58 1042 438977 117376 90071052
Pharyngeal paraesthesia 152.08 9.58 125 439894 3049 90185379
Temperature regulation disorder 151.71 9.58 262 439757 14317 90174111
Malignant neoplasm progression 149.50 9.58 179 439840 106691 90081737
Cushingoid 148.54 9.58 216 439803 10179 90178249
Complications of transplanted kidney 147.74 9.58 118 439901 2760 90185668
Mucormycosis 147.55 9.58 133 439886 3688 90184740
Acute graft versus host disease in skin 142.68 9.58 144 439875 4612 90183816
Erythema 142.06 9.58 1720 438299 227526 89960902
Varicella zoster virus infection 141.99 9.58 131 439888 3746 90184682
Steroid diabetes 140.14 9.58 108 439911 2394 90186034
Coeliac disease 140.04 9.58 506 439513 44104 90144324
Pneumomediastinum 139.22 9.58 99 439920 1932 90186496
Injection site swelling 137.54 9.58 59 439960 59780 90128648
Drug interaction 136.51 9.58 785 439234 275668 89912760
Onychomadesis 135.39 9.58 511 439508 45487 90142941
Delayed graft function 135.14 9.58 85 439934 1340 90187088
Accidental exposure to product 134.56 9.58 22 439997 42344 90146084
Progressive multifocal leukoencephalopathy 132.13 9.58 257 439762 15398 90173030
Food allergy 131.59 9.58 344 439675 25134 90163294
Serotonin syndrome 131.38 9.58 15 440004 37872 90150556
Pseudomonas infection 130.33 9.58 248 439771 14617 90173811
Graft versus host disease in gastrointestinal tract 130.07 9.58 132 439887 4256 90184172
Immunodeficiency 129.50 9.58 483 439536 42751 90145677
Hypertension 129.32 9.58 3019 437000 454513 89733915
Lymphopenia 127.58 9.58 318 439701 22563 90165865
Pneumatosis intestinalis 127.56 9.58 117 439902 3320 90185108
Vomiting 127.35 9.58 2887 437132 785406 89403022
Cytomegalovirus colitis 127.10 9.58 116 439903 3270 90185158
Systemic candida 127.04 9.58 138 439881 4821 90183607
Sedation 126.87 9.58 38 439981 48133 90140295
Nausea 126.29 9.58 4273 435746 1106043 89082385
Adenovirus infection 124.35 9.58 132 439887 4490 90183938
Therapy interrupted 122.39 9.58 45 439974 50063 90138365
Orthostatic hypotension 121.63 9.58 27 439992 41800 90146628
Graft versus host disease 120.43 9.58 172 439847 7972 90180456
Hyponatraemia 119.63 9.58 297 439722 133241 90055187
Onychomycosis 119.07 9.58 426 439593 36950 90151478
Myocardial infarction 118.24 9.58 208 439811 105764 90082664
Injection site pruritus 117.62 9.58 57 439962 53777 90134651
Lymphocyte percentage decreased 117.13 9.58 107 439912 3020 90185408
Neutrophil percentage increased 116.89 9.58 105 439914 2898 90185530
Injection site bruising 116.40 9.58 54 439965 52253 90136175
Hypoglycaemia 114.65 9.58 102 439917 69746 90118682
Reversible cerebral vasoconstriction syndrome 112.98 9.58 119 439900 4011 90184417
Human herpesvirus 6 infection 112.39 9.58 109 439910 3323 90185105
COVID-19 111.71 9.58 1283 438736 167560 90020868
Bursitis 110.04 9.58 1049 438970 130605 90057823
Blepharospasm 109.40 9.58 546 439473 54899 90133529
Acinetobacter infection 108.82 9.58 85 439934 1923 90186505
Herpes simplex 105.98 9.58 183 439836 9998 90178430
Blood urine present 105.82 9.58 249 439770 17029 90171399
Flushing 105.54 9.58 764 439255 87727 90100701
Escherichia infection 105.00 9.58 236 439783 15659 90172769
Oedema peripheral 104.67 9.58 777 439242 257138 89931290
Graft versus host disease in skin 103.59 9.58 110 439909 3743 90184685
Syncope 102.49 9.58 317 439702 132346 90056082
Back injury 101.28 9.58 472 439547 46150 90142278
Septic shock 100.60 9.58 727 439292 83433 90104995
Pneumonia cytomegaloviral 100.37 9.58 98 439921 3013 90185415
Wound infection 98.13 9.58 866 439153 105536 90082892
Multiple sclerosis relapse 96.86 9.58 506 439513 51799 90136629
Urine analysis abnormal 96.63 9.58 123 439896 5098 90183330
Disease recurrence 96.07 9.58 400 439619 37253 90151175
Intentional self-injury 95.97 9.58 14 440005 29320 90159108
Blood pressure diastolic increased 95.96 9.58 201 439818 12705 90175723
Therapy cessation 95.18 9.58 29 439990 36332 90152096
Immunosuppressant drug level increased 94.21 9.58 115 439904 4565 90183863
Abdominal discomfort 94.00 9.58 1691 438328 475637 89712791
Acute kidney injury 93.54 9.58 1049 438970 319338 89869090
Hypogammaglobulinaemia 93.48 9.58 178 439841 10496 90177932
Chest discomfort 93.13 9.58 1055 438964 137310 90051118
Depressed level of consciousness 92.44 9.58 131 439888 72653 90115775
Constipation 92.08 9.58 893 439126 279502 89908926
Myopathy 90.74 9.58 202 439817 13316 90175112
Acute respiratory distress syndrome 90.56 9.58 326 439693 28360 90160068
Nail disorder 88.59 9.58 540 439479 58527 90129901
Osteonecrosis of jaw 87.58 9.58 40 439979 39063 90149365
Arterial occlusive disease 86.96 9.58 189 439830 12257 90176171
Osteonecrosis 86.95 9.58 303 439716 25938 90162490
Pulmonary nocardiosis 86.91 9.58 52 439967 746 90187682
Blood calcium decreased 86.73 9.58 20 439999 30162 90158266
Pulmonary mucormycosis 86.62 9.58 47 439972 553 90187875
Suicidal ideation 86.03 9.58 141 439878 73714 90114714
Device issue 86.02 9.58 19 440000 29518 90158910
Neuropathy peripheral 85.42 9.58 358 439661 136612 90051816
Loss of consciousness 85.34 9.58 370 439649 139868 90048560
Swelling 85.22 9.58 1476 438543 417582 89770846
Sopor 84.85 9.58 10 440009 24634 90163794
Bacterial test 84.12 9.58 58 439961 1075 90187353
Bacterial test positive 83.40 9.58 118 439901 5421 90183007
Acute graft versus host disease in intestine 83.39 9.58 74 439945 2009 90186419
Drug ineffective 83.05 9.58 7796 432223 1376502 88811926
Enterobacter infection 80.79 9.58 80 439939 2503 90185925
Oral pruritus 80.67 9.58 85 439934 2866 90185562
Contraindicated product administered 80.29 9.58 1083 438936 319056 89869372
Dyspnoea 79.29 9.58 3484 436535 877471 89310957
Drug-induced liver injury 79.13 9.58 727 439292 89591 90098837
Rebound effect 79.13 9.58 154 439865 9230 90179198
Systemic mycosis 79.11 9.58 63 439956 1467 90186961
Pulmonary alveolar haemorrhage 79.05 9.58 120 439899 5878 90182550
Muscular weakness 78.81 9.58 1426 438593 205240 89983188
Epstein-Barr virus associated lymphoproliferative disorder 78.64 9.58 80 439939 2587 90185841
Polyomavirus viraemia 78.50 9.58 59 439960 1258 90187170
Gangrene 78.25 9.58 185 439834 12691 90175737
Full blood count abnormal 78.06 9.58 40 439979 36557 90151871
Urine ketone body present 77.90 9.58 78 439941 2474 90185954
Haemoglobin urine present 77.58 9.58 48 439971 734 90187694
Incorrect dose administered 76.73 9.58 168 439851 78762 90109666
Viral haemorrhagic cystitis 76.18 9.58 61 439958 1432 90186996
Rhabdomyolysis 75.86 9.58 82 439937 51174 90137254
Surgery 75.54 9.58 64 439955 44823 90143605
Multiple sclerosis 75.18 9.58 301 439718 27539 90160889
Red cell distribution width increased 74.85 9.58 176 439843 12031 90176397
Discomfort 74.72 9.58 912 439107 273423 89915005
Liver transplant rejection 74.43 9.58 64 439955 1664 90186764
Grip strength decreased 74.08 9.58 731 439288 91845 90096583
Neurologic neglect syndrome 73.16 9.58 144 439875 8703 90179725
Stenotrophomonas infection 73.00 9.58 75 439944 2454 90185974
Drug intolerance 72.69 9.58 1637 438382 445954 89742474
Disseminated aspergillosis 72.16 9.58 39 439980 455 90187973
Candida infection 71.93 9.58 342 439677 33715 90154713
Respiratory rate increased 71.62 9.58 205 439814 15796 90172632
Pain 71.50 9.58 4034 435985 992307 89196121
Substance-induced psychotic disorder 71.07 9.58 79 439940 2833 90185595
International normalised ratio increased 70.80 9.58 75 439944 47241 90141187
Carotid artery thrombosis 70.42 9.58 144 439875 8948 90179480
Strongyloidiasis 70.36 9.58 60 439959 1542 90186886
Plasma cell myeloma 70.21 9.58 57 439962 40771 90147657
COVID-19 pneumonia 70.14 9.58 221 439798 17956 90170472
Sensory loss 69.97 9.58 220 439799 17855 90170573
Transient ischaemic attack 69.72 9.58 64 439955 43112 90145316
Epilepsy 68.17 9.58 654 439365 81552 90106876
Protein urine present 68.12 9.58 122 439897 6862 90181566
Bone pain 67.92 9.58 123 439896 61860 90126568
Finger deformity 67.78 9.58 328 439691 32569 90155859
Intentional product use issue 67.69 9.58 1452 438567 215440 89972988
Atrial fibrillation 67.18 9.58 377 439642 133234 90055194
Full blood count decreased 67.07 9.58 30 439989 29659 90158769
Joint range of motion decreased 67.03 9.58 977 439042 134666 90053762
Perinephric abscess 66.94 9.58 32 439987 282 90188146
Dry skin 66.92 9.58 212 439807 87861 90100567
Coordination abnormal 66.82 9.58 242 439777 21114 90167314
Unevaluable event 66.45 9.58 102 439917 54746 90133682
Device malfunction 66.38 9.58 11 440008 20966 90167462
Device dislocation 66.27 9.58 35 439984 31447 90156981
Culture urine positive 65.93 9.58 87 439932 3738 90184690
Disseminated intravascular coagulation 65.65 9.58 242 439777 21296 90167132
Type 2 diabetes mellitus 65.48 9.58 1367 438652 201877 89986551
Accidental overdose 64.77 9.58 28 439991 28245 90160183
Electric shock 64.65 9.58 59 439960 1663 90186765
Lupus nephritis 64.15 9.58 97 439922 4735 90183693
Red blood cell sedimentation rate abnormal 63.91 9.58 19 440000 24185 90164243
Renal transplant failure 63.70 9.58 49 439970 1083 90187345
Electrocardiogram QT prolonged 63.44 9.58 163 439856 72293 90116135
Arthropathy 63.33 9.58 1326 438693 364916 89823512
Product storage error 63.19 9.58 11 440008 20230 90168198
Device difficult to use 63.18 9.58 6 440013 17519 90170909
Breast cancer 62.27 9.58 103 439916 53658 90134770
Central nervous system viral infection 62.11 9.58 25 439994 138 90188290
Pleocytosis 61.97 9.58 46 439973 962 90187466
Rash erythematous 61.63 9.58 533 439486 64571 90123857
Decreased appetite 61.44 9.58 1376 438643 375164 89813264
Liver function test increased 60.74 9.58 655 439364 84200 90104228
Subcutaneous drug absorption impaired 60.11 9.58 173 439846 13372 90175056
Specific gravity urine decreased 59.28 9.58 41 439978 764 90187664
Peripheral venous disease 59.24 9.58 646 439373 83275 90105153
Injection site mass 58.95 9.58 17 440002 22073 90166355
Cerebral aspergillosis 58.84 9.58 36 439983 539 90187889
Unresponsive to stimuli 58.65 9.58 59 439960 38062 90150366
Loss of personal independence in daily activities 58.59 9.58 403 439616 135702 90052726
Cystitis haemorrhagic 58.57 9.58 100 439919 5413 90183015
Lung disorder 58.46 9.58 1038 438981 148845 90039583
Neutrophil count increased 58.37 9.58 217 439802 19173 90169255
Adjustment disorder 58.01 9.58 138 439881 9504 90178924
Acute graft versus host disease 57.85 9.58 99 439920 5369 90183059
Hypophagia 57.17 9.58 54 439965 35883 90152545
Intra-abdominal pressure increased 57.04 9.58 28 439991 263 90188165
Foetal death 56.71 9.58 225 439794 20498 90167930
Urticaria 56.45 9.58 1950 438069 310784 89877644
Lethargy 56.08 9.58 141 439878 62998 90125430
Thrombocytopenia 56.00 9.58 1368 438651 207357 89981071
Sedation complication 55.63 9.58 8 440011 16936 90171492
Toxoplasmosis 55.30 9.58 55 439964 1730 90186698
Feeling abnormal 55.12 9.58 532 439487 166703 90021725
JC virus infection 55.04 9.58 67 439952 2652 90185776
Ureaplasma infection 54.96 9.58 41 439978 864 90187564
Pregnancy 54.77 9.58 139 439880 61908 90126520
Anaemia 54.53 9.58 1300 438719 351502 89836926
Taste disorder 54.21 9.58 496 439523 61050 90127378
Infective aneurysm 54.19 9.58 31 439988 407 90188021
Dizziness 54.02 9.58 2325 437694 586959 89601469
Epstein-Barr virus infection reactivation 53.62 9.58 52 439967 1585 90186843
Injection site haemorrhage 53.26 9.58 36 439983 28282 90160146
Parvovirus B19 infection 53.26 9.58 42 439977 964 90187464
Staphylococcal bacteraemia 52.85 9.58 114 439905 7355 90181073
Myalgia 52.81 9.58 569 439450 174556 90013872
Sleep disorder due to general medical condition, insomnia type 52.50 9.58 387 439632 128307 90060121
Metastases to liver 52.36 9.58 38 439981 28769 90159659
Swollen tongue 52.35 9.58 89 439930 45867 90142561
Needle issue 52.35 9.58 4 440015 13930 90174498
Immune thrombocytopenia 52.32 9.58 163 439856 13163 90175265
Protothecosis 52.10 9.58 31 439988 440 90187988
Gastroenteritis rotavirus 52.03 9.58 25 439994 223 90188205
Rash vesicular 51.77 9.58 200 439819 17997 90170431
Hypokalaemia 51.73 9.58 398 439621 130718 90057710
Body temperature decreased 51.64 9.58 241 439778 23575 90164853
Injection site warmth 51.55 9.58 11 440008 17504 90170924
Chorioretinopathy 51.52 9.58 39 439980 841 90187587
Schizophrenia 51.47 9.58 6 440013 14908 90173520
Candida sepsis 51.34 9.58 51 439968 1602 90186826
Intensive care unit acquired weakness 50.94 9.58 41 439978 970 90187458
Injection site rash 50.70 9.58 27 439992 24146 90164282
Intervertebral discitis 50.70 9.58 84 439935 4436 90183992
Nitrite urine present 50.67 9.58 42 439977 1037 90187391
Hepatitis 50.15 9.58 545 439474 70194 90118234
Liver injury 50.06 9.58 1132 438887 169435 90018993
Neuroleptic malignant syndrome 49.86 9.58 7 440012 15089 90173339
Infection reactivation 49.72 9.58 54 439965 1886 90186542
Somnolence 49.64 9.58 715 439304 208369 89980059
Bacteraemia 49.34 9.58 227 439792 22073 90166355
Disseminated tuberculosis 49.26 9.58 70 439949 3229 90185199
Hyperkalaemia 48.91 9.58 157 439862 64807 90123621
Gastroenteritis norovirus 48.83 9.58 59 439960 2317 90186111
Premature delivery 48.73 9.58 339 439680 38423 90150005
Hemiparesis 48.41 9.58 292 439727 31527 90156901
Encephalitis 48.24 9.58 141 439878 10993 90177435
Flatulence 48.15 9.58 79 439940 41288 90147140
Red blood cells urine 48.09 9.58 31 439988 511 90187917
Hemiplegia 47.94 9.58 180 439839 15980 90172448
Acute graft versus host disease in liver 47.80 9.58 36 439983 770 90187658
Metastases to bone 47.20 9.58 33 439986 25472 90162956
Hallucination 47.19 9.58 163 439856 65796 90122632
Human bocavirus infection 46.90 9.58 29 439990 443 90187985
Staphylococcal sepsis 46.73 9.58 125 439894 9258 90179170
Contusion 46.55 9.58 899 439120 250317 89938111
Coma 46.42 9.58 188 439831 72444 90115984
Torsade de pointes 45.79 9.58 9 440010 15173 90173255
Liver function test abnormal 45.58 9.58 113 439906 50732 90137696
Abortion spontaneous 45.50 9.58 124 439895 53932 90134496
Sneezing 45.37 9.58 274 439745 29595 90158833
Medication error 45.23 9.58 234 439785 84418 90104010
Malacoplakia 45.15 9.58 25 439994 307 90188121
Glossodynia 44.79 9.58 1204 438815 320575 89867853
Penicillium infection 44.78 9.58 24 439995 275 90188153
Product label confusion 44.35 9.58 224 439795 22626 90165802
Pulmonary hypertension 44.29 9.58 87 439932 42436 90145992
Injection site urticaria 44.28 9.58 16 440003 17995 90170433
Drug resistance 44.16 9.58 276 439743 30173 90158255
Pustular psoriasis 44.14 9.58 193 439826 18363 90170065
Rash pruritic 44.07 9.58 227 439792 81987 90106441
Human herpesvirus 8 infection 43.94 9.58 26 439993 365 90188063
Upper respiratory tract infection 43.93 9.58 871 439148 127447 90060981
Feeling hot 43.86 9.58 575 439444 77433 90110995
Immunosuppressant drug level decreased 43.58 9.58 40 439979 1136 90187292
Pain in jaw 43.52 9.58 106 439913 47879 90140549
Peripheral swelling 43.40 9.58 1604 438415 411502 89776926
Cerebrovascular accident 43.27 9.58 387 439632 123146 90065282
Cytomegalovirus chorioretinitis 43.22 9.58 56 439963 2363 90186065
Chronic obstructive pulmonary disease 42.96 9.58 198 439821 73631 90114797
Breast cancer stage III 42.80 9.58 611 439408 83836 90104592
Serum sickness 42.68 9.58 68 439951 3474 90184954
Monocyte percentage increased 42.66 9.58 40 439979 1168 90187260
Breast cancer female 42.50 9.58 10 440009 14876 90173552
Secondary immunodeficiency 42.41 9.58 52 439967 2074 90186354
Optic neuritis 42.36 9.58 123 439896 9555 90178873
Symptom masked 42.33 9.58 37 439982 984 90187444
Coronary artery disease 42.21 9.58 61 439958 33562 90154866
Monocyte count increased 42.13 9.58 118 439901 8979 90179449
Heart transplant rejection 42.04 9.58 34 439985 810 90187618
Blood pressure systolic decreased 41.72 9.58 119 439900 9151 90179277
Product prescribing error 41.60 9.58 51 439968 30094 90158334
Sepsis 41.39 9.58 1155 438864 178659 90009769
Myositis 40.99 9.58 228 439791 23900 90164528
Encephalitis autoimmune 40.51 9.58 50 439969 2008 90186420
Poor venous access 40.44 9.58 195 439824 19332 90169096
Nightmare 40.35 9.58 28 439991 21697 90166731
Granulomatosis with polyangiitis 40.31 9.58 56 439963 2529 90185899
Thyroxine free increased 40.15 9.58 36 439983 991 90187437
Pyelonephritis fungal 40.01 9.58 20 439999 196 90188232
General symptom 39.93 9.58 159 439860 14509 90173919
Obstructive airways disorder 39.84 9.58 40 439979 25829 90162599
Personality disorder 39.77 9.58 142 439877 12302 90176126
Facet joint syndrome 39.65 9.58 685 439334 97704 90090724
Pyrexia 39.64 9.58 3722 436297 656763 89531665
Cryptococcosis 39.55 9.58 42 439977 1429 90186999
Glomerulonephritis 39.25 9.58 54 439965 2416 90186012
Pneumonia bacterial 39.22 9.58 144 439875 12646 90175782
Retinitis 39.13 9.58 320 439699 38138 90150290
Nephropathy toxic 39.04 9.58 143 439876 12545 90175883
Neoplasm progression 39.00 9.58 100 439919 44386 90144042
West Nile viral infection 39.00 9.58 27 439992 504 90187924
Blood thyroid stimulating hormone decreased 38.78 9.58 86 439933 5654 90182774
Tardive dyskinesia 38.73 9.58 4 440015 10926 90177502
Intestinal obstruction 38.64 9.58 76 439943 37055 90151373
Pneumonia necrotising 38.60 9.58 29 439990 618 90187810
Therapy partial responder 38.59 9.58 210 439809 21833 90166595
Necrotising herpetic retinopathy 38.53 9.58 17 440002 122 90188306
Type I hypersensitivity 38.52 9.58 71 439948 4084 90184344
Scedosporium infection 38.47 9.58 32 439987 794 90187634
Seronegative arthritis 38.43 9.58 183 439836 18051 90170377
Gait inability 38.40 9.58 957 439062 145499 90042929
Motor dysfunction 38.37 9.58 190 439829 19040 90169388
Poisoning 38.30 9.58 13 440006 15204 90173224
Proteus infection 38.28 9.58 42 439977 1484 90186944
Drug dose omission by device 38.26 9.58 3 440016 10228 90178200
Steroid dependence 38.17 9.58 51 439968 2218 90186210
Demyelination 38.11 9.58 106 439913 8034 90180394
Segmental diverticular colitis 37.91 9.58 18 440001 156 90188272
Cataract 37.89 9.58 525 439494 71567 90116861
Deep vein thrombosis 37.61 9.58 275 439744 91345 90097083
Granuloma skin 37.61 9.58 4 440015 10676 90177752
Sleep apnoea syndrome 37.54 9.58 60 439959 31687 90156741
Labelled drug-drug interaction medication error 37.50 9.58 12 440007 14570 90173858
Blood parathyroid hormone decreased 37.36 9.58 7 440012 12209 90176219
Leukopenia 37.34 9.58 692 439327 100018 90088410
Pneumonia klebsiella 37.05 9.58 59 439960 3013 90185415
Sinus congestion 36.95 9.58 244 439775 27180 90161248
Vasculitis 36.94 9.58 212 439807 22481 90165947
Herpes virus infection 36.94 9.58 90 439929 6294 90182134
Central nervous system infection 36.68 9.58 32 439987 849 90187579
Acute myocardial infarction 36.67 9.58 71 439948 34819 90153609
Pedal pulse abnormal 36.44 9.58 19 440000 205 90188223
Drug withdrawal syndrome 36.17 9.58 52 439967 28671 90159757
Graft versus host disease in liver 36.16 9.58 33 439986 930 90187498
Epstein-Barr viraemia 36.08 9.58 40 439979 1430 90186998
Lip swelling 36.04 9.58 84 439935 38526 90149902
Breast cancer stage II 35.94 9.58 294 439725 35040 90153388
Drug tolerance decreased 35.89 9.58 63 439956 32067 90156361
Affect lability 35.71 9.58 178 439841 17885 90170543
Hypercalcaemia 35.71 9.58 70 439949 34170 90154258
Systemic lupus erythematosus 35.62 9.58 1416 438603 360480 89827948
Scleroderma renal crisis 35.61 9.58 24 439995 428 90188000
Throat tightness 35.39 9.58 255 439764 29229 90159199
Listeriosis 35.36 9.58 43 439976 1700 90186728
Right ventricular failure 35.34 9.58 25 439994 19180 90169248
Fracture 35.31 9.58 33 439986 22043 90166385
Brain abscess 35.29 9.58 55 439964 2757 90185671
Rash 34.99 9.58 3359 436660 792741 89395687
Product complaint 34.92 9.58 11 440008 13489 90174939
Cytomegalovirus enteritis 34.80 9.58 22 439997 350 90188078
Urinary tract candidiasis 34.75 9.58 29 439990 723 90187705
Pneumatosis 34.71 9.58 24 439995 447 90187981
Vaginal haemorrhage 34.31 9.58 62 439957 31209 90157219
Seizure 34.12 9.58 528 439491 152101 90036327
Nephrotic syndrome 33.80 9.58 95 439924 7244 90181184
Systemic inflammatory response syndrome 33.67 9.58 88 439931 6428 90182000
Adverse drug reaction 33.65 9.58 383 439636 116318 90072110
Confusional state 33.64 9.58 1532 438487 384673 89803755
Viraemia 33.58 9.58 41 439978 1628 90186800
Pneumocystis jirovecii infection 33.32 9.58 44 439975 1892 90186536
CSF oligoclonal band present 33.28 9.58 23 439996 428 90188000
Pneumonia acinetobacter 33.15 9.58 14 440005 89 90188339
Breast cancer metastatic 33.08 9.58 16 440003 15116 90173312
Infusion site reaction 33.07 9.58 181 439838 18858 90169570
Cells in urine 33.04 9.58 17 440002 178 90188250
Gastrointestinal mucormycosis 33.01 9.58 20 439999 294 90188134
Diverticulum 32.92 9.58 9 440010 12104 90176324
Chronic allograft nephropathy 32.91 9.58 29 439990 780 90187648
Dyskinesia 32.90 9.58 81 439938 36453 90151975
Chronic graft versus host disease 32.58 9.58 66 439953 4073 90184355
Vascular device infection 32.26 9.58 9 440010 11943 90176485
Dystonia 32.15 9.58 21 439998 16798 90171630
Thrombosis 31.96 9.58 216 439803 73035 90115393
Urine leukocyte esterase 31.91 9.58 16 440003 158 90188270
Mycoplasma test positive 31.89 9.58 15 440004 127 90188301
Proteinuria 31.85 9.58 208 439811 23083 90165345
Ankylosing spondylitis 31.72 9.58 12 440007 13121 90175307
Head injury 31.46 9.58 65 439954 31123 90157305
Tachycardia 31.45 9.58 995 439024 156678 90031750
Granulocyte count increased 31.38 9.58 38 439981 1496 90186932
Blood immunoglobulin M decreased 31.30 9.58 36 439983 1341 90187087
Infective pulmonary exacerbation of cystic fibrosis 31.20 9.58 6 440013 10273 90178155
Epistaxis 30.99 9.58 264 439755 84861 90103567
Feeding intolerance 30.97 9.58 31 439988 983 90187445
Disorientation 30.90 9.58 110 439909 44004 90144424
Paraesthesia ear 30.69 9.58 22 439997 435 90187993
Neuromyelitis optica spectrum disorder 30.62 9.58 37 439982 1453 90186975
Immune reconstitution inflammatory syndrome 30.52 9.58 89 439930 6930 90181498
Opportunistic infection 30.51 9.58 45 439974 2148 90186280
Lung neoplasm malignant 30.51 9.58 44 439975 24229 90164199
Dermatomyositis 30.51 9.58 57 439962 3313 90185115
Cholelithiasis 30.44 9.58 141 439878 52365 90136063
Haemolytic anaemia 30.41 9.58 125 439894 11572 90176856
Trichodysplasia spinulosa 30.17 9.58 26 439993 678 90187750
Calcium ionised decreased 30.09 9.58 20 439999 348 90188080
Device leakage 29.97 9.58 6 440013 9985 90178443
Cardiac disorder 29.94 9.58 158 439861 56714 90131714
Product substitution issue 29.91 9.58 26 439993 17982 90170446
Bacterial sepsis 29.90 9.58 71 439948 4884 90183544
Insomnia 29.81 9.58 1319 438700 332155 89856273
Hypofibrinogenaemia 29.77 9.58 35 439984 1335 90187093
Normal newborn 29.77 9.58 205 439814 23157 90165271
Central nervous system lymphoma 29.64 9.58 43 439976 2022 90186406
Mental status changes 29.60 9.58 114 439905 44565 90143863
Dislocation of vertebra 29.58 9.58 408 439611 55560 90132868
Metastases to central nervous system 29.53 9.58 25 439994 17517 90170911
Engraftment syndrome 29.51 9.58 26 439993 699 90187729
Creatinine renal clearance decreased 29.36 9.58 29 439990 18870 90169558
Therapeutic product effect decreased 29.29 9.58 1077 438942 276494 89911934
Dementia 29.26 9.58 44 439975 23817 90164611
Parkinsonism 29.07 9.58 16 440003 14049 90174379
Cardiac failure 29.03 9.58 366 439653 109130 90079298
Diffuse alveolar damage 28.98 9.58 31 439988 1064 90187364
Diffuse large B-cell lymphoma 28.79 9.58 100 439919 8545 90179883
Laryngeal stenosis 28.75 9.58 34 439985 1305 90187123
Haemoglobin urine 28.66 9.58 14 440005 130 90188298
Haemolytic uraemic syndrome 28.57 9.58 50 439969 2761 90185667
Febrile bone marrow aplasia 28.50 9.58 108 439911 9630 90178798
Hepatocellular injury 28.41 9.58 239 439780 28719 90159709
Laboratory test abnormal 28.24 9.58 106 439913 41748 90146680
Disseminated cryptococcosis 28.19 9.58 26 439993 743 90187685
Rhinitis allergic 28.16 9.58 24 439995 16761 90171667
Myelitis 27.99 9.58 42 439977 2036 90186392
Inflammation 27.92 9.58 1096 438923 177496 90010932
Atypical haemolytic uraemic syndrome 27.90 9.58 29 439990 962 90187466
Arthralgia 27.88 9.58 3332 436687 775190 89413238
Necrosis ischaemic 27.81 9.58 29 439990 966 90187462
Femur fracture 27.76 9.58 122 439897 45960 90142468
Pulmonary vasculitis 27.71 9.58 16 440003 214 90188214
Synovitis 27.71 9.58 1313 438706 328439 89859989
Irritability 27.68 9.58 85 439934 35577 90152851
Encephalitis cytomegalovirus 27.62 9.58 25 439994 697 90187731
Device breakage 27.58 9.58 17 440002 14027 90174401
Hypomagnesaemia 27.50 9.58 85 439934 35503 90152925
Enthesopathy 27.48 9.58 6 440013 9398 90179030
Oral pain 27.48 9.58 75 439944 32608 90155820
Blood immunoglobulin G decreased 27.36 9.58 56 439963 3482 90184946
Alternaria infection 27.33 9.58 19 440000 357 90188071
Engraft failure 27.29 9.58 19 440000 358 90188070
Interstitial lung disease 27.29 9.58 522 439497 75883 90112545
Focal segmental glomerulosclerosis 27.23 9.58 39 439980 1812 90186616
Chronic kidney disease 27.23 9.58 138 439881 50053 90138375
Overdose 27.21 9.58 571 439448 157138 90031290
Hypoaesthesia 27.20 9.58 1822 438197 312388 89876040
Mycotic endophthalmitis 27.17 9.58 15 440004 183 90188245
Dural arteriovenous fistula 27.15 9.58 9 440010 25 90188403
Body height decreased 27.11 9.58 12 440007 11937 90176491
Osteomyelitis fungal 27.04 9.58 10 440009 42 90188386
Malacoplakia vesicae 27.00 9.58 11 440008 63 90188365
Growth retardation 26.87 9.58 38 439981 1745 90186683
Dyspnoea exertional 26.85 9.58 223 439796 72065 90116363
Quadriparesis 26.77 9.58 46 439973 2503 90185925
Lip pruritus 26.70 9.58 33 439986 1327 90187101
Mycoplasma infection 26.59 9.58 27 439992 871 90187557
Sputum discoloured 26.59 9.58 36 439983 20355 90168073
Herpes simplex colitis 26.52 9.58 12 440007 92 90188336
Adverse reaction 26.44 9.58 240 439779 29472 90158956
Panniculitis 26.37 9.58 19 440000 14439 90173989
Jaundice cholestatic 26.30 9.58 8 440011 10035 90178393
Injection site induration 26.25 9.58 9 440010 10459 90177969
Monocyte count decreased 26.22 9.58 46 439973 2545 90185883
Intestinal perforation 26.19 9.58 135 439884 13746 90174682
Uterine perforation 26.17 9.58 3 440016 7551 90180877
Complication of device insertion 26.12 9.58 9 440010 10427 90178001
Laryngitis 26.02 9.58 368 439651 50385 90138043
Exposure during pregnancy 26.00 9.58 1411 438608 236999 89951429
Blood calcium increased 25.98 9.58 13 440006 12045 90176383
Neck pain 25.93 9.58 731 439288 113232 90075196
Shock haemorrhagic 25.88 9.58 123 439896 12122 90176306
Vesicoureteric reflux 25.82 9.58 17 440002 291 90188137
Emphysematous pyelonephritis 25.81 9.58 18 440001 340 90188088
Hypoproteinaemia 25.81 9.58 51 439968 3091 90185337
Haematemesis 25.74 9.58 81 439938 33645 90154783
Pulmonary tuberculosis 25.71 9.58 66 439953 4768 90183660
Aspergillosis oral 25.65 9.58 10 440009 50 90188378
Colitis microscopic 25.64 9.58 11 440008 11148 90177280
Eye pruritus 25.64 9.58 65 439954 28962 90159466
Hypocalcaemia 25.63 9.58 112 439907 42256 90146172
Prescribed overdose 25.60 9.58 638 439381 96987 90091441
Herpes zoster 25.57 9.58 621 439398 94023 90094405
Escherichia sepsis 25.53 9.58 74 439945 5742 90182686
Cytomegalovirus gastrointestinal infection 25.53 9.58 19 440000 399 90188029
Dysphagia 25.49 9.58 720 439299 111558 90076870
Muscle spasticity 25.43 9.58 273 439746 35049 90153379
Bronchial anastomosis complication 25.40 9.58 11 440008 75 90188353
Urinary casts 25.38 9.58 25 439994 777 90187651
Cytomegalovirus enterocolitis 25.38 9.58 26 439993 848 90187580
Product dispensing error 25.31 9.58 14 440005 12259 90176169
Hepatic steatosis 25.29 9.58 93 439926 36852 90151576
SARS-CoV-2 viraemia 25.29 9.58 9 440010 33 90188395
Band neutrophil percentage increased 25.26 9.58 15 440004 212 90188216
Bacillus infection 25.11 9.58 27 439992 932 90187496
Red blood cell count increased 25.09 9.58 55 439964 3588 90184840
Multiple allergies 24.99 9.58 22 439997 15124 90173304
Meningoencephalitis viral 24.98 9.58 18 440001 359 90188069
Nasopharyngitis 24.94 9.58 2298 437721 404806 89783622
Nephrolithiasis 24.93 9.58 138 439881 48947 90139481
Basal cell carcinoma 24.92 9.58 81 439938 33308 90155120
Myelopathy 24.86 9.58 53 439966 3391 90185037
Spondylitis 24.77 9.58 135 439884 14043 90174385
Complication associated with device 24.70 9.58 35 439984 19414 90169014
Pharyngeal dyskinesia 24.68 9.58 9 440010 36 90188392
Swelling face 24.64 9.58 264 439755 81088 90107340
Choroiditis 24.60 9.58 16 440003 268 90188160
Pre-existing condition improved 24.57 9.58 7 440012 9162 90179266
Abnormal dreams 24.46 9.58 12 440007 11245 90177183
Escherichia urinary tract infection 24.44 9.58 132 439887 13683 90174745
Cytokine release syndrome 24.41 9.58 225 439794 27748 90160680
Withdrawal syndrome 24.41 9.58 45 439974 22479 90165949
Multiple fractures 24.36 9.58 8 440011 9554 90178874
Bacterial infection 24.35 9.58 196 439823 23248 90165180
Cellulitis 24.32 9.58 305 439714 91032 90097396
Status epilepticus 24.27 9.58 166 439853 18708 90169720
Chronic graft versus host disease in skin 24.20 9.58 30 439989 1210 90187218
Hip fracture 24.16 9.58 81 439938 32996 90155432
CSF protein increased 23.95 9.58 24 439995 762 90187666
Meningomyelitis herpes 23.94 9.58 9 440010 40 90188388
Lip dry 23.93 9.58 651 439368 100304 90088124
Renal tubular atrophy 23.80 9.58 26 439993 914 90187514
Dysstasia 23.79 9.58 54 439965 24998 90163430
Pathogen resistance 23.75 9.58 90 439929 8025 90180403
Specific gravity urine increased 23.71 9.58 15 440004 239 90188189
Butterfly rash 23.70 9.58 40 439979 2145 90186283
JC polyomavirus test positive 23.68 9.58 36 439983 1766 90186662
Neuropsychiatric lupus 23.63 9.58 14 440005 197 90188231
Mean cell haemoglobin decreased 23.61 9.58 71 439948 5624 90182804
Anaphylactic shock 23.53 9.58 246 439773 31371 90157057
Blood immunoglobulin A increased 23.39 9.58 30 439989 1253 90187175
Respiratory arrest 23.37 9.58 83 439936 33228 90155200
Pemphigus 23.37 9.58 1323 438696 325541 89862887
Disseminated varicella zoster vaccine virus infection 23.37 9.58 10 440009 66 90188362
Cardio-respiratory arrest 23.35 9.58 195 439824 62945 90125483
Natural killer-cell leukaemia 23.30 9.58 11 440008 94 90188334
Rhinocerebral mucormycosis 23.29 9.58 24 439995 788 90187640
Secondary adrenocortical insufficiency 23.26 9.58 41 439978 2277 90186151
Corynebacterium infection 23.18 9.58 26 439993 942 90187486
B-lymphocyte count decreased 23.17 9.58 32 439987 1437 90186991
Immunosuppression 23.16 9.58 118 439901 11959 90176469
Hallucination, auditory 23.15 9.58 26 439993 15949 90172479
Dry throat 23.06 9.58 88 439931 7872 90180556
Pancreatitis 23.04 9.58 222 439797 69604 90118824
Rubella antibody positive 22.99 9.58 10 440009 69 90188359
Necrotising retinitis 22.97 9.58 20 439999 529 90187899
SARS-CoV-2 test positive 22.95 9.58 111 439908 11017 90177411
Mean cell haemoglobin concentration increased 22.95 9.58 21 439998 594 90187834
Hypertensive encephalopathy 22.91 9.58 23 439996 732 90187696
Hepatic infarction 22.86 9.58 22 439997 664 90187764
Listeria encephalitis 22.82 9.58 15 440004 256 90188172
Meningoencephalitis bacterial 22.82 9.58 15 440004 256 90188172
Chest pain 22.81 9.58 1294 438725 318351 89870077
Pyomyositis 22.76 9.58 18 440001 415 90188013
Oral herpes 22.71 9.58 256 439763 33268 90155160
Walking aid user 22.65 9.58 268 439751 35238 90153190
Akathisia 22.63 9.58 13 440006 11146 90177282
Mycobacterium abscessus infection 22.59 9.58 27 439992 1048 90187380
Peptostreptococcus infection 22.53 9.58 11 440008 102 90188326
Tri-iodothyronine free increased 22.52 9.58 14 440005 216 90188212
Cervicitis 22.38 9.58 20 439999 548 90187880
Congenital cytomegalovirus infection 22.35 9.58 12 440007 138 90188290
Anorectal ulcer 22.31 9.58 9 440010 50 90188378
Fluid retention 22.31 9.58 573 439446 87518 90100910
Disseminated blastomycosis 22.29 9.58 10 440009 75 90188353
Band sensation 22.29 9.58 28 439991 1145 90187283
Smear cervix abnormal 22.28 9.58 48 439971 3094 90185334
Blood cholesterol increased 22.26 9.58 1229 438790 206783 89981645
Product preparation error 22.21 9.58 11 440008 10250 90178178
Herpes simplex reactivation 22.09 9.58 26 439993 993 90187435
Blood lactate dehydrogenase decreased 22.08 9.58 14 440005 224 90188204
Blood potassium increased 22 9.58 42 439977 20707 90167721
Visceral leishmaniasis 21.98 9.58 21 439998 628 90187800
Oropharyngeal pain 21.95 9.58 723 439296 114464 90073964
Product administration error 21.95 9.58 61 439958 26362 90162066
Pulmonary haemorrhage 21.92 9.58 87 439932 7926 90180502
Osteoporosis 21.90 9.58 619 439400 95912 90092516
Non-consummation 21.88 9.58 9 440010 53 90188375
Obesity 21.88 9.58 669 439350 104838 90083590
Glomerulosclerosis 21.87 9.58 19 440000 501 90187927
Mitochondrial DNA mutation 21.87 9.58 18 440001 440 90187988
Blood glucose decreased 21.85 9.58 51 439968 23378 90165050
Tremor 21.85 9.58 571 439448 152602 90035826
Blood loss anaemia 21.75 9.58 11 440008 10129 90178299
Chronic graft versus host disease in liver 21.74 9.58 16 440003 330 90188098
Injection site discolouration 21.72 9.58 9 440010 9311 90179117
Urobilinogen urine increased 21.71 9.58 15 440004 279 90188149
Therapy non-responder 21.61 9.58 840 439179 135864 90052564
Nasal polyps 21.60 9.58 13 440006 10867 90177561
Joint tuberculosis 21.56 9.58 12 440007 149 90188279
Urinary retention 21.50 9.58 102 439917 37642 90150786
Hepatitis B 21.31 9.58 59 439960 4460 90183968
Alveolitis 21.25 9.58 46 439973 2975 90185453
Hairy cell leukaemia 21.24 9.58 7 440012 19 90188409
Renal vein thrombosis 21.19 9.58 20 439999 589 90187839
Extrapyramidal disorder 21.04 9.58 29 439990 16274 90172154
Enterococcus test positive 21.04 9.58 29 439990 1300 90187128
Exposure via skin contact 20.96 9.58 13 440006 10692 90177736
Graft versus host disease in lung 20.95 9.58 19 440000 531 90187897
Cerebellar stroke 20.95 9.58 17 440002 407 90188021
Factor XIII deficiency 20.93 9.58 10 440009 88 90188340
Thunderclap headache 20.86 9.58 16 440003 352 90188076
Product administration interrupted 20.79 9.58 18 440001 12474 90175954
Pulmonary embolism 20.74 9.58 480 439539 130340 90058088
Passenger lymphocyte syndrome 20.74 9.58 10 440009 90 90188338
Transfusion 20.72 9.58 33 439986 17455 90170973
Aplasia 20.72 9.58 54 439965 3937 90184491
Pruritus 20.72 9.58 2307 437712 539218 89649210
Anti-thyroid antibody positive 20.68 9.58 18 440001 476 90187952
Haemorrhage 20.65 9.58 226 439793 69143 90119285
Cerebral venous thrombosis 20.61 9.58 39 439980 2289 90186139
Rheumatic fever 20.60 9.58 925 439094 152196 90036232
CSF measles antibody positive 20.58 9.58 9 440010 63 90188365
Hand deformity 20.37 9.58 1204 438815 295158 89893270
Somnambulism 20.31 9.58 3 440016 6225 90182203
Asthenia 20.28 9.58 2275 437744 531476 89656952
Macular degeneration 20.26 9.58 105 439914 37865 90150563
Respiratory distress 20.21 9.58 283 439736 38663 90149765
Sensitivity to weather change 20.15 9.58 9 440010 8905 90179523
Ischaemic stroke 20.07 9.58 49 439970 22117 90166311
Central obesity 20.03 9.58 29 439990 1361 90187067
Muir-Torre syndrome 20.03 9.58 7 440012 24 90188404
Thirst 20.03 9.58 30 439989 16265 90172163
Partial seizures 20.01 9.58 79 439940 7181 90181247
Body temperature fluctuation 20.00 9.58 38 439981 2237 90186191
Transplant failure 19.98 9.58 35 439984 1934 90186494
Post cholecystectomy syndrome 19.97 9.58 23 439996 858 90187570
Aphthous ulcer 19.88 9.58 148 439871 17139 90171289
Cerebral artery stenosis 19.79 9.58 19 440000 572 90187856
Orbital apex syndrome 19.75 9.58 8 440011 45 90188383
Malignant catatonia 19.72 9.58 13 440006 223 90188205
Hypothyroidism 19.68 9.58 164 439855 52963 90135465
Disseminated varicella zoster virus infection 19.61 9.58 17 440002 447 90187981
Depressed mood 19.54 9.58 153 439866 50069 90138359
Cholecystectomy 19.49 9.58 17 440002 11738 90176690
Urinary tract infection bacterial 19.47 9.58 71 439948 6214 90182214
Blood brain barrier defect 19.46 9.58 11 440008 141 90188287
Meningitis staphylococcal 19.41 9.58 10 440009 105 90188323
Microangiopathy 19.41 9.58 32 439987 1683 90186745
Band neutrophil count increased 19.37 9.58 16 440003 393 90188035
Ageusia 19.37 9.58 30 439989 16046 90172382
Joint injury 19.36 9.58 87 439932 32577 90155851
Chorioretinitis 19.31 9.58 22 439997 811 90187617
Bronchiolitis obliterans syndrome 19.30 9.58 16 440003 395 90188033
Quadriplegia 19.28 9.58 37 439982 2194 90186234
Disseminated cytomegaloviral infection 19.10 9.58 14 440005 287 90188141
Stomatitis 19.06 9.58 1115 438904 273583 89914845
Angiosarcoma metastatic 19.05 9.58 9 440010 77 90188351
Cystitis 19.00 9.58 441 439578 66277 90122151
Blood albumin increased 18.97 9.58 26 439993 1159 90187269
Oral candidiasis 18.96 9.58 259 439760 35196 90153232
Eosinophil percentage increased 18.94 9.58 24 439995 990 90187438
Large intestine polyp 18.94 9.58 11 440008 9375 90179053
Sense of oppression 18.93 9.58 25 439994 1075 90187353
Palmar-plantar erythrodysaesthesia syndrome 18.88 9.58 71 439948 27952 90160476
Citrobacter infection 18.85 9.58 20 439999 680 90187748
Hyperglycaemia 18.81 9.58 350 439669 50620 90137808
Q fever 18.81 9.58 11 440008 151 90188277
Fungal endocarditis 18.74 9.58 15 440004 352 90188076
Birdshot chorioretinopathy 18.66 9.58 9 440010 81 90188347
Epstein-Barr virus associated lymphoma 18.66 9.58 20 439999 688 90187740
Muscle strain 18.64 9.58 12 440007 9675 90178753
Carotid artery occlusion 18.63 9.58 4 440015 6338 90182090
Dry mouth 18.63 9.58 1082 438937 182977 90005451
Atrioventricular block first degree 18.61 9.58 9 440010 8502 90179926
Multiple-drug resistance 18.59 9.58 81 439938 7695 90180733
Cestode infection 18.57 9.58 14 440005 300 90188128
Pulmonary arterial hypertension 18.54 9.58 65 439954 26122 90162306
Bacterial vulvovaginitis 18.47 9.58 22 439997 851 90187577
Renal disorder 18.39 9.58 108 439911 37751 90150677
Angioedema 18.28 9.58 214 439805 64662 90123766
Atrioventricular block 18.26 9.58 10 440009 8805 90179623
Asymptomatic bacteriuria 18.26 9.58 14 440005 308 90188120
Human polyomavirus infection 18.23 9.58 16 440003 428 90188000
Haemorrhagic varicella syndrome 18.22 9.58 5 440014 5 90188423
Haemostasis 18.14 9.58 15 440004 369 90188059
Acute respiratory failure 18.08 9.58 301 439718 42617 90145811
Renal graft infection 18.07 9.58 15 440004 371 90188057
Oropharyngeal discomfort 18.06 9.58 80 439939 7655 90180773
Ultrasound ovary abnormal 18.02 9.58 9 440010 88 90188340
Haemoglobin abnormal 17.98 9.58 6 440013 7094 90181334
Rhesus antigen positive 17.98 9.58 10 440009 124 90188304
Blood sodium decreased 17.94 9.58 71 439948 27542 90160886
Magnetic resonance imaging abnormal 17.93 9.58 47 439972 3439 90184989
Hiatus hernia 17.92 9.58 63 439956 25298 90163130
Eczema 17.91 9.58 167 439852 52703 90135725
Sinusitis 17.90 9.58 1428 438591 341660 89846768
Carpal tunnel syndrome 17.89 9.58 58 439961 23870 90164558
Meningitis cryptococcal 17.85 9.58 32 439987 1801 90186627
Spinal operation 17.82 9.58 14 440005 10182 90178246
Pain in extremity 17.80 9.58 1915 438104 448614 89739814
Thymoma 17.80 9.58 13 440006 265 90188163
Bronchospasm 17.78 9.58 166 439853 20543 90167885
Post-traumatic stress disorder 17.78 9.58 73 439946 6755 90181673
Graft loss 17.77 9.58 16 440003 443 90187985
Bundle branch block left 17.76 9.58 8 440011 7877 90180551
IgA nephropathy 17.68 9.58 22 439997 891 90187537
Myoclonus 17.65 9.58 42 439977 19126 90169302
Steroid withdrawal syndrome 17.65 9.58 19 440000 657 90187771
Acute myeloid leukaemia recurrent 17.64 9.58 34 439985 2023 90186405
Foetal exposure during pregnancy 17.63 9.58 129 439890 42846 90145582
Central nervous system lupus 17.58 9.58 27 439992 1336 90187092
Groin pain 17.56 9.58 20 439999 12193 90176235
Musculoskeletal disorder 17.53 9.58 51 439968 21718 90166710
White blood cells urine 17.50 9.58 16 440003 452 90187976
Corynebacterium sepsis 17.49 9.58 7 440012 38 90188390
Red blood cell sedimentation rate increased 17.47 9.58 525 439494 82070 90106358
Neutrophilic dermatosis 17.47 9.58 13 440006 273 90188155
Rheumatoid factor positive 17.43 9.58 669 439350 170981 90017447
Wound 17.40 9.58 1251 438768 301729 89886699
Blood potassium decreased 17.38 9.58 148 439871 47579 90140849
Fungal skin infection 17.38 9.58 61 439958 5240 90183188
Nerve injury 17.30 9.58 17 440002 11089 90177339
Osteoarthritis 17.28 9.58 1137 438882 194593 89993835
Pelvic pain 17.25 9.58 30 439989 15327 90173101
Acarodermatitis 17.24 9.58 27 439992 1359 90187069
Subcutaneous emphysema 17.20 9.58 24 439995 1088 90187340
Neutrophil count decreased 17.18 9.58 244 439775 71288 90117140
Pleural effusion 17.17 9.58 413 439606 111578 90076850
Oedema 17.12 9.58 796 439223 199499 89988929
Myelocyte count increased 17.10 9.58 15 440004 401 90188027
Phaeohyphomycosis 17.07 9.58 16 440003 467 90187961
Peripheral vascular disorder 17.07 9.58 5 440014 6426 90182002
Fungaemia 17.06 9.58 45 439974 3305 90185123
Urine oxalate increased 17.06 9.58 12 440007 230 90188198
Biliary anastomosis complication 17.05 9.58 7 440012 41 90188387
Staphylococcal infection 16.98 9.58 330 439689 48109 90140319
Dysgeusia 16.97 9.58 168 439851 52392 90136036
Myelocyte percentage increased 16.93 9.58 11 440008 184 90188244
Kidney fibrosis 16.85 9.58 35 439984 2199 90186229
Pneumonia adenoviral 16.84 9.58 12 440007 235 90188193
Pulmonary mass 16.83 9.58 77 439942 28695 90159733
Neoplasm malignant 16.80 9.58 96 439923 33784 90154644
Temperature intolerance 16.80 9.58 108 439911 11922 90176506
Heart rate irregular 16.75 9.58 186 439833 24082 90164346
Anti-cyclic citrullinated peptide antibody 16.72 9.58 204 439815 27017 90161411
Venous thrombosis 16.69 9.58 62 439957 5475 90182953
Leukocyturia 16.68 9.58 29 439990 1593 90186835
Mean cell volume decreased 16.67 9.58 54 439965 4452 90183976
Proctitis 16.63 9.58 129 439890 15130 90173298
Immunoglobulins decreased 16.63 9.58 29 439990 1597 90186831
Parvovirus infection 16.63 9.58 16 440003 483 90187945
Interleukin level increased 16.62 9.58 19 440000 703 90187725
Creatinine urine decreased 16.53 9.58 13 440006 297 90188131
Wrong technique in device usage process 16.50 9.58 4 440015 5831 90182597
Mean cell haemoglobin increased 16.49 9.58 49 439970 3856 90184572
Angina unstable 16.48 9.58 7 440012 7136 90181292
Neutropenic sepsis 16.48 9.58 40 439979 18090 90170338
Metastases to lung 16.41 9.58 33 439986 15958 90172470
Dysmenorrhoea 16.40 9.58 55 439964 4617 90183811
Endocrine toxicity 16.38 9.58 7 440012 46 90188382
Herpes simplex oesophagitis 16.38 9.58 11 440008 195 90188233
Cardiac arrest 16.36 9.58 386 439633 104549 90083879
Metabolic acidosis 16.33 9.58 182 439837 55494 90132934
Epidural lipomatosis 16.33 9.58 12 440007 247 90188181
Actinomycotic sepsis 16.29 9.58 12 440007 248 90188180
Scleritis 16.28 9.58 59 439960 5149 90183279
Ileus 16.26 9.58 35 439984 16511 90171917
Gastropleural fistula 16.26 9.58 7 440012 47 90188381
Varicella 16.24 9.58 36 439983 2366 90186062
Lichen sclerosus 16.20 9.58 26 439993 1337 90187091
Foot operation 16.19 9.58 12 440007 8989 90179439
Vein rupture 16.18 9.58 29 439990 1632 90186796
Kaposi's sarcoma 16.16 9.58 10 440009 153 90188275
Aspartate aminotransferase 16.13 9.58 19 440000 726 90187702
Fistula 16.11 9.58 21 439998 12068 90176360
Adrenal atrophy 16.01 9.58 7 440012 49 90188379
Ureteral disorder 16.00 9.58 14 440005 373 90188055
Tinnitus 15.99 9.58 133 439886 42969 90145459
Pelvic fracture 15.97 9.58 31 439988 15188 90173240
Papilloma viral infection 15.96 9.58 30 439989 1752 90186676
Tricuspid valve incompetence 15.94 9.58 36 439983 16695 90171733
Pulmonary interstitial emphysema syndrome 15.90 9.58 5 440014 11 90188417
Cardiac murmur 15.87 9.58 41 439978 18153 90170275
Hepatic cyst 15.87 9.58 6 440013 6562 90181866
Night sweats 15.84 9.58 771 439248 127995 90060433
Acute oesophageal mucosal lesion 15.81 9.58 9 440010 117 90188311
Adrenal insufficiency 15.76 9.58 218 439801 29703 90158725
Deafness congenital 15.74 9.58 9 440010 118 90188310
Obliterative bronchiolitis 15.73 9.58 38 439981 2643 90185785
Cryptococcal meningoencephalitis 15.72 9.58 10 440009 161 90188267
Faecal volume decreased 15.65 9.58 12 440007 264 90188164
Klebsiella test positive 15.62 9.58 27 439992 1476 90186952
Movement disorder 15.62 9.58 80 439939 28939 90159489
Limb mass 15.60 9.58 45 439974 3483 90184945
Neutropenia 15.57 9.58 913 439106 223991 89964437
Vaginal flatulence 15.57 9.58 110 439909 12528 90175900
pH urine increased 15.57 9.58 14 440005 387 90188041
Foetal growth restriction 15.51 9.58 88 439931 9292 90179136
Tri-iodothyronine free decreased 15.51 9.58 14 440005 389 90188039
Arterial intramural haematoma 15.45 9.58 10 440009 166 90188262
Hypoacusis 15.43 9.58 76 439943 27774 90160654
Diverticulum intestinal 15.42 9.58 13 440006 9129 90179299
Pneumonia aspiration 15.34 9.58 126 439893 40814 90147614
Cytomegalovirus hepatitis 15.33 9.58 14 440005 395 90188033
Intracranial infection 15.32 9.58 11 440008 218 90188210
Haemorrhoids 15.30 9.58 72 439947 26630 90161798
Hypocholesterolaemia 15.28 9.58 67 439952 6382 90182046
Donor specific antibody present 15.28 9.58 11 440008 219 90188209
Microscopic polyangiitis 15.24 9.58 11 440008 220 90188208
Japanese spotted fever 15.23 9.58 6 440013 31 90188397
Propofol infusion syndrome 15.17 9.58 25 439994 1314 90187114
Hepatic cyst infection 15.17 9.58 9 440010 127 90188301
Aspergilloma 15.16 9.58 12 440007 277 90188151
Ureteric stenosis 15.16 9.58 18 440001 694 90187734
Cystitis bacterial 15.12 9.58 13 440006 338 90188090
Proctitis haemorrhagic 15.11 9.58 4 440015 3 90188425
Atrial flutter 15.06 9.58 18 440001 10740 90177688
Leukoencephalopathy 15.06 9.58 55 439964 4818 90183610
Breast pain 15.05 9.58 17 440002 10401 90178027
Malaise 14.98 9.58 2559 437460 583427 89605001
Haemodynamic instability 14.95 9.58 103 439916 11636 90176792
Locked-in syndrome 14.95 9.58 15 440004 477 90187951
Enterocolitis viral 14.93 9.58 13 440006 344 90188084
Second primary malignancy 14.92 9.58 17 440002 10361 90178067
Colitis ischaemic 14.91 9.58 23 439996 12323 90176105
Condition aggravated 14.91 9.58 3189 436830 592356 89596072
Metastases to lymph nodes 14.88 9.58 21 439998 11668 90176760
Treatment noncompliance 14.81 9.58 170 439849 51557 90136871
Moyamoya disease 14.75 9.58 8 440011 94 90188334
Rectal haemorrhage 14.74 9.58 298 439721 82446 90105982
Anal erythema 14.73 9.58 12 440007 289 90188139
Gait disturbance 14.72 9.58 1077 438942 259419 89929009
Vision blurred 14.72 9.58 415 439604 109878 90078550
Serratia infection 14.72 9.58 22 439997 1063 90187365
Monocytosis 14.71 9.58 21 439998 973 90187455
Enterovirus infection 14.70 9.58 26 439993 1448 90186980
Pneumonia lipoid 14.70 9.58 9 440010 135 90188293
Antinuclear antibody 14.62 9.58 15 440004 490 90187938
Cancer in remission 14.61 9.58 7 440012 62 90188366
Allergy test positive 14.56 9.58 18 440001 724 90187704
Pyelonephritis 14.54 9.58 163 439856 21153 90167275
Skin striae 14.51 9.58 27 439992 1564 90186864
Intermenstrual bleeding 14.50 9.58 14 440005 9209 90179219
Paraparesis 14.49 9.58 39 439980 2899 90185529
Complications of transplanted lung 14.47 9.58 13 440006 359 90188069
Biloma 14.46 9.58 8 440011 98 90188330
Femoral neck fracture 14.45 9.58 17 440002 10216 90178212
Coronavirus infection 14.39 9.58 59 439960 5456 90182972
Complications of transplant surgery 14.38 9.58 10 440009 188 90188240
Encephalitis brain stem 14.36 9.58 9 440010 141 90188287
Diverticulitis 14.35 9.58 145 439874 45042 90143386
Infectious pleural effusion 14.33 9.58 30 439989 1895 90186533
Blindness cortical 14.28 9.58 16 440003 579 90187849
Dyschromatopsia 14.27 9.58 18 440001 739 90187689
Hyperferritinaemia 14.26 9.58 13 440006 366 90188062
Cryptococcal cutaneous infection 14.26 9.58 8 440011 101 90188327
Myelosuppression 14.25 9.58 179 439840 53412 90135016
Intestine transplant rejection 14.24 9.58 7 440012 66 90188362
Malacoplakia gastrointestinal 14.24 9.58 7 440012 66 90188362
Paralysis 14.20 9.58 100 439919 11378 90177050
Arteriovenous fistula 14.17 9.58 13 440006 369 90188059
Rhinovirus infection 14.17 9.58 62 439957 5901 90182527
Neuropsychiatric syndrome 14.15 9.58 7 440012 67 90188361
Body temperature increased 14.14 9.58 300 439719 44410 90144018
Rhodococcus infection 14.14 9.58 9 440010 145 90188283
Upper airway necrosis 14.10 9.58 6 440013 39 90188389
Acute disseminated encephalomyelitis 14.08 9.58 11 440008 249 90188179
Cellulitis staphylococcal 14.07 9.58 20 439999 923 90187505
Large intestine perforation 14.06 9.58 88 439931 9624 90178804
Bilirubin urine present 14.06 9.58 7 440012 68 90188360
Polyarthritis 14.05 9.58 44 439975 18306 90170122
Liver disorder 14.05 9.58 465 439554 120804 90067624
Back pain 14.05 9.58 1337 438682 315838 89872590
Device failure 14.03 9.58 8 440011 6889 90181539
Overlap syndrome 14.01 9.58 80 439939 8468 90179960
Lactic acidosis 14.00 9.58 167 439852 50296 90138132
Rheumatoid factor increased 13.96 9.58 34 439985 2377 90186051
Vein collapse 13.95 9.58 22 439997 1114 90187314
Capillary leak syndrome 13.92 9.58 37 439982 2730 90185698
Blastomycosis 13.91 9.58 14 440005 447 90187981
Thyroid stimulating immunoglobulin 13.88 9.58 7 440012 70 90188358
Sleep disorder due to general medical condition, hypersomnia type 13.88 9.58 31 439988 2048 90186380
Injection site extravasation 13.87 9.58 83 439936 8936 90179492
Eosinophil count abnormal 13.86 9.58 19 440000 847 90187581
Transient hypogammaglobulinaemia of infancy 13.84 9.58 6 440013 41 90188387
Hereditary angioedema 13.84 9.58 15 440004 9350 90179078
Presyncope 13.76 9.58 94 439925 31711 90156717
Aortitis salmonella 13.71 9.58 5 440014 20 90188408
Mean cell haemoglobin concentration decreased 13.70 9.58 50 439969 4378 90184050
Toxic shock syndrome staphylococcal 13.69 9.58 4 440015 6 90188422
Blood catecholamines abnormal 13.69 9.58 4 440015 6 90188422
Paraesthesia mucosal 13.69 9.58 4 440015 6 90188422
Lung abscess 13.67 9.58 32 439987 2181 90186247
Respiratory depression 13.66 9.58 35 439984 15540 90172888
Gastrointestinal mucosa hyperaemia 13.64 9.58 10 440009 205 90188223
Mucocutaneous leishmaniasis 13.63 9.58 13 440006 388 90188040
Dehiscence 13.62 9.58 9 440010 155 90188273
Suspected COVID-19 13.60 9.58 36 439983 2650 90185778
Exposure to SARS-CoV-2 13.59 9.58 34 439985 2418 90186010
Meningitis aseptic 13.57 9.58 67 439952 6706 90181722
Candida pneumonia 13.56 9.58 10 440009 207 90188221
Atrial septal defect 13.54 9.58 12 440007 8222 90180206
Human papilloma virus test positive 13.54 9.58 17 440002 695 90187733
Tuberculosis gastrointestinal 13.49 9.58 13 440006 393 90188035
Genital herpes 13.49 9.58 31 439988 2087 90186341
Lipaemic index score 13.47 9.58 7 440012 75 90188353
Injection site discomfort 13.42 9.58 6 440013 5934 90182494
Feeding disorder 13.41 9.58 42 439977 17470 90170958
Encephalitis Japanese B 13.37 9.58 6 440013 45 90188383
Hypertrichosis 13.37 9.58 25 439994 1454 90186974
Increased ventricular preload 13.34 9.58 5 440014 22 90188406
Palmar erythema 13.33 9.58 29 439990 1882 90186546
Premenstrual syndrome 13.31 9.58 18 440001 792 90187636
Pharyngeal disorder 13.31 9.58 34 439985 2449 90185979
Urogenital disorder 13.31 9.58 7 440012 77 90188351
Monoparesis 13.28 9.58 30 439989 1997 90186431
Aplastic anaemia 13.28 9.58 110 439909 13159 90175269
Ophthalmic herpes simplex 13.27 9.58 16 440003 627 90187801
Ulcer 13.27 9.58 229 439790 32653 90155775
Dengue fever 13.26 9.58 19 440000 883 90187545
Relapsing multiple sclerosis 13.23 9.58 10 440009 215 90188213
Chronic graft versus host disease in eye 13.20 9.58 10 440009 216 90188212
Myocardiac abscess 13.16 9.58 5 440014 23 90188405
Bundle branch block right 13.14 9.58 5 440014 5448 90182980
Product dose omission in error 13.14 9.58 53 439966 20450 90167978
Joint dislocation 13.10 9.58 296 439723 44286 90144142
Epiglottic erythema 13.08 9.58 7 440012 80 90188348
Injection site inflammation 13.06 9.58 3 440016 4538 90183890
Hypertriglyceridaemia 13.04 9.58 74 439945 7815 90180613
Extra dose administered 13.04 9.58 15 440004 9103 90179325
Liver abscess 13.03 9.58 42 439977 3454 90184974
Allergy to chemicals 13.01 9.58 44 439975 3710 90184718
Psychiatric decompensation 13.00 9.58 29 439990 1914 90186514
Parasitic pneumonia 13.00 9.58 3 440016 0 90188428
Cervical plexus lesion 13.00 9.58 3 440016 0 90188428
Central nervous system lesion 13.00 9.58 99 439920 11547 90176881
Blood gases abnormal 12.96 9.58 19 440000 902 90187526
Clubbing 12.96 9.58 14 440005 486 90187942
Abdominal pain 12.96 9.58 1703 438316 394018 89794410
Salivary hypersecretion 12.95 9.58 15 440004 9077 90179351
T-lymphocyte count decreased 12.95 9.58 12 440007 345 90188083
Herpes zoster meningoencephalitis 12.94 9.58 13 440006 414 90188014
Small intestinal obstruction 12.92 9.58 56 439963 21178 90167250
Pancreatic carcinoma 12.85 9.58 13 440006 8364 90180064
Influenza 12.84 9.58 812 439207 138452 90049976
Genital haemorrhage 12.79 9.58 14 440005 8688 90179740
Diabetic macroangiopathy 12.78 9.58 8 440011 125 90188303
Sickle cell anaemia with crisis 12.78 9.58 10 440009 7287 90181141
Fungal infection 12.78 9.58 284 439735 42377 90146051
Chronic graft versus host disease oral 12.77 9.58 10 440009 227 90188201
Enterocolitis bacterial 12.76 9.58 11 440008 287 90188141
Injection site haematoma 12.75 9.58 9 440010 6913 90181515
Expired product administered 12.75 9.58 9 440010 6913 90181515
Blood creatinine decreased 12.74 9.58 64 439955 6451 90181977
Thrombocytopenic purpura 12.71 9.58 28 439991 1833 90186595
Anger 12.68 9.58 30 439989 13690 90174738
Insurance issue 12.68 9.58 21 439998 10937 90177491
Dermatitis 12.68 9.58 60 439959 22160 90166268
Pneumoperitoneum 12.68 9.58 27 439992 1726 90186702
Hypertransaminasaemia 12.67 9.58 125 439894 15700 90172728
Delayed engraftment 12.67 9.58 8 440011 127 90188301
Right ventricle outflow tract obstruction 12.67 9.58 5 440014 26 90188402
Infected varicose vein 12.67 9.58 5 440014 26 90188402
Therapy change 12.66 9.58 13 440006 8309 90180119
Adjustment disorder with depressed mood 12.62 9.58 363 439656 56390 90132038
Low birth weight baby 12.61 9.58 84 439935 9383 90179045
Transfusion-related acute lung injury 12.60 9.58 9 440010 177 90188251
Lung transplant rejection 12.57 9.58 20 439999 1021 90187407
Pulse pressure increased 12.56 9.58 8 440011 129 90188299
Crying 12.54 9.58 73 439946 25572 90162856
Herpes simplex hepatitis 12.54 9.58 15 440004 583 90187845
Anogenital warts 12.54 9.58 15 440004 583 90187845
Cardiac pacemaker insertion 12.50 9.58 3 440016 4404 90184024
Arteriosclerosis coronary artery 12.47 9.58 17 440002 9586 90178842
Polychondritis 12.46 9.58 16 440003 669 90187759
Agitation 12.45 9.58 240 439779 66858 90121570
Febrile neutropenia 12.41 9.58 635 439384 157714 90030714
Fibromyalgia 12.41 9.58 1163 438856 205106 89983322
Back disorder 12.41 9.58 184 439835 25447 90162981
Abnormal loss of weight 12.40 9.58 9 440010 6814 90181614
Klebsiella sepsis 12.39 9.58 27 439992 1754 90186674
Procalcitonin increased 12.38 9.58 25 439994 1539 90186889
Ovarian fibroma 12.36 9.58 7 440012 90 90188338
Thyroid stimulating immunoglobulin increased 12.35 9.58 8 440011 133 90188295
Plasmodium falciparum infection 12.35 9.58 6 440013 55 90188373
Drug hypersensitivity 12.33 9.58 2020 437999 461589 89726839
Hepatitis toxic 12.33 9.58 43 439976 3682 90184746
Electric shock sensation 12.32 9.58 25 439994 1545 90186883
Stridor 12.29 9.58 51 439968 4742 90183686
Anti-neutrophil cytoplasmic antibody positive vasculitis 12.28 9.58 45 439974 3948 90184480
Hepatic enzyme 12.27 9.58 55 439964 5289 90183139
Eye haemorrhage 12.26 9.58 19 440000 10161 90178267
Parathyroid hyperplasia 12.25 9.58 8 440011 135 90188293
Hyperammonaemia 12.23 9.58 63 439956 6412 90182016
Alveolar proteinosis 12.22 9.58 18 440001 858 90187570
Lower respiratory tract congestion 12.22 9.58 40 439979 3316 90185112
Interleukin-2 receptor increased 12.20 9.58 8 440011 136 90188292
Excessive skin 12.20 9.58 8 440011 136 90188292
Reticulocytosis 12.20 9.58 10 440009 243 90188185
Fear of injection 12.18 9.58 14 440005 8501 90179927
Type 1 diabetes mellitus 12.18 9.58 51 439968 4761 90183667
Mitral valve incompetence 12.18 9.58 62 439957 22462 90165966
Ejection fraction decreased 12.17 9.58 76 439943 26177 90162251
Cytopenia 12.16 9.58 134 439885 17315 90171113
Poikiloderma 12.14 9.58 11 440008 307 90188121
Hepatitis C 12.07 9.58 57 439962 5603 90182825
Faecaloma 12.06 9.58 20 439999 10411 90178017
Meningitis listeria 12.06 9.58 16 440003 691 90187737
Appetite disorder 12.03 9.58 16 440003 9117 90179311
Tendonitis 12.03 9.58 58 439961 21314 90167114
Soft tissue disorder 12.02 9.58 3 440016 4287 90184141
Relapsing-remitting multiple sclerosis 12.00 9.58 17 440002 782 90187646
Pseudoaldosteronism 12.00 9.58 8 440011 140 90188288
Parosmia 11.99 9.58 10 440009 7059 90181369
Immunisation reaction 11.98 9.58 17 440002 783 90187645
Measles 11.97 9.58 12 440007 381 90188047
Aggression 11.95 9.58 78 439941 26590 90161838
Glomerulonephritis chronic 11.95 9.58 8 440011 141 90188287
Viral myelitis 11.94 9.58 5 440014 31 90188397
Herpes zoster infection neurological 11.93 9.58 14 440005 533 90187895
Acute lung injury 11.93 9.58 24 439995 1474 90186954
Meningitis fungal 11.91 9.58 7 440012 97 90188331
Glomerular filtration rate increased 11.87 9.58 29 439990 2031 90186397
Hepatic artery thrombosis 11.85 9.58 7 440012 98 90188330
Human herpesvirus 6 infection reactivation 11.83 9.58 15 440004 619 90187809
Gout 11.83 9.58 42 439977 16817 90171611
Adult T-cell lymphoma/leukaemia 11.83 9.58 10 440009 254 90188174
Anaphylactoid reaction 11.82 9.58 48 439971 4420 90184008
White blood cell count decreased 11.81 9.58 677 439342 166432 90021996
Skin discolouration 11.79 9.58 148 439871 44167 90144261
Glomerulonephritis membranous 11.78 9.58 16 440003 707 90187721
Muscle twitching 11.77 9.58 69 439950 24133 90164295
Hypokinesia 11.77 9.58 38 439981 15659 90172769
Galactorrhoea 11.74 9.58 4 440015 4668 90183760
Impaired work ability 11.74 9.58 51 439968 19275 90169153
Hepatic necrosis 11.72 9.58 62 439957 6376 90182052
Bradypnoea 11.69 9.58 4 440015 4654 90183774
Stent placement 11.66 9.58 3 440016 4200 90184228
Neurosarcoidosis 11.65 9.58 11 440008 324 90188104
Crystalluria 11.62 9.58 14 440005 548 90187880
Acute pulmonary oedema 11.58 9.58 83 439936 9497 90178931
Synovial fluid analysis 11.56 9.58 35 439984 2783 90185645
Nocturia 11.55 9.58 20 439999 10235 90178193
Magnesium deficiency 11.54 9.58 16 440003 721 90187707
Troponin increased 11.53 9.58 30 439989 13251 90175177
Venoocclusive disease 11.52 9.58 32 439987 2423 90186005
Euglycaemic diabetic ketoacidosis 11.51 9.58 8 440011 6193 90182235
Hypoalbuminaemia 11.50 9.58 123 439896 15774 90172654
Pneumonia pseudomonal 11.50 9.58 38 439981 3165 90185263
Human herpesvirus 6 encephalitis 11.48 9.58 12 440007 401 90188027
Congenital anomaly 11.47 9.58 61 439958 6286 90182142
Mycobacterium haemophilum infection 11.47 9.58 9 440010 205 90188223
Blood thyroid stimulating hormone increased 11.47 9.58 80 439939 9075 90179353
Respiratory tract congestion 11.46 9.58 192 439827 27218 90161210
Gastrointestinal viral infection 11.46 9.58 23 439996 1410 90187018
Ependymoma 11.43 9.58 7 440012 105 90188323
Incorrect drug administration rate 11.43 9.58 53 439966 5170 90183258
Central venous pressure increased 11.43 9.58 7 440012 105 90188323
Achromobacter infection 11.41 9.58 6 440013 66 90188362
Therapeutic response unexpected 11.39 9.58 61 439958 21819 90166609
Thrombotic thrombocytopenic purpura 11.38 9.58 45 439974 4093 90184335
Viral myocarditis 11.38 9.58 12 440007 405 90188023
Microsporidia infection 11.35 9.58 11 440008 335 90188093
Hypomania 11.31 9.58 16 440003 8881 90179547
Diabetes mellitus 11.30 9.58 403 439616 64472 90123956
Haemorrhagic stroke 11.25 9.58 9 440010 6487 90181941
Herpes simplex encephalitis 11.24 9.58 12 440007 411 90188017
Muscle rigidity 11.18 9.58 34 439985 14275 90174153
Sinus disorder 11.18 9.58 232 439787 34215 90154213
Plasmapheresis 11.16 9.58 11 440008 342 90188086
Urinary casts present 11.15 9.58 7 440012 110 90188318
Tension headache 11.12 9.58 12 440007 7497 90180931
Laryngeal mass 11.09 9.58 5 440014 38 90188390
Small intestine gangrene 11.09 9.58 5 440014 38 90188390
Impaired gastric emptying 11.07 9.58 29 439990 12780 90175648
Bone lesion 11.05 9.58 9 440010 6428 90182000
Hand dermatitis 11.04 9.58 14 440005 578 90187850
Linear IgA disease 11.03 9.58 30 439989 2244 90186184
Germ cell cancer 11.03 9.58 6 440013 71 90188357
Multisystem inflammatory syndrome in children 10.97 9.58 4 440015 16 90188412
Long QT syndrome 10.97 9.58 3 440016 4034 90184394
Focal nodular hyperplasia 10.97 9.58 16 440003 756 90187672
Sebaceous carcinoma 10.96 9.58 6 440013 72 90188356
Infusion site mobility decreased 10.96 9.58 6 440013 72 90188356
Pancreas transplant rejection 10.95 9.58 8 440011 163 90188265
Rheumatoid factor 10.95 9.58 13 440006 501 90187927
Skin haemorrhage 10.95 9.58 155 439864 21225 90167203
Injection site nodule 10.95 9.58 4 440015 4469 90183959
Faciobrachial dystonic seizure 10.93 9.58 3 440016 3 90188425
Bladder cancer recurrent 10.93 9.58 9 440010 220 90188208
Coxsackie myocarditis 10.93 9.58 3 440016 3 90188425
Meningitis chemical 10.92 9.58 10 440009 283 90188145
Eosinophilic granulomatosis with polyangiitis 10.92 9.58 32 439987 2498 90185930
Injury associated with device 10.92 9.58 4 440015 4460 90183968
Capillaritis 10.91 9.58 8 440011 164 90188264
Myasthenia gravis crisis 10.91 9.58 19 440000 1045 90187383
Secretion discharge 10.89 9.58 40 439979 15856 90172572
Bedridden 10.89 9.58 27 439992 12121 90176307
Tuberculosis of central nervous system 10.88 9.58 11 440008 353 90188075
Limbic encephalitis 10.87 9.58 10 440009 285 90188143
Skin irritation 10.86 9.58 32 439987 13571 90174857
Injection site irritation 10.85 9.58 8 440011 6007 90182421
Genital herpes simplex 10.82 9.58 12 440007 429 90187999
Immune effector cell-associated neurotoxicity syndrome 10.81 9.58 56 439963 5712 90182716
Joint destruction 10.79 9.58 31 439988 13256 90175172
Illness 10.79 9.58 309 439710 81660 90106768
Coma scale abnormal 10.79 9.58 7 440012 5619 90182809
Refractory anaemia with an excess of blasts 10.78 9.58 12 440007 431 90187997
Vascular rupture 10.77 9.58 26 439993 1807 90186621
Larynx irritation 10.75 9.58 8 440011 168 90188260
Vaginal discharge 10.74 9.58 143 439876 19321 90169107
Decreased immune responsiveness 10.70 9.58 76 439943 8672 90179756
Decreased interest 10.69 9.58 4 440015 4403 90184025
Drug eruption 10.68 9.58 115 439904 35292 90153136
Skin cancer 10.65 9.58 32 439987 13487 90174941
Complement factor C4 decreased 10.64 9.58 10 440009 293 90188135
Sexual dysfunction 10.62 9.58 5 440014 4799 90183629
B-lymphocyte count increased 10.62 9.58 7 440012 120 90188308
Bacillus bacteraemia 10.62 9.58 7 440012 120 90188308
Bipolar disorder 10.60 9.58 17 440002 8968 90179460
Idiopathic pneumonia syndrome 10.60 9.58 12 440007 439 90187989
Myocardial calcification 10.56 9.58 9 440010 231 90188197
Peritonitis 10.56 9.58 144 439875 19561 90168867
Lymphoedema 10.52 9.58 33 439986 13720 90174708
Melaena 10.50 9.58 113 439906 34684 90153744
Cutaneous mucormycosis 10.47 9.58 6 440013 79 90188349
Coinfection 10.47 9.58 5 440014 44 90188384
Stenotrophomonas sepsis 10.47 9.58 5 440014 44 90188384
Drug level decreased 10.46 9.58 82 439937 9648 90178780
Lung squamous cell carcinoma metastatic 10.43 9.58 4 440015 19 90188409
Lepromatous leprosy 10.43 9.58 4 440015 19 90188409
Osteomyelitis acute 10.42 9.58 10 440009 301 90188127
Aphasia 10.41 9.58 277 439742 42535 90145893
Heliotrope rash 10.40 9.58 9 440010 236 90188192
Product quality issue 10.40 9.58 478 439541 78847 90109581
Colorectal cancer 10.38 9.58 3 440016 3890 90184538
Pseudomonal bacteraemia 10.37 9.58 27 439992 1967 90186461
Lymphocele 10.37 9.58 16 440003 795 90187633
Ureteric obstruction 10.33 9.58 28 439991 2090 90186338
Angiocentric lymphoma 10.33 9.58 15 440004 706 90187722
Cutaneous lupus erythematosus 10.33 9.58 36 439983 3082 90185346
Respiratory tract oedema 10.31 9.58 15 440004 707 90187721
Pallor 10.29 9.58 111 439908 34054 90154374
Peliosis hepatis 10.28 9.58 7 440012 127 90188301
Complement factor C3 decreased 10.28 9.58 10 440009 306 90188122
Diffuse large B-cell lymphoma stage III 10.27 9.58 5 440014 46 90188382
Enterobacter pneumonia 10.27 9.58 5 440014 46 90188382
Aspartate aminotransferase increased 10.27 9.58 402 439617 102535 90085893
Lymphocyte count increased 10.26 9.58 43 439976 4016 90184412
Faeces discoloured 10.26 9.58 61 439958 21259 90167169
CD4 lymphocytes decreased 10.25 9.58 23 439996 1524 90186904
Organic brain syndrome 10.25 9.58 9 440010 241 90188187
Epigastric discomfort 10.24 9.58 13 440006 7555 90180873
Performance status decreased 10.19 9.58 4 440015 4276 90184152
Hepatosplenomegaly 10.19 9.58 35 439984 2974 90185454
Osteogenesis imperfecta 10.19 9.58 17 440002 903 90187525
Eastern Cooperative Oncology Group performance status 10.19 9.58 7 440012 129 90188299
Hyperoxaluria 10.17 9.58 8 440011 183 90188245
Intentional dose omission 10.16 9.58 48 439971 17735 90170693
Periostitis 10.16 9.58 12 440007 460 90187968
Bone marrow failure 10.13 9.58 216 439803 32005 90156423
Oropharyngeal plaque 10.10 9.58 10 440009 313 90188115
Myocarditis infectious 10.09 9.58 5 440014 48 90188380
Cognitive disorder 10.09 9.58 258 439761 69149 90119279
Tenosynovitis stenosans 10.09 9.58 42 439977 3911 90184517
Eye inflammation 10.07 9.58 69 439950 7782 90180646
Shock 10.06 9.58 196 439823 28582 90159846
Intervertebral disc protrusion 10.05 9.58 84 439935 27112 90161316
Chronic lymphocytic leukaemia recurrent 10.04 9.58 11 440008 388 90188040
Delusion 10.04 9.58 34 439985 13806 90174622
Tooth extraction 10.00 9.58 26 439993 11487 90176941
Hepatic function abnormal 10.00 9.58 295 439724 45993 90142435
Plasma cell myeloma recurrent 9.99 9.58 4 440015 4224 90184204
Tuberous sclerosis complex 9.97 9.58 6 440013 87 90188341
Gastrointestinal pain 9.97 9.58 25 439994 11181 90177247
Oesophageal candidiasis 9.96 9.58 62 439957 6767 90181661
Coagulation factor VIII level increased 9.95 9.58 4 440015 22 90188406
Allergy to plants 9.95 9.58 16 440003 824 90187604
Panic attack 9.94 9.58 81 439938 26284 90162144
Electrocardiogram abnormal 9.94 9.58 22 439997 10276 90178152
Tachypnoea 9.94 9.58 152 439867 21157 90167271
Secondary progressive multiple sclerosis 9.94 9.58 23 439996 1556 90186872
Hypersensitivity 9.93 9.58 2002 438017 452675 89735753
Feeling cold 9.93 9.58 188 439831 27277 90161151
Scleral thinning 9.92 9.58 5 440014 50 90188378
Dermatofibrosarcoma protuberans 9.92 9.58 5 440014 50 90188378
Drug level below therapeutic 9.92 9.58 55 439964 5759 90182669
Eructation 9.90 9.58 24 439995 10858 90177570
Muscle abscess 9.88 9.58 11 440008 395 90188033
Dysphonia 9.85 9.58 232 439787 62852 90125576
Disturbance in attention 9.84 9.58 165 439854 46944 90141484
Parainfluenzae virus infection 9.84 9.58 33 439986 2770 90185658
Fracture pain 9.84 9.58 19 440000 1132 90187296
Thyroxine free decreased 9.84 9.58 16 440003 832 90187596
Hypercreatininaemia 9.83 9.58 15 440004 738 90187690
Gastritis 9.82 9.58 143 439876 41610 90146818
Histoplasmosis disseminated 9.80 9.58 29 439990 2276 90186152
Globulins decreased 9.80 9.58 11 440008 399 90188029
Aspergillus test positive 9.80 9.58 11 440008 399 90188029
Blood magnesium decreased 9.79 9.58 41 439978 15652 90172776
Upper-airway cough syndrome 9.78 9.58 39 439980 15096 90173332
Drug dependence 9.78 9.58 93 439926 29234 90159194
Complications of transplanted liver 9.77 9.58 11 440008 400 90188028
Creatinine urine increased 9.76 9.58 9 440010 257 90188171
Hepatic haemorrhage 9.75 9.58 14 440005 652 90187776
Pneumonia fungal 9.74 9.58 63 439956 6968 90181460
Initial insomnia 9.74 9.58 19 440000 9291 90179137
Haemangioma-thrombocytopenia syndrome 9.73 9.58 3 440016 6 90188422
Skin hyperplasia 9.73 9.58 3 440016 6 90188422
Osseous cryptococcosis 9.73 9.58 3 440016 6 90188422
Anaphylactic reaction 9.73 9.58 519 439500 87005 90101423
Incorrect route of product administration 9.72 9.58 180 439839 50446 90137982
Beta 2 microglobulin increased 9.71 9.58 9 440010 259 90188169
Red cell distribution width decreased 9.70 9.58 28 439991 2168 90186260
Reticulocytopenia 9.68 9.58 6 440013 92 90188336
Disseminated mucormycosis 9.67 9.58 14 440005 657 90187771
Granulicatella bacteraemia 9.66 9.58 4 440015 24 90188404
Oral discomfort 9.63 9.58 23 439996 10460 90177968
Monocyte percentage decreased 9.62 9.58 9 440010 262 90188166
Cytokine storm 9.61 9.58 13 440006 572 90187856
Escherichia bacteraemia 9.61 9.58 54 439965 5681 90182747
Gastric ulcer 9.60 9.58 86 439933 27362 90161066
Catheter site infection 9.59 9.58 8 440011 5646 90182782
Polycystic ovaries 9.59 9.58 8 440011 5646 90182782

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 1898.60 10.50 6912 193273 631423 41789727
Cytomegalovirus infection 1067.61 10.50 1015 199170 31291 42389859
Drug ineffective for unapproved indication 843.96 10.50 1062 199123 45101 42376049
Drug ineffective 712.09 10.50 5216 194969 624981 41796169
Transplant rejection 585.34 10.50 496 199689 13092 42408058
Death 536.29 10.50 869 199316 470316 41950834
Infusion related reaction 409.27 10.50 891 199294 59915 42361235
Aspergillus infection 406.20 10.50 434 199751 15403 42405747
Multiple organ dysfunction syndrome 402.49 10.50 1183 199002 95852 42325298
Pneumocystis jirovecii pneumonia 400.28 10.50 541 199644 24640 42396510
Post transplant lymphoproliferative disorder 399.13 10.50 336 199849 8784 42412366
Completed suicide 368.04 10.50 21 200164 96444 42324706
Drug abuse 367.76 10.50 34 200151 104737 42316413
Cytomegalovirus viraemia 357.78 10.50 334 199851 10043 42411107
Bronchopulmonary aspergillosis 356.40 10.50 448 199737 18981 42402169
Respiratory failure 342.28 10.50 1348 198837 126784 42294366
Epstein-Barr virus infection 341.25 10.50 316 199869 9402 42411748
Kidney transplant rejection 339.61 10.50 300 199885 8383 42412767
Mucormycosis 333.02 10.50 273 199912 6870 42414280
Strongyloidiasis 332.58 10.50 205 199980 3226 42417924
Septic shock 330.16 10.50 1064 199121 90608 42330542
Polyomavirus-associated nephropathy 318.69 10.50 241 199944 5374 42415776
Graft versus host disease 301.53 10.50 337 199848 12588 42408562
Posterior reversible encephalopathy syndrome 300.32 10.50 335 199850 12486 42408664
Fall 296.53 10.50 401 199784 234119 42187031
Product use in unapproved indication 293.31 10.50 1669 198516 182787 42238363
Thrombotic microangiopathy 287.42 10.50 351 199834 14431 42406719
Toxicity to various agents 280.47 10.50 401 199784 228735 42192415
Fatigue 276.45 10.50 1083 199102 434558 41986592
Product dose omission issue 274.65 10.50 195 199990 154170 42266980
Enterococcal infection 270.78 10.50 308 199877 11731 42409419
Blood pressure diastolic abnormal 248.22 10.50 216 199969 5912 42415238
Cytomegalovirus infection reactivation 243.02 10.50 281 199904 10897 42410253
Acute graft versus host disease in skin 235.09 10.50 228 199957 7196 42413954
Nausea 234.33 10.50 1014 199171 395785 42025365
Blood pressure fluctuation 233.02 10.50 438 199747 26470 42394680
Adenovirus infection 226.75 10.50 215 199970 6594 42414556
Dizziness 221.72 10.50 530 199655 248724 42172426
Complications of transplanted kidney 217.55 10.50 189 199996 5161 42415989
Haemophagocytic lymphohistiocytosis 213.37 10.50 339 199846 17883 42403267
BK virus infection 208.27 10.50 231 199954 8553 42412597
Nocardiosis 206.32 10.50 181 200004 5009 42416141
Blood pressure systolic abnormal 198.43 10.50 182 200003 5346 42415804
Blood pressure systolic increased 193.95 10.50 415 199770 27553 42393597
Drug effective for unapproved indication 192.03 10.50 194 199991 6439 42414711
Pneumatosis intestinalis 191.47 10.50 167 200018 4585 42416565
Candida infection 189.89 10.50 354 199831 21256 42399894
Pulmonary nocardiosis 187.76 10.50 113 200072 1699 42419451
Pseudomonas infection 187.50 10.50 297 199888 15626 42405524
Intentional overdose 182.37 10.50 16 200169 51440 42369710
Hospitalisation 180.17 10.50 62 200123 74268 42346882
Steroid diabetes 174.34 10.50 128 200057 2724 42418426
Graft versus host disease in gastrointestinal tract 172.41 10.50 163 200022 4980 42416170
Cytomegalovirus test positive 170.44 10.50 150 200035 4169 42416981
Constipation 168.50 10.50 316 199869 161975 42259175
Oxygen saturation decreased 167.20 10.50 674 199511 64013 42357137
Myocardial infarction 166.90 10.50 202 199983 123807 42297343
Pneumonia cytomegaloviral 166.24 10.50 145 200040 3981 42417169
Syncope 162.19 10.50 137 200048 99269 42321881
Klebsiella infection 161.39 10.50 231 199954 11101 42410049
Disseminated intravascular coagulation 159.53 10.50 357 199828 24437 42396713
Cystitis haemorrhagic 152.24 10.50 180 200005 7149 42414001
Acute respiratory distress syndrome 150.27 10.50 393 199792 29715 42391435
Cardiac failure congestive 149.70 10.50 110 200075 85492 42335658
Rebound effect 149.60 10.50 179 200006 7200 42413950
Acute graft versus host disease in liver 147.85 10.50 100 200085 1858 42419292
Acute graft versus host disease in intestine 145.57 10.50 132 200053 3819 42417331
Cytomegalovirus colitis 144.71 10.50 132 200053 3849 42417301
Overdose 144.26 10.50 169 200016 105095 42316055
Dehydration 143.67 10.50 280 199905 141487 42279663
Parvovirus B19 infection 141.64 10.50 93 200092 1641 42419509
Pneumomediastinum 140.87 10.50 117 200068 2999 42418151
Acute graft versus host disease 140.50 10.50 183 200002 8032 42413118
Asthenia 140.17 10.50 761 199424 280032 42141118
Vomiting 136.61 10.50 800 199385 288923 42132227
Graft versus host disease in skin 132.15 10.50 142 200043 5070 42416080
Disseminated mucormycosis 131.99 10.50 82 200103 1309 42419841
Injection site pain 130.38 10.50 54 200131 57744 42363406
Heart rate decreased 125.93 10.50 418 199767 36114 42385036
Cerebrovascular accident 125.75 10.50 163 200022 96997 42324153
Therapy non-responder 125.35 10.50 540 199645 52819 42368331
Condition aggravated 124.57 10.50 1815 198370 258939 42162211
Diarrhoea 122.31 10.50 1482 198703 459367 41961783
Disease recurrence 122.04 10.50 361 199824 29317 42391833
Infection reactivation 119.73 10.50 92 200093 2102 42419048
Cushingoid 119.59 10.50 111 200074 3311 42417839
Chronic allograft nephropathy 116.83 10.50 80 200105 1518 42419632
Depression 115.37 10.50 217 199968 111146 42310004
Immunosuppressant drug level increased 113.64 10.50 160 200025 7571 42413579
Human herpesvirus 6 infection 112.47 10.50 94 200091 2431 42418719
Suicide attempt 109.05 10.50 40 200145 46060 42375090
Chronic graft versus host disease 107.40 10.50 137 200048 5888 42415262
Hypogammaglobulinaemia 107.23 10.50 197 199988 11694 42409456
Coronary artery disease 106.23 10.50 60 200125 53660 42367490
Blood pressure increased 103.03 10.50 825 199360 101103 42320047
Lymphocyte count decreased 102.89 10.50 326 199859 27483 42393667
Bacterial sepsis 102.55 10.50 139 200046 6343 42414807
Wrong technique in product usage process 99.16 10.50 38 200147 42597 42378553
Delayed graft function 98.98 10.50 89 200096 2546 42418604
Cryptococcosis 98.64 10.50 97 200088 3114 42418036
Hypoglycaemia 95.75 10.50 84 200101 59770 42361380
Escherichia infection 93.09 10.50 181 200004 11215 42409935
Decreased appetite 92.66 10.50 530 199655 192607 42228543
Confusional state 92.12 10.50 439 199746 167158 42253992
Suicidal ideation 92.10 10.50 56 200129 48105 42373045
Intentional product misuse 91.83 10.50 93 200092 61807 42359343
Feeling abnormal 91.39 10.50 116 200069 69670 42351480
Fungal infection 89.91 10.50 249 199936 19473 42401677
Cytomegalovirus enteritis 89.30 10.50 49 200136 612 42420538
Polyomavirus viraemia 88.68 10.50 76 200109 2036 42419114
Focal segmental glomerulosclerosis 87.79 10.50 82 200103 2466 42418684
Drug resistance 87.76 10.50 356 199829 33892 42387258
COVID-19 86.69 10.50 879 199306 115069 42306081
Somnolence 85.74 10.50 356 199829 140749 42280401
Herpes simplex 84.43 10.50 133 200052 6962 42414188
Hyperglycaemia 83.47 10.50 431 199754 45428 42375722
Transplant dysfunction 82.86 10.50 90 200095 3253 42417897
Myopathy 82.81 10.50 193 199992 13568 42407582
Dyspnoea 82.79 10.50 1523 198662 441098 41980052
Systemic mycosis 82.59 10.50 77 200108 2310 42418840
Corynebacterium infection 81.13 10.50 51 200134 832 42420318
Progressive multifocal leukoencephalopathy 80.90 10.50 172 200013 11364 42409786
Penicillium infection 79.42 10.50 36 200149 288 42420862
Pulmonary mucormycosis 79.37 10.50 61 200124 1394 42419756
Nightmare 78.13 10.50 12 200173 25000 42396150
Pneumonia cryptococcal 77.44 10.50 61 200124 1447 42419703
Accidental overdose 77.11 10.50 19 200166 28311 42392839
COVID-19 pneumonia 76.89 10.50 250 199935 21363 42399787
Systemic candida 76.58 10.50 109 200076 5210 42415940
Nephropathy toxic 76.17 10.50 212 199973 16626 42404524
Pemphigus 75.83 10.50 68 200117 1938 42419212
Cardiac disorder 75.49 10.50 71 200114 48861 42372289
Dry skin 74.73 10.50 70 200115 48268 42372882
Enterobacter infection 74.68 10.50 81 200104 2923 42418227
Malignant neoplasm progression 74.56 10.50 260 199925 108140 42313010
Full blood count abnormal 73.98 10.50 24 200161 29852 42391298
Drug interaction 73.90 10.50 850 199335 266149 42155001
Central nervous system fungal infection 73.67 10.50 38 200147 415 42420735
Lymphopenia 73.65 10.50 246 199939 21317 42399833
Orthostatic hypotension 73.19 10.50 26 200159 30544 42390606
Transient ischaemic attack 72.17 10.50 34 200151 33705 42387445
Back pain 70.71 10.50 384 199801 141392 42279758
International normalised ratio increased 69.60 10.50 74 200111 48094 42373056
Liver transplant rejection 68.21 10.50 71 200114 2442 42418708
Oedema peripheral 68.17 10.50 368 199817 135708 42285442
Leukopenia 67.50 10.50 590 199595 74156 42346994
Pain 67.14 10.50 781 199404 244067 42177083
Peripheral swelling 66.55 10.50 210 199975 90060 42331090
Prostate cancer 66.29 10.50 67 200118 44576 42376574
Pneumonia klebsiella 65.86 10.50 90 200095 4139 42417011
Myalgia 65.70 10.50 231 199954 95849 42325301
Stenotrophomonas infection 65.67 10.50 84 200101 3620 42417530
Thrombosis 65.35 10.50 140 200045 68371 42352779
Staphylococcal sepsis 65.34 10.50 157 200028 11257 42409893
Human herpesvirus 8 infection 65.17 10.50 55 200130 1442 42419708
Plasma cell myeloma 64.48 10.50 77 200108 47501 42373649
Pneumocystis jirovecii infection 64.01 10.50 73 200112 2787 42418363
Pneumonia fungal 63.71 10.50 136 200049 9010 42412140
Pyrexia 63.10 10.50 2352 197833 391690 42029460
Renal transplant failure 62.87 10.50 54 200131 1451 42419699
Anaphylactic shock 62.28 10.50 247 199938 23270 42397880
Acinetobacter infection 62.07 10.50 54 200131 1477 42419673
Loss of personal independence in daily activities 61.96 10.50 86 200099 49730 42371420
Sedation 61.75 10.50 33 200152 30442 42390708
Stress 61.59 10.50 70 200115 44142 42377008
Blood pressure diastolic increased 61.42 10.50 109 200076 6296 42414854
Abdominal discomfort 61.33 10.50 167 200018 75088 42346062
Muscle spasms 60.77 10.50 204 199981 85840 42335310
Disseminated cryptococcosis 60.72 10.50 59 200126 1866 42419284
Gastroenteritis norovirus 60.43 10.50 56 200129 1667 42419483
Osteonecrosis 59.61 10.50 187 199998 15678 42405472
Balance disorder 59.51 10.50 82 200103 47563 42373587
Rhabdomyolysis 59.28 10.50 179 200006 77840 42343310
Epstein-Barr virus associated lymphoproliferative disorder 59.21 10.50 65 200120 2378 42418772
Epstein-Barr viraemia 59.15 10.50 63 200122 2226 42418924
Pneumonia bacterial 58.99 10.50 185 200000 15507 42405643
Accidental exposure to product 58.87 10.50 12 200173 20381 42400769
Rhinocerebral mucormycosis 58.79 10.50 38 200147 652 42420498
Oliguria 58.66 10.50 133 200052 9180 42411970
Bacteraemia 58.46 10.50 253 199932 24787 42396363
Renal tubular atrophy 58.35 10.50 51 200134 1404 42419746
Lethargy 58.26 10.50 81 200104 46809 42374341
Neuropathy peripheral 58.16 10.50 263 199922 101590 42319560
Adverse drug reaction 58.11 10.50 54 200131 37380 42383770
Sleep disorder 57.86 10.50 85 200100 48010 42373140
Varicella zoster virus infection 57.56 10.50 66 200119 2535 42418615
Mycobacterium chelonae infection 56.96 10.50 46 200139 1132 42420018
Disseminated varicella zoster virus infection 56.86 10.50 39 200146 742 42420408
Cytomegalovirus oesophagitis 56.81 10.50 35 200150 550 42420600
Erectile dysfunction 56.62 10.50 23 200162 24890 42396260
Renal tubular necrosis 56.25 10.50 202 199983 18152 42402998
Central nervous system viral infection 55.36 10.50 23 200162 145 42421005
Skin striae 55.31 10.50 38 200147 725 42420425
Intentional product use issue 55.30 10.50 548 199637 71285 42349865
Subcutaneous emphysema 55.07 10.50 53 200132 1656 42419494
JC virus infection 54.64 10.50 69 200116 2935 42418215
Pain in extremity 54.45 10.50 449 199736 150155 42270995
Transplant failure 54.04 10.50 80 200105 3964 42417186
Immunosuppressant drug level decreased 53.99 10.50 54 200131 1770 42419380
Throat irritation 53.99 10.50 159 200026 12877 42408273
Dry mouth 53.55 10.50 65 200120 39814 42381336
Kidney fibrosis 53.49 10.50 65 200120 2657 42418493
Granulomatosis with polyangiitis 53.31 10.50 49 200136 1443 42419707
Extrapyramidal disorder 53.30 10.50 7 200178 16405 42404745
Herpes simplex pneumonia 52.73 10.50 26 200159 256 42420894
Fungaemia 52.29 10.50 69 200116 3067 42418083
New onset diabetes after transplantation 52.21 10.50 24 200161 199 42420951
Adverse event 51.84 10.50 23 200162 23617 42397533
Psoriasis 51.82 10.50 93 200092 48511 42372639
Ear pruritus 51.77 10.50 36 200149 701 42420449
Malaise 51.64 10.50 694 199491 211462 42209688
Aplastic anaemia 51.24 10.50 151 200034 12233 42408917
Miosis 51.02 10.50 3 200182 13443 42407707
Cytomegalovirus enterocolitis 50.55 10.50 46 200139 1337 42419813
Chest pain 50.43 10.50 416 199769 139114 42282036
Product prescribing error 50.42 10.50 30 200155 26082 42395068
Staphylococcal infection 50.33 10.50 326 199859 37317 42383833
Blood immunoglobulin G decreased 50 10.50 58 200127 2256 42418894
Pneumoretroperitoneum 49.81 10.50 21 200164 138 42421012
Anxiety 49.73 10.50 339 199846 118221 42302929
Renal tubular injury 49.61 10.50 51 200134 1728 42419422
Graft versus host disease in liver 49.39 10.50 49 200136 1590 42419560
Cytomegalovirus chorioretinitis 48.84 10.50 82 200103 4529 42416621
Malacoplakia 48.79 10.50 38 200147 886 42420264
Mycobacterium abscessus infection 48.47 10.50 35 200150 725 42420425
Red blood cells urine positive 48.35 10.50 52 200133 1858 42419292
Full blood count decreased 48.35 10.50 18 200167 20542 42400608
Dyspnoea exertional 48.22 10.50 102 200083 50046 42371104
Adenoviral hepatitis 48.16 10.50 31 200154 528 42420622
Intentional self-injury 48.16 10.50 7 200178 15195 42405955
Anaemia 47.79 10.50 979 199206 279299 42141851
Lymphocyte percentage decreased 47.77 10.50 56 200129 2203 42418947
Psoriatic arthropathy 47.77 10.50 29 200156 24938 42396212
Hyponatraemia 47.75 10.50 280 199905 101182 42319968
Intensive care unit acquired weakness 47.67 10.50 43 200142 1235 42419915
Aggression 47.53 10.50 84 200101 44079 42377071
Enterocolitis viral 47.50 10.50 29 200156 448 42420702
Necrotising retinitis 47.24 10.50 39 200146 991 42420159
Pneumonia acinetobacter 47.04 10.50 23 200162 222 42420928
Neuroleptic malignant syndrome 46.92 10.50 21 200164 21451 42399699
Serum sickness 46.79 10.50 55 200130 2170 42418980
Pulmonary embolism 46.76 10.50 349 199836 119263 42301887
Abdominal abscess 46.70 10.50 85 200100 5008 42416142
Cutaneous mucormycosis 46.47 10.50 32 200153 613 42420537
Hypoalbuminaemia 46.31 10.50 170 200015 15440 42405710
Thyrotoxic periodic paralysis 46.22 10.50 21 200164 169 42420981
Amoebic colitis 46.12 10.50 18 200167 94 42421056
Device malfunction 46.03 10.50 3 200182 12324 42408826
Cerebral fungal infection 45.76 10.50 26 200159 349 42420801
Dysgeusia 45.62 10.50 56 200129 34133 42387017
Neutrophil percentage increased 45.42 10.50 51 200134 1914 42419236
Headache 45.41 10.50 821 199364 238548 42182602
Herpes simplex hepatitis 45.10 10.50 20 200165 151 42420999
Pharyngeal paraesthesia 45.03 10.50 36 200149 873 42420277
Injection site swelling 45.01 10.50 12 200173 16961 42404189
Diffuse alveolar damage 44.73 10.50 58 200127 2534 42418616
Viral haemorrhagic cystitis 44.36 10.50 49 200136 1805 42419345
Insomnia 44.36 10.50 349 199836 117904 42303246
Pneumonia pseudomonal 43.84 10.50 81 200104 4828 42416322
Depressed mood 43.58 10.50 28 200157 23356 42397794
Chorioretinopathy 42.90 10.50 44 200141 1487 42419663
Fusarium infection 42.69 10.50 45 200140 1571 42419579
Medication error 42.47 10.50 56 200129 33098 42388052
Blood pressure diastolic decreased 42.44 10.50 126 200059 10249 42410901
Therapy interrupted 42.35 10.50 26 200159 22224 42398926
Ureaplasma infection 42.20 10.50 30 200155 606 42420544
Pneumothorax 41.95 10.50 220 199965 23323 42397827
Contusion 41.54 10.50 84 200101 41901 42379249
Cryptococcal meningoencephalitis 41.18 10.50 20 200165 190 42420960
Large intestine perforation 41.11 10.50 118 200067 9418 42411732
Human ehrlichiosis 40.90 10.50 27 200158 481 42420669
Urine analysis abnormal 40.87 10.50 51 200134 2143 42419007
Immunosuppression 40.80 10.50 109 200076 8344 42412806
Diffuse large B-cell lymphoma 40.77 10.50 117 200068 9337 42411813
Injection site erythema 40.72 10.50 22 200163 20173 42400977
Gait disturbance 40.70 10.50 281 199904 97719 42323431
Cytokine release syndrome 40.46 10.50 352 199833 44175 42376975
Eczema 40.26 10.50 61 200124 34025 42387125
Poisoning 39.73 10.50 10 200175 14689 42406461
Incorrect dose administered 39.20 10.50 123 200062 52851 42368299
Osteomyelitis fungal 39.15 10.50 23 200162 330 42420820
Glomerulonephritis 39.04 10.50 54 200131 2512 42418638
Osteoporosis 39.02 10.50 156 200029 14750 42406400
American trypanosomiasis 38.97 10.50 23 200162 333 42420817
Familial periodic paralysis 38.78 10.50 18 200167 153 42420997
Scedosporium infection 38.71 10.50 42 200143 1516 42419634
Product substitution issue 38.70 10.50 4 200181 11286 42409864
Memory impairment 38.30 10.50 115 200070 50107 42371043
Product quality issue 38.27 10.50 18 200167 17864 42403286
Growth retardation 38.24 10.50 52 200133 2380 42418770
Neck pain 38.14 10.50 51 200134 29963 42391187
Opportunistic infection 38.05 10.50 47 200138 1954 42419196
Respiratory symptom 37.90 10.50 4 200181 11102 42410048
Hypertension 37.88 10.50 1041 199144 166163 42254987
Quadriplegia 37.83 10.50 49 200136 2138 42419012
Heart transplant rejection 37.50 10.50 41 200144 1493 42419657
Apoptosis 37.12 10.50 27 200158 566 42420584
Phaeohyphomycosis 36.80 10.50 36 200149 1148 42420002
Sepsis 36.80 10.50 1210 198975 198124 42223026
Atrial fibrillation 36.76 10.50 449 199736 139144 42282006
Treatment noncompliance 36.74 10.50 76 200109 37596 42383554
Disseminated blastomycosis 36.60 10.50 23 200162 375 42420775
Chronic obstructive pulmonary disease 36.60 10.50 162 200023 62952 42358198
Cardiac infection 36.57 10.50 20 200165 248 42420902
Acute hepatic failure 36.46 10.50 168 200017 16905 42404245
Electrocardiogram QT prolonged 36.41 10.50 110 200075 47835 42373315
General physical health deterioration 36.32 10.50 496 199689 150750 42270400
Fungal skin infection 36.17 10.50 60 200125 3281 42417869
Hypophagia 36.12 10.50 44 200141 26912 42394238
Viraemia 35.98 10.50 43 200142 1727 42419423
Enterococcal bacteraemia 35.98 10.50 53 200132 2614 42418536
Herpes zoster 35.66 10.50 308 199877 38569 42382581
Renal impairment 35.62 10.50 721 199464 109507 42311643
Dyskinesia 35.57 10.50 40 200145 25350 42395800
Respiratory tract infection fungal 35.47 10.50 30 200155 789 42420361
Disseminated strongyloidiasis 35.29 10.50 25 200160 502 42420648
Palmar-plantar erythrodysaesthesia syndrome 35.25 10.50 27 200158 20555 42400595
Blood creatine phosphokinase increased 35.23 10.50 113 200072 48225 42372925
Type I hypersensitivity 35.11 10.50 47 200138 2119 42419031
Device issue 34.98 10.50 10 200175 13499 42407651
Empyema 34.88 10.50 67 200118 4113 42417037
Pulmonary alveolar haemorrhage 34.81 10.50 150 200035 14666 42406484
Drug intolerance 34.69 10.50 228 199957 80196 42340954
Hypocomplementaemia 34.60 10.50 13 200172 60 42421090
Dural arteriovenous fistula 34.60 10.50 13 200172 60 42421090
Necrosis ischaemic 34.47 10.50 22 200163 369 42420781
Neurological decompensation 34.44 10.50 63 200122 3726 42417424
Device leakage 34.35 10.50 4 200181 10281 42410869
Hallucination 34.32 10.50 146 200039 57361 42363789
Haemolytic anaemia 34.25 10.50 130 200055 11997 42409153
Candida sepsis 34.25 10.50 38 200147 1407 42419743
Tremor 34.09 10.50 291 199894 96638 42324512
Injection site haemorrhage 33.68 10.50 7 200178 11729 42409421
Bronchopleural fistula 33.59 10.50 27 200158 660 42420490
Crystal urine present 33.56 10.50 23 200162 437 42420713
Drug withdrawal syndrome 33.54 10.50 31 200154 21518 42399632
Autoimmune haemolytic anaemia 33.53 10.50 79 200106 5592 42415558
Ureteric stenosis 33.27 10.50 35 200150 1219 42419931
Cardiac failure 33.18 10.50 331 199854 106525 42314625
Intestinal ischaemia 32.85 10.50 108 200077 9280 42411870
Injection site bruising 32.82 10.50 7 200178 11518 42409632
Coronary artery dilatation 32.69 10.50 11 200174 34 42421116
Arteriosclerosis coronary artery 32.63 10.50 24 200161 18653 42402497
Respiratory arrest 32.49 10.50 52 200133 28372 42392778
Laboratory test abnormal 32.41 10.50 36 200149 22942 42398208
Abdominal pain upper 32.29 10.50 241 199944 82368 42338782
Idiopathic pneumonia syndrome 32.21 10.50 23 200162 468 42420682
Treatment failure 32.20 10.50 442 199743 62182 42358968
Incision site pain 31.93 10.50 42 200143 1861 42419289
Osmotic demyelination syndrome 31.89 10.50 31 200154 981 42420169
Glomerulosclerosis 31.80 10.50 29 200156 845 42420305
Pseudomonal sepsis 31.72 10.50 65 200120 4184 42416966
Meningitis cryptococcal 31.65 10.50 56 200129 3227 42417923
Haemolytic uraemic syndrome 31.64 10.50 48 200137 2431 42418719
Pseudomonal bacteraemia 31.44 10.50 47 200138 2349 42418801
Substance-induced psychotic disorder 31.43 10.50 52 200133 2837 42418313
Cytomegalovirus gastrointestinal infection 31.36 10.50 20 200165 335 42420815
Central nervous system infection 31.24 10.50 29 200156 865 42420285
Inferior vena cava stenosis 31.02 10.50 13 200172 84 42421066
Urine abnormality 30.94 10.50 45 200140 2194 42418956
Intra-abdominal haemorrhage 30.92 10.50 52 200133 2876 42418274
Hyperkalaemia 30.84 10.50 236 199949 80222 42340928
Rectal haemorrhage 30.81 10.50 124 200061 49482 42371668
Sideroblastic anaemia 30.75 10.50 20 200165 347 42420803
Encephalopathy 30.68 10.50 313 199872 41020 42380130
Obliterative bronchiolitis 30.54 10.50 36 200149 1425 42419725
Cytomegalovirus hepatitis 30.52 10.50 23 200162 510 42420640
Needle issue 30.15 10.50 3 200182 8724 42412426
Trichosporon infection 29.69 10.50 29 200156 923 42420227
Abdominal distension 29.62 10.50 206 199979 71529 42349621
Venoocclusive liver disease 29.56 10.50 111 200074 10191 42410959
Oesophageal carcinoma 29.50 10.50 5 200180 9691 42411459
Haemodynamic instability 29.40 10.50 127 200058 12430 42408720
Splenic embolism 29.32 10.50 18 200167 281 42420869
Product storage error 29.30 10.50 8 200177 11132 42410018
Respiratory distress 29.30 10.50 313 199872 41507 42379643
Contraindicated product administered 29.11 10.50 46 200139 25226 42395924
Drug dependence 28.96 10.50 58 200127 29036 42392114
Swelling 28.81 10.50 146 200039 54739 42366411
Heart rate increased 28.67 10.50 379 199806 52876 42368274
Monkeypox 28.56 10.50 20 200165 394 42420756
Salivary hypersecretion 28.52 10.50 8 200177 10935 42410215
Disturbance in attention 28.49 10.50 61 200124 29805 42391345
Palpitations 28.48 10.50 132 200053 50665 42370485
Epstein-Barr virus infection reactivation 28.20 10.50 47 200138 2580 42418570
Perinephric abscess 28.10 10.50 11 200174 58 42421092
Lung abscess 28.09 10.50 53 200132 3210 42417940
Pulmonary haemorrhage 28.03 10.50 117 200068 11280 42409870
Unevaluable event 27.99 10.50 76 200109 34212 42386938
Adenoviral haemorrhagic cystitis 27.96 10.50 22 200163 521 42420629
Toxic epidermal necrolysis 27.80 10.50 218 199967 26532 42394618
Pathogen resistance 27.73 10.50 117 200068 11333 42409817
Parvovirus infection 27.66 10.50 21 200164 471 42420679
Unresponsive to stimuli 27.64 10.50 67 200118 31336 42389814
Ventricular fibrillation 27.53 10.50 63 200122 30060 42391090
Cholelithiasis 27.36 10.50 42 200143 23304 42397846
Atypical mycobacterial pneumonia 27.33 10.50 16 200169 228 42420922
Incorrect route of product administration 27.28 10.50 45 200140 24260 42396890
Appendicitis 27.25 10.50 34 200151 20579 42400571
Peritonitis 27.16 10.50 165 200020 18468 42402682
Skin necrosis 27.09 10.50 78 200107 6236 42414914
Polychondritis 27.06 10.50 19 200166 376 42420774
Liver abscess 26.99 10.50 67 200118 4903 42416247
Syringe issue 26.96 10.50 4 200181 8552 42412598
Blastomycosis 26.88 10.50 24 200161 680 42420470
Hospice care 26.78 10.50 4 200181 8509 42412641
Subdural haematoma 26.76 10.50 42 200143 23096 42398054
Obstructive airways disorder 26.72 10.50 47 200138 24712 42396438
Asthma 26.69 10.50 177 200008 62137 42359013
Viral sepsis 26.54 10.50 13 200172 126 42421024
Human herpesvirus 6 infection reactivation 26.40 10.50 20 200165 447 42420703
Steroid withdrawal syndrome 26.29 10.50 17 200168 292 42420858
Blood beta-D-glucan increased 26.27 10.50 21 200164 509 42420641
Porphyria acute 26.17 10.50 19 200166 397 42420753
Staphylococcal mediastinitis 26.14 10.50 10 200175 49 42421101
Bordetella infection 26.07 10.50 14 200171 167 42420983
Specific gravity urine increased 26.07 10.50 14 200171 167 42420983
Tinnitus 26.06 10.50 61 200124 28877 42392273
Histoplasmosis disseminated 26.00 10.50 40 200145 2051 42419099
Ecthyma 25.96 10.50 23 200162 645 42420505
Neuromyelitis optica spectrum disorder 25.94 10.50 16 200169 252 42420898
Organising pneumonia 25.78 10.50 86 200099 7446 42413704
Abnormal dreams 25.76 10.50 4 200181 8267 42412883
Cerebral venous thrombosis 25.76 10.50 28 200157 1013 42420137
Periumbilical abscess 25.75 10.50 11 200174 75 42421075
Encephalitis fungal 25.73 10.50 15 200170 212 42420938
Therapy cessation 25.73 10.50 35 200150 20415 42400735
Skin exfoliation 25.72 10.50 104 200081 41449 42379701
Hepatic failure 25.69 10.50 283 199902 37817 42383333
C-reactive protein abnormal 25.62 10.50 6 200179 9255 42411895
Angiosarcoma 25.60 10.50 18 200167 357 42420793
Gastric disorder 25.52 10.50 12 200173 11910 42409240
Monocyte percentage increased 25.45 10.50 28 200157 1027 42420123
Serotonin syndrome 25.32 10.50 52 200133 25793 42395357
Gastritis fungal 25.28 10.50 13 200172 141 42421009
Abdominal pain 25.26 10.50 691 199494 189780 42231370
Immune thrombocytopenia 25.17 10.50 112 200073 11104 42410046
Tularaemia 25.16 10.50 14 200171 180 42420970
Orchitis 25.14 10.50 41 200144 2210 42418940
Respiratory depression 25.07 10.50 31 200154 18837 42402313
Encephalitis cytomegalovirus 25.02 10.50 30 200155 1209 42419941
Splenic infection viral 24.97 10.50 9 200176 36 42421114
Cerebral aspergillosis 24.97 10.50 36 200149 1741 42419409
Renal graft infection 24.96 10.50 18 200167 372 42420778
Enterococcus test positive 24.95 10.50 35 200150 1650 42419500
Akathisia 24.82 10.50 9 200176 10442 42410708
Campylobacter gastroenteritis 24.80 10.50 28 200157 1057 42420093
Musculoskeletal stiffness 24.78 10.50 164 200021 57601 42363549
Therapy partial responder 24.71 10.50 170 200015 19851 42401299
Lip ulceration 24.70 10.50 27 200158 983 42420167
Complications of transplant surgery 24.63 10.50 20 200165 496 42420654
Pyelonephritis acute 24.56 10.50 43 200142 2457 42418693
Withdrawal syndrome 24.52 10.50 20 200165 14755 42406395
Blood immunoglobulin M decreased 24.47 10.50 25 200160 841 42420309
B-lymphocyte count decreased 24.39 10.50 25 200160 844 42420306
Red blood cell schistocytes present 24.36 10.50 17 200168 333 42420817
Graft complication 24.31 10.50 23 200162 703 42420447
Reticulocytosis 24.28 10.50 16 200169 284 42420866
Erythema 24.24 10.50 676 199509 108117 42313033
Epistaxis 24.22 10.50 199 199986 66627 42354523
Alveolar proteinosis 24.21 10.50 23 200162 707 42420443
Aspiration 24.17 10.50 29 200156 17857 42403293
Staphylococcal bacteraemia 24.17 10.50 110 200075 11011 42410139
Symptom masked 24.11 10.50 25 200160 856 42420294
Cytomegalovirus gastritis 24.09 10.50 16 200169 288 42420862
Hypothyroidism 24.08 10.50 74 200111 32010 42389140
Respiratory disorder 24.07 10.50 182 200003 21903 42399247
Meningitis fungal 24.06 10.50 14 200171 197 42420953
Dyspepsia 24.05 10.50 106 200079 41246 42379904
Injection site reaction 24.02 10.50 23 200162 15698 42405452
T-cell type acute leukaemia 24.00 10.50 14 200171 198 42420952
Gastrointestinal candidiasis 24.00 10.50 13 200172 158 42420992
Infective pulmonary exacerbation of cystic fibrosis 23.85 10.50 4 200181 7814 42413336
Parkinsonism 23.83 10.50 10 200175 10613 42410537
Human polyomavirus infection 23.81 10.50 30 200155 1273 42419877
Aplasia pure red cell 23.80 10.50 81 200104 7085 42414065
Shock 23.79 10.50 225 199960 28896 42392254
Underdose 23.63 10.50 26 200159 16640 42404510
Sudden death 23.51 10.50 26 200159 16603 42404547
Epstein-Barr virus associated lymphoma 23.50 10.50 27 200158 1039 42420111
Urinary retention 23.48 10.50 110 200075 42104 42379046
Klebsiella sepsis 23.41 10.50 44 200141 2657 42418493
Graft loss 23.32 10.50 25 200160 890 42420260
Protein urine present 23.30 10.50 70 200115 5731 42415419
Proteinuria 23.17 10.50 186 199999 22797 42398353
Muscle rigidity 23.08 10.50 14 200171 12045 42409105
Disseminated toxoplasmosis 23.07 10.50 15 200170 260 42420890
Acute myocardial infarction 23.05 10.50 169 200016 57996 42363154
Anti-neutrophil cytoplasmic antibody positive vasculitis 23.02 10.50 32 200153 1496 42419654
Hemianopia 22.94 10.50 25 200160 907 42420243
Injection site mass 22.85 10.50 6 200179 8569 42412581
Respiratory tract inflammation 22.85 10.50 18 200167 427 42420723
Spinal cord abscess 22.81 10.50 18 200167 428 42420722
Blood glucose decreased 22.68 10.50 20 200165 14199 42406951
Pericarditis fungal 22.67 10.50 14 200171 221 42420929
Flatulence 22.66 10.50 53 200132 25099 42396051
Nephritis 22.64 10.50 53 200132 3736 42417414
Mycotic endophthalmitis 22.61 10.50 14 200171 222 42420928
Gingival pain 22.53 10.50 6 200179 8488 42412662
Herpes zoster meningoencephalitis 22.52 10.50 19 200166 498 42420652
Renal cyst infection 22.42 10.50 11 200174 107 42421043
Viral cardiomyopathy 22.40 10.50 8 200177 31 42421119
Gastrooesophageal reflux disease 22.38 10.50 122 200063 44901 42376249
Tardive dyskinesia 22.37 10.50 3 200182 6921 42414229
Hyperphosphataemia 22.34 10.50 17 200168 12987 42408163
Hepatic artery aneurysm 22.31 10.50 9 200176 52 42421098
Hepatitis E 22.29 10.50 47 200138 3087 42418063
Fluid retention 22.29 10.50 75 200110 31544 42389606
Vision blurred 22.27 10.50 154 200031 53545 42367605
Chills 22.23 10.50 589 199596 93477 42327673
Lung transplant rejection 22.22 10.50 26 200159 1021 42420129
Smooth muscle cell neoplasm 22.16 10.50 15 200170 279 42420871
Lupus nephritis 22.08 10.50 19 200166 512 42420638
Serratia sepsis 22.00 10.50 12 200173 148 42421002
Human herpesvirus 6 encephalitis 21.98 10.50 20 200165 581 42420569
Plasmodium falciparum infection 21.95 10.50 10 200175 81 42421069
Body temperature decreased 21.88 10.50 129 200056 14284 42406866
Angina pectoris 21.86 10.50 80 200105 32816 42388334
Knee arthroplasty 21.83 10.50 7 200178 8774 42412376
Middle insomnia 21.81 10.50 5 200180 7828 42413322
Terminal ileitis 21.73 10.50 20 200165 590 42420560
Bradycardia 21.72 10.50 277 199908 85207 42335943
Hepatic cirrhosis 21.63 10.50 37 200148 19665 42401485
Hypersomnia 21.63 10.50 22 200163 14596 42406554
Herpes simplex viraemia 21.50 10.50 11 200174 118 42421032
Ageusia 21.48 10.50 14 200171 11591 42409559
Arteriosclerosis 21.43 10.50 32 200153 17957 42403193
B-cell lymphoma 21.38 10.50 61 200124 4852 42416298
Labelled drug-drug interaction medication error 21.34 10.50 25 200160 15557 42405593
Fungal sepsis 21.30 10.50 26 200159 1068 42420082
Low birth weight baby 21.28 10.50 98 200087 9857 42411293
Lymphocele 21.24 10.50 31 200154 1516 42419634
Parosmia 21.24 10.50 5 200180 7686 42413464
Migraine 20.99 10.50 56 200129 25358 42395792
Lung neoplasm malignant 20.98 10.50 36 200149 19111 42402039
Blood sodium decreased 20.97 10.50 33 200152 18129 42403021
Fungal peritonitis 20.95 10.50 24 200161 921 42420229
Injection site pruritus 20.86 10.50 9 200176 9396 42411754
Prescribed overdose 20.84 10.50 18 200167 12909 42408241
Fibrin D dimer increased 20.83 10.50 61 200124 4924 42416226
Encephalitis brain stem 20.80 10.50 12 200173 166 42420984
Engraftment syndrome 20.77 10.50 29 200156 1361 42419789
Hepatic artery thrombosis 20.70 10.50 14 200171 260 42420890
Device related sepsis 20.69 10.50 52 200133 3835 42417315
Sarcopenia 20.66 10.50 23 200162 855 42420295
Bladder cancer 20.62 10.50 30 200155 17017 42404133
Superinfection bacterial 20.55 10.50 29 200156 1375 42419775
Breath sounds abnormal 20.53 10.50 16 200169 12077 42409073
Impaired work ability 20.53 10.50 16 200169 12075 42409075
Seronegative arthritis 20.51 10.50 27 200158 1197 42419953
Nephrolithiasis 20.47 10.50 96 200089 36734 42384416
Brain abscess 20.43 10.50 55 200130 4229 42416921
Infective aneurysm 20.34 10.50 25 200160 1034 42420116
Herpes virus infection 20.29 10.50 50 200135 3642 42417508
Chromophobe renal cell carcinoma 20.29 10.50 9 200176 68 42421082
Retinal detachment 20.15 10.50 72 200113 6453 42414697
Febrile bone marrow aplasia 20.15 10.50 98 200087 10083 42411067
Serum ferritin increased 20.07 10.50 77 200108 7142 42414008
Disseminated aspergillosis 19.99 10.50 32 200153 1698 42419452
Dementia 19.94 10.50 29 200156 16451 42404699
Cardiovascular disorder 19.90 10.50 20 200165 13345 42407805
Systemic inflammatory response syndrome 19.87 10.50 78 200107 7312 42413838
Rash 19.84 10.50 1081 199104 275873 42145277
Tracheobronchitis viral 19.83 10.50 7 200178 26 42421124
Epstein-Barr virus test positive 19.79 10.50 20 200165 664 42420486
Duodenal perforation 19.78 10.50 31 200154 1615 42419535
Glomerulonephritis rapidly progressive 19.78 10.50 23 200162 897 42420253
Swollen tongue 19.73 10.50 44 200141 21187 42399963
Wound evisceration 19.73 10.50 10 200175 105 42421045
Spinal cord injury cervical 19.73 10.50 14 200171 282 42420868
Leukocytosis 19.72 10.50 220 199965 29488 42391662
Drug hypersensitivity 19.72 10.50 338 199847 99051 42322099
Dysarthria 19.71 10.50 108 200077 39699 42381451
Pneumoperitoneum 19.70 10.50 38 200147 2340 42418810
Pneumocephalus 19.68 10.50 12 200173 185 42420965
Latent autoimmune diabetes in adults 19.66 10.50 11 200174 143 42421007
Small intestinal perforation 19.65 10.50 43 200142 2898 42418252
Glycosylated haemoglobin increased 19.64 10.50 19 200166 12905 42408245
Paraplegia 19.57 10.50 46 200139 3251 42417899
Inflammatory marker increased 19.56 10.50 73 200112 6683 42414467
Blood phosphorus increased 19.52 10.50 18 200167 12507 42408643
Secondary immunodeficiency 19.41 10.50 22 200163 834 42420316
Nocturia 19.36 10.50 17 200168 12095 42409055
Hepatic function abnormal 19.28 10.50 345 199840 51222 42369928
Blood potassium increased 19.28 10.50 36 200149 18500 42402650
Exposure during pregnancy 19.25 10.50 8 200177 8540 42412610
Candida pneumonia 19.20 10.50 21 200164 765 42420385
Acinetobacter sepsis 19.17 10.50 10 200175 112 42421038
Scopulariopsis infection 19.14 10.50 11 200174 151 42420999
Escherichia sepsis 19.12 10.50 65 200120 5682 42415468
Limbic encephalitis 19.07 10.50 16 200169 416 42420734
Torulopsis infection 19.04 10.50 6 200179 14 42421136
Hepatic cancer 18.99 10.50 8 200177 8472 42412678
Cystitis escherichia 18.97 10.50 12 200173 198 42420952
Anaphylactic reaction 18.94 10.50 294 199891 42449 42378701
Osteoporotic fracture 18.92 10.50 29 200156 1482 42419668
Immune reconstitution inflammatory syndrome 18.91 10.50 96 200089 10047 42411103
Alcohol poisoning 18.90 10.50 6 200179 7568 42413582
Post procedural bile leak 18.86 10.50 14 200171 303 42420847
Head injury 18.84 10.50 43 200142 20539 42400611
Delusion 18.75 10.50 25 200160 14709 42406441
Cystitis viral 18.69 10.50 26 200159 1216 42419934
Microsporidia infection 18.67 10.50 25 200160 1127 42420023
Micturition urgency 18.66 10.50 17 200168 11881 42409269
Enterococcal sepsis 18.60 10.50 34 200151 2010 42419140
Pyelonephritis 18.50 10.50 80 200105 7834 42413316
Flushing 18.48 10.50 260 199925 36768 42384382
Mobility decreased 18.48 10.50 94 200091 35212 42385938
Status epilepticus 18.48 10.50 131 200054 15447 42405703
Intestinal ulcer 18.43 10.50 24 200161 1053 42420097
Tracheobronchitis 18.42 10.50 27 200158 1326 42419824
Venoocclusive disease 18.41 10.50 50 200135 3865 42417285
Red cell distribution width increased 18.32 10.50 73 200112 6891 42414259
Irritability 18.30 10.50 69 200116 28059 42393091
Donor specific antibody present 18.30 10.50 11 200174 165 42420985
Muscle twitching 18.27 10.50 17 200168 11763 42409387
Acute respiratory failure 18.27 10.50 270 199915 38588 42382562
Serratia infection 18.26 10.50 26 200159 1243 42419907
Gastrointestinal fungal infection 18.23 10.50 13 200172 264 42420886
Bronchopneumopathy 18.22 10.50 18 200167 581 42420569
Vitritis infective 18.21 10.50 6 200179 17 42421133
Road traffic accident 18.21 10.50 39 200146 19054 42402096
Amoebiasis 18.13 10.50 9 200176 90 42421060
Bacterial pyelonephritis 18.10 10.50 14 200171 323 42420827
Bilirubin urine present 18.07 10.50 11 200174 169 42420981
Priapism 18.02 10.50 4 200181 6403 42414747
Encephalitis 18.01 10.50 88 200097 9070 42412080
Marginal zone lymphoma 18.01 10.50 10 200175 128 42421022
Throat tightness 18.00 10.50 91 200094 9508 42411642
Dysphagia 17.97 10.50 237 199948 72482 42348668
Bifidobacterium infection 17.96 10.50 9 200176 92 42421058
Peritoneal candidiasis 17.96 10.50 6 200179 18 42421132
Autoimmune thyroiditis 17.92 10.50 29 200156 1553 42419597
Gastrointestinal ulcer 17.91 10.50 32 200153 1858 42419292
Enterovirus infection 17.88 10.50 26 200159 1267 42419883
Myoclonus 17.87 10.50 33 200152 17032 42404118
Shock haemorrhagic 17.78 10.50 134 200051 16108 42405042
Faeces discoloured 17.73 10.50 33 200152 16981 42404169
Mental impairment 17.70 10.50 19 200166 12298 42408852
Lymphocytosis 17.68 10.50 42 200143 2989 42418161
Seizure 17.67 10.50 431 199754 120130 42301020
Cryptitis 17.65 10.50 13 200172 278 42420872
Epididymitis 17.65 10.50 42 200143 2992 42418158
Cutaneous malacoplakia 17.61 10.50 10 200175 134 42421016
Sexual dysfunction 17.57 10.50 5 200180 6770 42414380
Lipoma 17.51 10.50 34 200151 2104 42419046
Myelocyte present 17.46 10.50 4 200181 0 42421150
Plasma cell myeloma recurrent 17.45 10.50 3 200182 5754 42415396
Sodium retention 17.39 10.50 9 200176 99 42421051
Urinary tract infection bacterial 17.39 10.50 36 200149 2334 42418816
Brain herniation 17.34 10.50 56 200129 4767 42416383
Activated partial thromboplastin time prolonged 17.33 10.50 30 200155 15873 42405277
Troponin increased 17.31 10.50 40 200145 19022 42402128
Neuritis 17.26 10.50 4 200181 6216 42414934
Arthritis 17.26 10.50 121 200064 41944 42379206
Pulmonary tuberculosis 17.24 10.50 61 200124 5440 42415710
Blindness cortical 17.22 10.50 16 200169 478 42420672
Sleep disorder due to a general medical condition 17.19 10.50 35 200150 17418 42403732
Disseminated coccidioidomycosis 17.16 10.50 9 200176 102 42421048
Cutaneous B-cell lymphoma 17.13 10.50 8 200177 69 42421081
Eye luxation 17.09 10.50 5 200180 8 42421142
Panic attack 17.06 10.50 16 200169 11029 42410121
Cardiomegaly 17.05 10.50 33 200152 16733 42404417
Pancreatitis 17.01 10.50 126 200059 43142 42378008
Intestine transplant rejection 17.00 10.50 7 200178 43 42421107
Restlessness 16.99 10.50 75 200110 29174 42391976
Pneumonia staphylococcal 16.95 10.50 45 200140 3431 42417719
Skin burning sensation 16.87 10.50 7 200178 7480 42413670
Agitation 16.86 10.50 207 199978 64107 42357043
Splenic abscess 16.81 10.50 18 200167 640 42420510
Gonococcal infection 16.73 10.50 7 200178 45 42421105
Complications of transplanted liver 16.70 10.50 13 200172 303 42420847
Acute disseminated encephalomyelitis 16.69 10.50 10 200175 149 42421001
Paranoia 16.66 10.50 25 200160 14001 42407149
Prostatic specific antigen increased 16.62 10.50 34 200151 16891 42404259
Haematemesis 16.62 10.50 79 200106 30120 42391030
Rheumatoid arthritis 16.60 10.50 286 199899 42154 42378996
Microscopic polyangiitis 16.60 10.50 12 200173 249 42420901
Hepatitis B 16.58 10.50 69 200116 6642 42414508
Necrotising soft tissue infection 16.58 10.50 10 200175 151 42420999
Neutropenic sepsis 16.56 10.50 31 200154 15915 42405235
Presyncope 16.54 10.50 52 200133 22335 42398815
Cold type haemolytic anaemia 16.52 10.50 11 200174 199 42420951
Endocarditis 16.51 10.50 79 200106 8073 42413077
Accident 16.50 10.50 5 200180 6498 42414652
Osteonecrosis of jaw 16.48 10.50 41 200144 19008 42402142
Immunoglobulin G4 related disease 16.48 10.50 12 200173 252 42420898
Episcleritis 16.47 10.50 11 200174 200 42420950
Loss of consciousness 16.46 10.50 320 199865 92034 42329116
Antibody test positive 16.46 10.50 19 200166 735 42420415
Atrioventricular block first degree 16.45 10.50 5 200180 6486 42414664
Abdominal compartment syndrome 16.43 10.50 23 200162 1082 42420068
Thrombocytopenia 16.42 10.50 1070 199115 189209 42231941
Graft infection 16.40 10.50 15 200170 439 42420711
Bundle branch block left 16.39 10.50 5 200180 6471 42414679
Tuberculosis 16.39 10.50 92 200093 10007 42411143
Pneumonia escherichia 16.36 10.50 18 200167 660 42420490
Lymphoproliferative disorder 16.32 10.50 43 200142 3264 42417886
Pancreas transplant rejection 16.28 10.50 11 200174 204 42420946
Product administration error 16.25 10.50 39 200146 18304 42402846
Coronary artery aneurysm 16.22 10.50 9 200176 115 42421035
Cutaneous nocardiosis 16.14 10.50 11 200174 207 42420943
Mycobacterium marinum infection 16.13 10.50 16 200169 519 42420631
Fungal abscess central nervous system 16.13 10.50 10 200175 159 42420991
Shock symptom 16.13 10.50 10 200175 159 42420991
Fungal endocarditis 16.12 10.50 15 200170 449 42420701
Intestinal intraepithelial lymphocytes increased 16.10 10.50 11 200174 208 42420942
Ileal ulcer 16.10 10.50 21 200164 923 42420227
Bacterial test 16.08 10.50 10 200175 160 42420990
Faciobrachial dystonic seizure 16.03 10.50 8 200177 81 42421069
Herpes oesophagitis 16.02 10.50 10 200175 161 42420989
Dystonia 15.98 10.50 22 200163 12768 42408382
Joint swelling 15.97 10.50 224 199961 67798 42353352
Lymph gland infection 15.96 10.50 11 200174 211 42420939
Blood calcium increased 15.92 10.50 10 200175 8444 42412706
Mediastinitis 15.91 10.50 22 200163 1023 42420127
Phaeochromocytoma 15.89 10.50 12 200173 267 42420883
Abnormal behaviour 15.87 10.50 67 200118 26384 42394766
Multi-organ disorder 15.83 10.50 25 200160 1311 42419839
Microangiopathic haemolytic anaemia 15.77 10.50 23 200162 1124 42420026
White blood cells urine positive 15.76 10.50 26 200159 1415 42419735
Emotional disorder 15.76 10.50 5 200180 6309 42414841
Optic perineuritis 15.75 10.50 6 200179 29 42421121
Coma 15.74 10.50 168 200017 53386 42367764
Joint injury 15.71 10.50 28 200157 14648 42406502
Arterial spasm 15.70 10.50 8 200177 85 42421065
Endocarditis bacterial 15.62 10.50 24 200161 1229 42419921
Metastases to salivary gland 15.62 10.50 8 200177 86 42421064
Mycobacterial infection 15.59 10.50 37 200148 2631 42418519
Ileocaecal resection 15.58 10.50 14 200171 400 42420750
Tachypnoea 15.58 10.50 163 200022 21499 42399651
Intravascular haemolysis 15.57 10.50 16 200169 542 42420608
Demyelination 15.53 10.50 44 200141 3485 42417665
Demodicidosis 15.52 10.50 11 200174 221 42420929
Anuria 15.49 10.50 100 200085 11432 42409718
Lumbosacral plexus lesion 15.48 10.50 5 200180 13 42421137
Monocytopenia 15.46 10.50 8 200177 88 42421062
Diaphragmatic injury 15.45 10.50 9 200176 127 42421023
Arthralgia 15.45 10.50 797 199388 204441 42216709
Atypical mycobacterial infection 15.42 10.50 25 200160 1341 42419809
Interstitial lung disease 15.41 10.50 480 199705 77982 42343168
Pulmonary air leakage 15.40 10.50 11 200174 224 42420926
Acute hepatitis C 15.39 10.50 9 200176 128 42421022
Necrosis 15.37 10.50 67 200118 6584 42414566
Mycoplasma infection 15.35 10.50 17 200168 628 42420522
Hepatitis A 15.33 10.50 16 200169 552 42420598
Gynaecomastia 15.32 10.50 22 200163 12545 42408605
Electrocardiogram abnormal 15.32 10.50 15 200170 10130 42411020
Hypopnoea 15.29 10.50 9 200176 7873 42413277
Alopecia 15.29 10.50 78 200107 29198 42391952
Disseminated tuberculosis 15.26 10.50 38 200147 2786 42418364
Urobilinogen urine increased 15.24 10.50 13 200172 346 42420804
Blindness 15.23 10.50 140 200045 17838 42403312
Lymphangitis 15.20 10.50 17 200168 635 42420515
Pruritus 15.18 10.50 728 199457 188043 42233107
Haptoglobin decreased 15.16 10.50 18 200167 718 42420432
Passenger lymphocyte syndrome 15.15 10.50 8 200177 92 42421058
Femoral nerve palsy 15.13 10.50 7 200178 59 42421091
Hyperhidrosis 15.12 10.50 317 199868 90195 42330955
Diarrhoea haemorrhagic 15.12 10.50 74 200111 7633 42413517
Skin discolouration 15.10 10.50 49 200136 20841 42400309
Urticaria 15.09 10.50 455 199730 73581 42347569
Arrhythmia 15.09 10.50 119 200066 40198 42380952
Cytomegalovirus nephritis 15.03 10.50 9 200176 134 42421016
Ejection fraction abnormal 15.03 10.50 24 200161 1271 42419879
Engraft failure 14.98 10.50 16 200169 567 42420583
Skin fissures 14.96 10.50 14 200171 9662 42411488
Orbital infection 14.93 10.50 7 200178 61 42421089
Critical illness 14.90 10.50 11 200174 236 42420914
Pulmonary cavitation 14.90 10.50 24 200161 1280 42419870
Mood altered 14.89 10.50 17 200168 10701 42410449
Feeding intolerance 14.87 10.50 12 200173 295 42420855
Bursitis infective 14.86 10.50 17 200168 651 42420499
Multiple-drug resistance 14.86 10.50 71 200114 7251 42413899
Meningitis bacterial 14.85 10.50 25 200160 1384 42419766
Accelerated idioventricular rhythm 14.82 10.50 10 200175 185 42420965
Listeriosis 14.82 10.50 25 200160 1386 42419764
Bacterial test positive 14.78 10.50 42 200143 3333 42417817
Disorientation 14.77 10.50 105 200080 36284 42384866
Urethral polyp 14.74 10.50 7 200178 63 42421087
Haemoperitoneum 14.71 10.50 31 200154 2035 42419115
Post procedural urine leak 14.69 10.50 9 200176 140 42421010
Multiple sclerosis relapse 14.68 10.50 116 200069 14148 42407002
Synovitis 14.68 10.50 32 200153 15535 42405615
Rotavirus infection 14.62 10.50 15 200170 507 42420643
Hepatic necrosis 14.58 10.50 46 200139 3867 42417283
Aplasia 14.58 10.50 53 200132 4790 42416360
Retinal scar 14.57 10.50 13 200172 368 42420782
Astrovirus test positive 14.55 10.50 6 200179 37 42421113
Tumefactive multiple sclerosis 14.55 10.50 7 200178 65 42421085
Herpes simplex reactivation 14.50 10.50 15 200170 512 42420638
Gastroenteritis Escherichia coli 14.45 10.50 20 200165 931 42420219
Acinetobacter test positive 14.41 10.50 9 200176 145 42421005
Blood test abnormal 14.38 10.50 24 200161 12882 42408268
Chronic kidney disease 14.37 10.50 147 200038 47094 42374056
Pulmonary arterial hypertension 14.32 10.50 16 200169 10171 42410979
Sopor 14.30 10.50 25 200160 13177 42407973
Skin test positive 14.30 10.50 14 200171 447 42420703
Oral bacterial infection 14.29 10.50 6 200179 39 42421111
Gastrointestinal mucormycosis 14.28 10.50 13 200172 378 42420772
Blood immunoglobulin A decreased 14.24 10.50 17 200168 682 42420468
Mucosal ulceration 14.24 10.50 24 200161 1330 42419820
Clostridium difficile infection 14.23 10.50 166 200019 22493 42398657
Infectious pleural effusion 14.22 10.50 40 200145 3155 42417995
Nervous system neoplasm 14.20 10.50 9 200176 149 42421001
Gastroenteritis rotavirus 14.11 10.50 12 200173 318 42420832
Blood cholesterol increased 14.11 10.50 71 200114 26670 42394480
Erosive duodenitis 14.11 10.50 28 200157 1761 42419389
Urinoma 14.11 10.50 11 200174 257 42420893
Arteritis infective 14.10 10.50 7 200178 70 42421080
Kidney rupture 14.07 10.50 10 200175 202 42420948
Vaccination failure 14.05 10.50 25 200160 1447 42419703
Kaposi's sarcoma 14.05 10.50 18 200167 777 42420373
Perforation bile duct 14.02 10.50 7 200178 71 42421079
Clostridium colitis 14.01 10.50 26 200159 1555 42419595
Ventricular extrasystoles 13.93 10.50 26 200159 13364 42407786
Trichophytosis 13.92 10.50 13 200172 391 42420759
Mitral valve incompetence 13.87 10.50 36 200149 16453 42404697
Sickle cell anaemia with crisis 13.86 10.50 3 200182 4887 42416263
Hypoaesthesia 13.86 10.50 244 199941 71219 42349931
Hyperlipidaemia 13.86 10.50 53 200132 21463 42399687
Gallbladder rupture 13.80 10.50 18 200167 791 42420359
Hepatocellular injury 13.79 10.50 171 200014 23507 42397643
Retching 13.73 10.50 10 200175 7811 42413339
Abdominal infection 13.72 10.50 34 200151 2485 42418665
Hiatus hernia 13.70 10.50 12 200173 8548 42412602
Prostate cancer metastatic 13.69 10.50 7 200178 6622 42414528
Oral candidiasis 13.67 10.50 115 200070 14290 42406860
Eye infection fungal 13.65 10.50 14 200171 473 42420677
Dizziness postural 13.64 10.50 10 200175 7785 42413365
Restless legs syndrome 13.63 10.50 15 200170 9599 42411551
Frequent bowel movements 13.61 10.50 53 200132 21354 42399796
Enthesopathy 13.61 10.50 3 200182 4825 42416325
Heart rate irregular 13.61 10.50 125 200060 15925 42405225
Foetal growth restriction 13.59 10.50 55 200130 5228 42415922
Renal haemorrhage 13.57 10.50 26 200159 1593 42419557
MAGIC syndrome 13.56 10.50 6 200179 45 42421105
Gastroenteritis clostridial 13.54 10.50 13 200172 405 42420745
Productive cough 13.50 10.50 166 200019 51401 42369749
Mesenteric haemorrhage 13.50 10.50 5 200180 22 42421128
Granulomatous lymphadenitis 13.49 10.50 10 200175 216 42420934
Osteosarcoma recurrent 13.48 10.50 8 200177 117 42421033
Vasculitis gastrointestinal 13.45 10.50 6 200179 46 42421104
Meningitis aseptic 13.45 10.50 49 200136 4433 42416717
Gastrointestinal perforation 13.43 10.50 49 200136 4437 42416713
Conjunctival hyperaemia 13.40 10.50 39 200146 3137 42418013
Uraemic encephalopathy 13.38 10.50 13 200172 411 42420739
Papillitis 13.37 10.50 7 200178 79 42421071
Bacillus infection 13.35 10.50 17 200168 729 42420421
B-lymphocyte count increased 13.34 10.50 6 200179 47 42421103
Abscess sterile 13.32 10.50 5 200180 23 42421127
Cervical spinal cord paralysis 13.32 10.50 5 200180 23 42421127
Hypoproteinaemia 13.31 10.50 36 200149 2776 42418374
Hip fracture 13.28 10.50 27 200158 13445 42407705
Hyperlactacidaemia 13.24 10.50 49 200136 4467 42416683
Central nervous system abscess 13.24 10.50 6 200179 48 42421102
Nephrotic syndrome 13.22 10.50 78 200107 8640 42412510
Madarosis 13.20 10.50 14 200171 492 42420658
Urinary fistula 13.19 10.50 8 200177 122 42421028
Pleural mass 13.15 10.50 7 200178 82 42421068
Musculoskeletal pain 13.14 10.50 97 200088 33243 42387907
Oral lichenoid reaction 13.14 10.50 8 200177 123 42421027
Cervical plexus lesion 13.10 10.50 3 200182 0 42421150
Lymphocytic infiltration 13.05 10.50 19 200166 927 42420223
Hypocalvaria 13.03 10.50 6 200179 50 42421100
Palatal ulcer 13.03 10.50 6 200179 50 42421100
Wheezing 13.00 10.50 180 200005 54601 42366549
Feeling hot 13.00 10.50 168 200017 23314 42397836
Gait inability 12.99 10.50 59 200126 22774 42398376
Norovirus infection 12.98 10.50 17 200168 750 42420400
Klebsiella bacteraemia 12.98 10.50 32 200153 2332 42418818
Short stature 12.97 10.50 13 200172 427 42420723
Cardiogenic shock 12.97 10.50 106 200079 35534 42385616
Central nervous system lesion 12.97 10.50 72 200113 7798 42413352
Iron deficiency anaemia 12.97 10.50 26 200159 13013 42408137
Blood lactate dehydrogenase increased 12.96 10.50 183 200002 25898 42395252
Surgery 12.96 10.50 41 200144 17575 42403575
Adenomatous polyposis coli 12.95 10.50 9 200176 175 42420975
Mycobacterium kansasii infection 12.93 10.50 12 200173 358 42420792
SJS-TEN overlap 12.88 10.50 16 200169 669 42420481
Abdominal wall abscess 12.86 10.50 16 200169 670 42420480
Weight decreased 12.84 10.50 823 199362 207125 42214025
Benign prostatic hyperplasia 12.83 10.50 53 200132 20999 42400151
Leishmaniasis 12.83 10.50 13 200172 433 42420717
Encephalomyelitis 12.81 10.50 8 200177 129 42421021
Libido decreased 12.79 10.50 4 200181 5094 42416056
Haemolysis 12.78 10.50 83 200102 9506 42411644
Intentional dose omission 12.76 10.50 14 200171 8972 42412178
Cardio-respiratory arrest 12.76 10.50 196 199989 58440 42362710
Cryptosporidiosis infection 12.64 10.50 17 200168 770 42420380
Thrombotic thrombocytopenic purpura 12.63 10.50 43 200142 3761 42417389
Urine leukocyte esterase positive 12.63 10.50 13 200172 441 42420709
Stupor 12.62 10.50 38 200147 3115 42418035
Angioedema 12.59 10.50 133 200052 42344 42378806
Lichenoid keratosis 12.55 10.50 44 200141 3906 42417244
Respiratory rate increased 12.53 10.50 92 200093 10970 42410180
Morganella infection 12.52 10.50 15 200170 604 42420546
Corneal lesion 12.51 10.50 7 200178 91 42421059
Foetal exposure during pregnancy 12.50 10.50 152 200033 47159 42373991
Toxoplasmosis 12.49 10.50 25 200160 1582 42419568
Therapeutic product effect prolonged 12.46 10.50 11 200174 307 42420843
Urine ketone body present 12.45 10.50 23 200162 1371 42419779
Diabetes mellitus 12.44 10.50 370 199815 59717 42361433
Deafness 12.40 10.50 27 200158 13113 42408037
Faecaloma 12.39 10.50 7 200178 6263 42414887
Clonal haematopoiesis 12.32 10.50 9 200176 190 42420960
Wolff-Parkinson-White syndrome 12.32 10.50 10 200175 248 42420902
Chimerism 12.32 10.50 10 200175 248 42420902
Diabetic neuropathy 12.29 10.50 3 200182 4499 42416651
Mood swings 12.26 10.50 14 200171 8812 42412338
Therapeutic product effect decreased 12.25 10.50 121 200064 39029 42382121
Optic nerve compression 12.23 10.50 4 200181 11 42421139
Peripheral artery aneurysm 12.22 10.50 14 200171 537 42420613
Pneumonia necrotising 12.21 10.50 20 200165 1082 42420068
Apallic syndrome 12.19 10.50 11 200174 316 42420834
Disseminated trichosporonosis 12.19 10.50 7 200178 96 42421054
Cytokine storm 12.19 10.50 18 200167 890 42420260
Diffuse mesangial sclerosis 12.18 10.50 6 200179 59 42421091
Chronic papillomatous dermatitis 12.18 10.50 6 200179 59 42421091
Arterial rupture 12.14 10.50 14 200171 541 42420609
Herpes simplex oesophagitis 12.12 10.50 10 200175 254 42420896
Capnocytophaga infection 12.09 10.50 8 200177 143 42421007
Folliculitis 12.09 10.50 55 200130 5503 42415647
Hepatic artery occlusion 12.06 10.50 7 200178 98 42421052
Complications of transplanted heart 12.05 10.50 11 200174 321 42420829
ADAMTS13 activity decreased 12.05 10.50 8 200177 144 42421006
Eye pruritus 12.01 10.50 22 200163 11390 42409760
Ileostomy 12.00 10.50 20 200165 1098 42420052
Hypophosphataemia 11.99 10.50 54 200131 20891 42400259
Febrile neutropenia 11.98 10.50 732 199453 184971 42236179
Peritoneal perforation 11.97 10.50 4 200181 12 42421138
Ovarian cancer metastatic 11.97 10.50 4 200181 12 42421138
Paraesthesia ear 11.97 10.50 5 200180 32 42421118
Band neutrophil percentage increased 11.94 10.50 7 200178 100 42421050
Peripheral vascular disorder 11.93 10.50 5 200180 5312 42415838
Amoebic dysentery 11.92 10.50 6 200179 62 42421088
Therapeutic response decreased 11.91 10.50 242 199943 36770 42384380
Unmasking of previously unidentified disease 11.89 10.50 21 200164 1208 42419942
Rib fracture 11.89 10.50 39 200146 16532 42404618
Injection site rash 11.84 10.50 6 200179 5706 42415444
Removal of renal transplant 11.84 10.50 5 200180 33 42421117
Neuromyotonia 11.84 10.50 5 200180 33 42421117
Spinal osteoarthritis 11.83 10.50 14 200171 8672 42412478
Cataract subcapsular 11.78 10.50 14 200171 559 42420591
Meningoencephalitis herpetic 11.78 10.50 19 200166 1015 42420135
Urinary casts 11.77 10.50 13 200172 479 42420671
Infective myositis 11.76 10.50 7 200178 103 42421047
Biopsy lymph gland 11.75 10.50 6 200179 64 42421086
Eye irritation 11.75 10.50 22 200163 11296 42409854
Inadequate aseptic technique in use of product 11.74 10.50 4 200181 13 42421137
Cerebral venous sinus thrombosis 11.72 10.50 16 200169 735 42420415
Infection masked 11.67 10.50 6 200179 65 42421085
Peliosis hepatis 11.67 10.50 6 200179 65 42421085
Vertigo 11.67 10.50 104 200081 34243 42386907
Pleocytosis 11.66 10.50 15 200170 650 42420500
Coombs direct test positive 11.66 10.50 11 200174 335 42420815
Arthritis fungal 11.64 10.50 7 200178 105 42421045
Prinzmetal angina 11.63 10.50 22 200163 1335 42419815
Depressed level of consciousness 11.61 10.50 157 200028 47813 42373337
Infective aortitis 11.60 10.50 5 200180 35 42421115
Cytomegalovirus gastrointestinal ulcer 11.59 10.50 7 200178 106 42421044
Megacolon 11.57 10.50 30 200155 2255 42418895
Prescribed underdose 11.57 10.50 19 200166 10263 42410887
Atrioventricular block 11.55 10.50 17 200168 9598 42411552
Histology abnormal 11.55 10.50 11 200174 339 42420811
Drug level below therapeutic 11.55 10.50 61 200124 6484 42414666
Visceral leishmaniasis 11.53 10.50 20 200165 1134 42420016
Multiple sclerosis 11.53 10.50 68 200117 7530 42413620
Renal lymphocele 11.52 10.50 6 200179 67 42421083
Herpes simplex colitis 11.51 10.50 4 200181 14 42421136
Necrotising bronchiolitis 11.51 10.50 4 200181 14 42421136
Exophthalmos 11.50 10.50 17 200168 841 42420309
Citrobacter infection 11.48 10.50 15 200170 660 42420490
C-reactive protein increased 11.48 10.50 385 199800 63175 42357975
Nail discomfort 11.48 10.50 5 200180 36 42421114
Bicytopenia 11.47 10.50 37 200148 3147 42418003
Urinary tract infection enterococcal 11.47 10.50 19 200166 1038 42420112
Erythema infectiosum 11.45 10.50 8 200177 157 42420993
Specific gravity urine decreased 11.44 10.50 6 200179 68 42421082
Arteritis coronary 11.36 10.50 6 200179 69 42421081
Product complaint 11.35 10.50 7 200178 5970 42415180
Hypocalcaemia 11.32 10.50 89 200096 30084 42391066
Chronic graft versus host disease in liver 11.29 10.50 15 200170 671 42420479
Haemoglobinuria 11.29 10.50 15 200170 671 42420479
Superinfection 11.28 10.50 35 200150 2916 42418234
Pancreatic carcinoma 11.24 10.50 17 200168 9489 42411661
Disseminated varicella zoster vaccine virus infection 11.22 10.50 6 200179 71 42421079
Chromaturia 11.22 10.50 38 200147 15951 42405199
Marrow hyperplasia 11.20 10.50 21 200164 1266 42419884
Bone marrow failure 11.19 10.50 218 199967 32875 42388275
Acne fulminans 11.18 10.50 10 200175 284 42420866
Pollakiuria 11.17 10.50 61 200124 22444 42398706
Granuloma 11.15 10.50 43 200142 3998 42417152
Cytomegalovirus duodenitis 11.14 10.50 6 200179 72 42421078
pH urine increased 11.14 10.50 6 200179 72 42421078
Blood bilirubin unconjugated increased 11.14 10.50 15 200170 680 42420470
Urine bilirubin decreased 11.14 10.50 5 200180 39 42421111
Conjunctivitis allergic 11.12 10.50 7 200178 5904 42415246
Extrapulmonary tuberculosis 11.11 10.50 8 200177 165 42420985
Renal artery perforation 11.10 10.50 4 200181 16 42421134
Carotid artery insufficiency 11.10 10.50 4 200181 16 42421134
Post infection glomerulonephritis 11.09 10.50 7 200178 115 42421035
Tumour lysis syndrome 11.05 10.50 156 200029 22075 42399075
Iron deficiency 11.05 10.50 22 200163 11039 42410111
Galactosaemia 11.03 10.50 3 200182 3 42421147
Septic vasculitis 11.03 10.50 3 200182 3 42421147
Increased ventricular preload 11.03 10.50 3 200182 3 42421147
Meningioma malignant 10.92 10.50 5 200180 41 42421109
Fibrosarcoma 10.92 10.50 5 200180 41 42421109
Dermatophytosis 10.92 10.50 10 200175 293 42420857
Lipohypertrophy 10.92 10.50 10 200175 293 42420857
Exposure via skin contact 10.89 10.50 5 200180 5033 42416117
Coronary artery occlusion 10.88 10.50 22 200163 10975 42410175
Pericardial fibrosis 10.86 10.50 8 200177 171 42420979
Glomerulonephropathy 10.86 10.50 9 200176 230 42420920
Angiocentric lymphoma 10.84 10.50 13 200172 524 42420626
Swelling of eyelid 10.84 10.50 28 200157 2100 42419050
Pneumonia herpes viral 10.84 10.50 7 200178 120 42421030
Protein urine 10.83 10.50 18 200167 986 42420164
Haemorrhagic pneumonia 10.82 10.50 8 200177 172 42420978
Tongue fungal infection 10.82 10.50 5 200180 42 42421108
Body height below normal 10.76 10.50 9 200176 233 42420917
Product dispensing error 10.74 10.50 12 200173 7627 42413523
Osteomyelitis blastomyces 10.73 10.50 4 200181 18 42421132
Microvillous inclusion disease 10.73 10.50 9 200176 234 42420916
Asphyxia 10.73 10.50 14 200171 8312 42412838
Intestinal obstruction 10.71 10.50 79 200106 27079 42394071
Gaze palsy 10.68 10.50 26 200159 1879 42419271
Cardiac murmur 10.66 10.50 28 200157 12747 42408403
Central nervous system vasculitis 10.65 10.50 14 200171 620 42420530
Amnesia 10.61 10.50 84 200101 28353 42392797
Computerised tomogram thorax abnormal 10.60 10.50 15 200170 713 42420437
Pseudopolyposis 10.59 10.50 6 200179 80 42421070
Self-induced vomiting 10.57 10.50 3 200182 4 42421146
Macrophage activation 10.57 10.50 3 200182 4 42421146
Pulmonary hypertension 10.57 10.50 66 200119 23503 42397647
Magnetic resonance imaging head abnormal 10.57 10.50 23 200162 1544 42419606
Inhibin B 10.56 10.50 4 200181 19 42421131
Conjunctival oedema 10.53 10.50 14 200171 627 42420523
Schizophrenia 10.53 10.50 21 200164 10529 42410621

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 2973.53 9.81 15478 560080 1484707 108529034
Cytomegalovirus infection 1833.69 9.81 1811 573747 52633 109961108
Drug ineffective for unapproved indication 1334.20 9.81 2119 573439 100719 109913022
Completed suicide 1113.20 9.81 32 575526 242349 109771392
Drug ineffective 984.36 9.81 12140 563418 1508400 108505341
Transplant rejection 824.72 9.81 816 574742 23751 109989990
Blood pressure fluctuation 821.77 9.81 1431 574127 73393 109940348
Infusion related reaction 818.78 9.81 4037 571521 377125 109636616
Toxicity to various agents 762.38 9.81 826 574732 479729 109534012
Death 716.24 9.81 1613 573945 697256 109316485
Aspergillus infection 703.48 9.81 764 574794 24852 109988889
Bronchopulmonary aspergillosis 684.67 9.81 811 574747 29052 109984689
Blood pressure diastolic abnormal 667.51 9.81 746 574812 25069 109988672
Drug abuse 658.16 9.81 76 575482 177335 109836406
Cytomegalovirus viraemia 643.07 9.81 615 574943 17149 109996592
Blood pressure systolic abnormal 630.38 9.81 711 574847 24139 109989602
Throat irritation 608.69 9.81 1040 574518 52512 109961229
Pneumocystis jirovecii pneumonia 542.15 9.81 872 574686 41863 109971878
Multiple organ dysfunction syndrome 535.51 9.81 1873 573685 149837 109863904
Polyomavirus-associated nephropathy 528.94 9.81 396 575162 7805 110005936
Product use in unapproved indication 526.18 9.81 4056 571502 443321 109570420
Blood pressure systolic increased 522.57 9.81 1261 574297 81730 109932011
Posterior reversible encephalopathy syndrome 521.45 9.81 756 574802 33105 109980636
Product dose omission issue 517.87 9.81 546 575012 321236 109692505
Intentional overdose 500.96 9.81 53 575505 132448 109881293
Post transplant lymphoproliferative disorder 499.02 9.81 505 575053 15108 109998633
Epstein-Barr virus infection 488.77 9.81 544 575014 18194 109995547
Thrombotic microangiopathy 483.07 9.81 674 574884 28475 109985266
Mucormycosis 470.73 9.81 412 575146 10216 110003525
Oxygen saturation decreased 465.27 9.81 1832 573726 155150 109858591
Cytomegalovirus infection reactivation 457.29 9.81 520 575038 17813 109995928
Haemophagocytic lymphohistiocytosis 450.57 9.81 680 574878 30879 109982862
Respiratory failure 448.44 9.81 2262 573296 213070 109800671
Kidney transplant rejection 447.22 9.81 422 575136 11565 110002176
Blood pressure increased 425.85 9.81 2547 573011 255826 109757915
Enterococcal infection 421.15 9.81 525 575033 19841 109993900
BK virus infection 420.86 9.81 425 575133 12681 110001060
Injection site pain 419.94 9.81 200 575358 177722 109836019
Fall 390.50 9.81 1714 573844 601768 109411973
Heart rate decreased 361.57 9.81 1099 574459 81657 109932084
Lymphocyte count decreased 359.49 9.81 869 574689 56374 109957367
Strongyloidiasis 355.99 9.81 256 575302 4730 110009011
Septic shock 350.82 9.81 1687 573871 155841 109857900
Klebsiella infection 348.61 9.81 474 575084 19535 109994206
Rheumatoid arthritis 341.66 9.81 2698 572860 296915 109716826
Drug effective for unapproved indication 340.13 9.81 394 575164 13773 109999968
Nocardiosis 335.16 9.81 292 575266 7194 110006547
Dehydration 326.63 9.81 597 574961 278914 109734827
Pneumatosis intestinalis 317.68 9.81 300 575258 8229 110005512
Complications of transplanted kidney 312.66 9.81 280 575278 7162 110006579
Diarrhoea 310.81 9.81 4125 571433 1135380 108878361
Ear pruritus 310.66 9.81 276 575282 6984 110006757
Adenovirus infection 302.02 9.81 328 575230 10666 110003075
Steroid diabetes 295.74 9.81 234 575324 5020 110008721
Graft versus host disease 295.57 9.81 424 575134 18382 109995359
Pseudomonas infection 293.16 9.81 523 575035 27330 109986411
Graft versus host disease in gastrointestinal tract 288.30 9.81 291 575267 8677 110005064
Cardiac failure congestive 287.33 9.81 219 575339 150781 109862960
Urine abnormality 286.66 9.81 292 575266 8804 110004937
Blood pressure diastolic decreased 281.35 9.81 595 574963 35290 109978451
Vomiting 276.08 9.81 3222 572336 907453 109106288
Suicide attempt 269.99 9.81 100 575458 103294 109910447
Nausea 267.87 9.81 4675 570883 1231015 108782726
Myocardial infarction 266.28 9.81 366 575192 191717 109822024
Pulmonary nocardiosis 254.56 9.81 163 575395 2466 110011275
Wrong technique in product usage process 250.05 9.81 72 575486 87276 109926465
Pneumomediastinum 249.09 9.81 208 575350 4828 110008913
Syncope 247.05 9.81 421 575137 202115 109811626
Fatigue 245.05 9.81 4659 570899 1211299 108802442
Cytomegalovirus colitis 241.54 9.81 237 575321 6824 110006917
Candida infection 234.99 9.81 664 574894 47345 109966396
Injection site erythema 232.91 9.81 99 575459 94077 109919664
Human herpesvirus 6 infection 230.94 9.81 224 575334 6357 110007384
Pneumonia cytomegaloviral 229.70 9.81 229 575329 6725 110007016
Cytomegalovirus test positive 229.28 9.81 230 575328 6806 110006935
Drug interaction 225.78 9.81 1599 573959 498584 109515157
Acute graft versus host disease in skin 222.28 9.81 277 575281 10463 110003278
Hospitalisation 222.16 9.81 248 575310 142245 109871496
Hypoglycaemia 221.38 9.81 168 575390 115936 109897805
White blood cells urine positive 216.40 9.81 230 575328 7294 110006447
Red blood cells urine positive 215.69 9.81 194 575364 4991 110008750
Urine leukocyte esterase positive 211.77 9.81 168 575390 3618 110010123
Delayed graft function 208.85 9.81 175 575383 4082 110009659
Orthostatic hypotension 208.24 9.81 45 575513 66204 109947537
Hyponatraemia 200.53 9.81 530 575028 217123 109796618
Acute respiratory distress syndrome 199.99 9.81 671 574887 52527 109961214
Rebound effect 198.63 9.81 310 575248 14496 109999245
Oedema peripheral 198.23 9.81 957 574601 327703 109686038
Immunosuppressant drug level increased 197.10 9.81 273 575285 11451 110002290
Progressive multifocal leukoencephalopathy 197.04 9.81 415 575143 24541 109989200
Constipation 194.30 9.81 1080 574478 356706 109657035
Graft versus host disease in skin 192.22 9.81 226 575332 8028 110005713
Disease recurrence 191.93 9.81 724 574834 60060 109953681
Sedation 191.23 9.81 62 575496 69621 109944120
COVID-19 190.32 9.81 2032 573526 243028 109770713
Heart rate increased 189.68 9.81 1341 574217 142493 109871248
Urinary sediment present 187.85 9.81 133 575425 2395 110011346
Cushingoid 186.91 9.81 266 575292 11446 110002295
Decreased appetite 186.22 9.81 1582 573976 474264 109539477
Pharyngeal paraesthesia 184.64 9.81 161 575397 3971 110009770
Escherichia infection 184.51 9.81 393 575165 23423 109990318
Disseminated intravascular coagulation 182.84 9.81 551 575007 40735 109973006
Malignant neoplasm progression 182.26 9.81 398 575160 174169 109839572
Dizziness 181.99 9.81 2549 573009 695644 109318097
Systemic candida 180.95 9.81 241 575317 9733 110004008
Crystal urine present 180.33 9.81 118 575440 1856 110011885
Cystitis haemorrhagic 177.01 9.81 265 575293 11944 110001797
Dyspnoea 176.99 9.81 4399 571159 1102473 108911268
Lymphopenia 174.05 9.81 532 575026 39638 109974103
Varicella zoster virus infection 173.20 9.81 189 575369 6179 110007562
Hypogammaglobulinaemia 172.84 9.81 346 575212 19730 109994011
Parvovirus B19 infection 172.31 9.81 133 575425 2748 110010993
Overdose 169.11 9.81 635 574923 233159 109780582
Injection site swelling 166.02 9.81 57 575501 61733 109952008
Herpes simplex 165.89 9.81 296 575262 15468 109998273
Enterobacter infection 164.24 9.81 176 575382 5635 110008106
Accidental exposure to product 163.35 9.81 31 575527 49977 109963764
Pulmonary mucormycosis 162.15 9.81 114 575444 2029 110011712
Secondary immunodeficiency 161.91 9.81 158 575400 4518 110009223
Neutrophil percentage increased 160.83 9.81 161 575397 4752 110008989
Lymphocyte percentage decreased 159.27 9.81 166 575392 5144 110008597
Myopathy 154.63 9.81 377 575181 24583 109989158
Full blood count abnormal 151.83 9.81 51 575507 56001 109957740
Acinetobacter infection 149.25 9.81 134 575424 3439 110010302
Rhabdomyolysis 147.95 9.81 249 575309 120152 109893589
International normalised ratio increased 146.56 9.81 141 575417 86631 109927110
Polyomavirus viraemia 146.52 9.81 131 575427 3343 110010398
Systemic mycosis 145.13 9.81 136 575422 3693 110010048
Accidental overdose 144.22 9.81 45 575513 51789 109961952
Erythema 143.59 9.81 2222 573336 289225 109724516
Therapy interrupted 140.89 9.81 42 575516 49780 109963961
Acute graft versus host disease in intestine 140.72 9.81 160 575398 5479 110008262
Transient ischaemic attack 140.39 9.81 79 575479 63903 109949838
Serotonin syndrome 140.27 9.81 66 575492 59087 109954654
Blood pressure diastolic increased 139.57 9.81 305 575253 18502 109995239
Liver transplant rejection 138.69 9.81 134 575424 3784 110009957
Device expulsion 138.44 9.81 5 575553 30886 109982855
Injection site bruising 138.23 9.81 47 575511 51216 109962525
Urine analysis abnormal 138.14 9.81 175 575383 6722 110007019
Chronic allograft nephropathy 137.86 9.81 103 575455 2023 110011718
Temperature regulation disorder 137.75 9.81 243 575315 12583 110001158
Infection reactivation 135.92 9.81 135 575423 3946 110009795
Renal transplant failure 135.27 9.81 112 575446 2568 110011173
Osteonecrosis 134.35 9.81 434 575124 33307 109980434
Coeliac disease 134.35 9.81 512 575046 42675 109971066
Intentional self-injury 133.96 9.81 18 575540 37411 109976330
Suicidal ideation 130.12 9.81 179 575379 93758 109919983
Injection site pruritus 129.78 9.81 52 575506 51206 109962535
Disseminated mucormycosis 127.82 9.81 98 575460 2004 110011737
Stenotrophomonas infection 127.55 9.81 155 575403 5703 110008038
COVID-19 pneumonia 127.00 9.81 454 575104 36689 109977052
Coronary artery disease 125.19 9.81 113 575445 71577 109942164
Mycobacterium chelonae infection 124.35 9.81 113 575445 2947 110010794
Acute graft versus host disease 124.33 9.81 233 575325 12648 110001093
Cerebrovascular accident 124.27 9.81 503 575055 180781 109832960
Venoocclusive disease 123.84 9.81 159 575399 6191 110007550
Hypertension 121.44 9.81 3495 572063 506589 109507152
Loss of personal independence in daily activities 120.89 9.81 389 575169 149631 109864110
Multiple sclerosis relapse 120.52 9.81 550 575008 49690 109964051
Acute kidney injury 120.08 9.81 2459 573099 632971 109380770
Cryptococcosis 120.00 9.81 134 575424 4497 110009244
Onychomadesis 119.46 9.81 513 575045 45150 109968591
Poisoning deliberate 118.92 9.81 4 575554 26327 109987414
Cytomegalovirus enteritis 117.36 9.81 72 575486 1006 110012735
Drug resistance 116.35 9.81 591 574967 55783 109957958
Penicillium infection 115.84 9.81 60 575498 591 110013150
Cytomegalovirus chorioretinitis 112.44 9.81 161 575397 6967 110006774
Reversible cerebral vasoconstriction syndrome 111.93 9.81 131 575427 4630 110009111
Somnolence 111.32 9.81 1000 574558 296449 109717292
Onychomycosis 110.29 9.81 445 575113 38086 109975655
Central nervous system viral infection 109.71 9.81 47 575511 287 110013454
Device issue 109.47 9.81 23 575535 34512 109979229
Flushing 108.86 9.81 924 574634 103812 109909929
Bacterial sepsis 108.72 9.81 195 575363 10231 110003510
Confusional state 108.19 9.81 1751 573807 466929 109546812
Anaemia 107.86 9.81 2102 573456 544984 109468757
Intentional product use issue 106.82 9.81 1849 573709 246057 109767684
Viraemia 106.82 9.81 119 575439 3983 110009758
C-reactive protein increased 106.74 9.81 1660 573898 216259 109797482
Neuropathy peripheral 106.28 9.81 525 575033 178752 109834989
Epstein-Barr virus associated lymphoproliferative disorder 106.09 9.81 128 575430 4674 110009067
Depressed level of consciousness 105.97 9.81 270 575288 112008 109901733
Nightmare 105.89 9.81 35 575523 38828 109974913
Lethargy 105.57 9.81 204 575354 93372 109920369
Dry skin 105.42 9.81 254 575304 107399 109906342
Alopecia 105.32 9.81 1303 574255 363450 109650291
Myalgia 102.58 9.81 706 574852 221675 109792066
Acute graft versus host disease in liver 101.57 9.81 90 575468 2269 110011472
Medication error 101.29 9.81 251 575307 105115 109908626
Bacterial test 101.18 9.81 68 575490 1121 110012620
Asthenia 100.85 9.81 2772 572786 686227 109327514
Focal segmental glomerulosclerosis 100.71 9.81 116 575442 4029 110009712
Leukopenia 100.60 9.81 1201 574357 147590 109866151
Diffuse alveolar damage 99.58 9.81 114 575444 3933 110009808
JC virus infection 99.33 9.81 130 575428 5160 110008581
Therapy non-responder 98.26 9.81 1251 574307 156056 109857685
Sopor 97.69 9.81 34 575524 36512 109977229
Neuroleptic malignant syndrome 97.61 9.81 28 575530 34031 109979710
Hyperkalaemia 97.39 9.81 370 575188 135426 109878315
Loss of consciousness 97.22 9.81 610 574948 195696 109818045
Electrocardiogram QT prolonged 96.80 9.81 270 575288 108690 109905051
Food allergy 96.73 9.81 275 575283 19673 109994068
Viral haemorrhagic cystitis 96.16 9.81 103 575455 3296 110010445
Osteonecrosis of jaw 96.06 9.81 66 575492 47951 109965790
Immunodeficiency 96.02 9.81 429 575129 38409 109975332
Plasma cell myeloma 95.40 9.81 112 575446 62824 109950917
Staphylococcal sepsis 94.97 9.81 251 575307 17203 109996538
Atrial fibrillation 94.93 9.81 752 574806 228890 109784851
Immunosuppressant drug level decreased 94.77 9.81 93 575465 2678 110011063
Therapy cessation 94.72 9.81 58 575500 44799 109968942
Device malfunction 94.61 9.81 11 575547 25547 109988194
Product prescribing error 93.16 9.81 78 575480 51253 109962488
Bacteraemia 92.15 9.81 451 575107 41939 109971802
Fungal infection 92.12 9.81 514 575044 50292 109963449
Unresponsive to stimuli 91.97 9.81 118 575440 63672 109950069
Chorioretinopathy 91.80 9.81 84 575474 2211 110011530
Intensive care unit acquired weakness 91.75 9.81 85 575473 2274 110011467
Ureaplasma infection 91.65 9.81 71 575487 1475 110012266
Poisoning 91.00 9.81 20 575538 29085 109984656
Intentional product misuse 90.93 9.81 369 575189 132535 109881206
Bacterial test positive 90.72 9.81 155 575403 7822 110005919
Pneumonia klebsiella 89.16 9.81 139 575419 6493 110007248
Chest pain 88.88 9.81 1400 574158 374975 109638766
Gastroenteritis norovirus 87.64 9.81 101 575457 3510 110010231
Contusion 87.53 9.81 784 574774 232577 109781164
Protein urine present 87.23 9.81 188 575370 11296 110002445
Hypophagia 87.15 9.81 87 575471 52539 109961202
Pneumocystis jirovecii infection 87.11 9.81 111 575447 4289 110009452
Perinephric abscess 86.62 9.81 43 575515 384 110013357
Malacoplakia 86.46 9.81 63 575495 1189 110012552
Multiple sclerosis 86.06 9.81 312 575246 25386 109988355
Blood urine present 86.03 9.81 300 575258 23945 109989796
Red cell distribution width increased 85.68 9.81 243 575315 17359 109996382
Hyperglycaemia 84.93 9.81 744 574814 84346 109929395
Nephropathy toxic 84.84 9.81 325 575233 27153 109986588
Human herpesvirus 8 infection 83.80 9.81 73 575485 1798 110011943
Corynebacterium infection 83.52 9.81 75 575483 1925 110011816
Disseminated cryptococcosis 83.19 9.81 85 575473 2572 110011169
Lupus nephritis 82.37 9.81 111 575447 4534 110009207
Serum sickness 82.30 9.81 108 575450 4298 110009443
Pneumonia bacterial 82.23 9.81 312 575246 25949 109987792
Incorrect dose administered 81.92 9.81 271 575287 103370 109910371
Substance-induced psychotic disorder 81.89 9.81 120 575438 5304 110008437
Peripheral swelling 81.83 9.81 1545 574013 402489 109611252
Condition aggravated 81.75 9.81 4639 570919 730197 109283544
Swollen tongue 81.62 9.81 117 575441 60245 109953496
Obstructive airways disorder 81.47 9.81 72 575486 46077 109967664
Feeling abnormal 81.22 9.81 578 574980 180133 109833608
Urine ketone body present 80.88 9.81 100 575458 3746 110009995
Blepharospasm 80.38 9.81 525 575033 54326 109959415
Coma 80.16 9.81 328 575230 117541 109896200
Injection site haemorrhage 79.63 9.81 36 575522 32992 109980749
Graft versus host disease in liver 79.26 9.81 80 575478 2385 110011356
Opportunistic infection 79.19 9.81 95 575463 3448 110010293
Granulomatosis with polyangiitis 78.69 9.81 94 575464 3396 110010345
Device difficult to use 78.01 9.81 5 575553 18800 109994941
Full blood count decreased 77.37 9.81 35 575523 32064 109981677
Candida sepsis 77.28 9.81 86 575472 2875 110010866
Pneumonia cryptococcal 77.20 9.81 80 575478 2462 110011279
Bursitis 76.86 9.81 1023 574535 128895 109884846
Prostate cancer 76.28 9.81 51 575507 37590 109976151
Haemoglobin urine present 76.20 9.81 52 575506 880 110012861
Human bocavirus infection 76.18 9.81 56 575502 1072 110012669
Back injury 75.87 9.81 464 575094 46935 109966806
Rhinocerebral mucormycosis 75.74 9.81 63 575495 1454 110012287
Disseminated aspergillosis 75.23 9.81 78 575480 2402 110011339
Injection site mass 74.78 9.81 18 575540 24595 109989146
Hypercholesterolaemia 74.10 9.81 761 574797 90076 109923665
Cardiac failure 74.06 9.81 622 574936 187004 109826737
Nail disorder 73.35 9.81 535 575023 57400 109956341
Sleep disorder due to general medical condition, insomnia type 72.46 9.81 293 575265 105350 109908391
Pneumonia acinetobacter 72.17 9.81 37 575521 356 110013385
Chronic graft versus host disease 72.04 9.81 155 575403 9302 110004439
Epstein-Barr viraemia 71.98 9.81 91 575467 3488 110010253
Heart transplant rejection 71.31 9.81 69 575489 1952 110011789
Pulmonary alveolar haemorrhage 71.21 9.81 249 575309 19901 109993840
Pain 70.86 9.81 4158 571400 950797 109062944
Red blood cell sedimentation rate abnormal 70.51 9.81 20 575538 24489 109989252
Respiratory arrest 70.29 9.81 122 575436 58177 109955564
Carotid artery thrombosis 70.04 9.81 155 575403 9483 110004258
Disseminated varicella zoster virus infection 69.85 9.81 56 575502 1225 110012516
Renal tubular atrophy 69.79 9.81 72 575486 2204 110011537
Respiratory rate increased 69.66 9.81 287 575271 24796 109988945
Chest discomfort 69.31 9.81 1281 574277 172567 109841174
Oral pruritus 69.30 9.81 86 575472 3234 110010507
Neurologic neglect syndrome 69.23 9.81 151 575407 9147 110004594
Hallucination 69.14 9.81 282 575276 101150 109912591
Monocyte percentage increased 69.08 9.81 72 575486 2231 110011510
Febrile neutropenia 68.93 9.81 1196 574362 315571 109698170
Rectal haemorrhage 68.69 9.81 355 575203 119478 109894263
Needle issue 67.76 9.81 7 575551 17833 109995908
Sedation complication 67.70 9.81 11 575547 19844 109993897
Glomerulonephritis 67.62 9.81 102 575456 4628 110009113
Epstein-Barr virus infection reactivation 67.01 9.81 94 575464 3990 110009751
Scedosporium infection 66.93 9.81 73 575485 2385 110011356
Blood calcium decreased 66.87 9.81 53 575505 35792 109977949
Specific gravity urine decreased 66.73 9.81 47 575511 839 110012902
Cytomegalovirus enterocolitis 66.08 9.81 70 575488 2211 110011530
Product storage error 65.80 9.81 16 575542 21712 109992029
Arterial occlusive disease 65.62 9.81 202 575356 15106 109998635
Dyspnoea exertional 65.61 9.81 298 575260 103762 109909979
Mycobacterium abscessus infection 65.44 9.81 61 575497 1645 110012096
Drug withdrawal syndrome 65.23 9.81 61 575497 37993 109975748
Culture urine positive 65.15 9.81 101 575457 4695 110009046
Chronic obstructive pulmonary disease 65.06 9.81 319 575239 108839 109904902
Necrotising retinitis 64.98 9.81 59 575499 1537 110012204
Staphylococcal bacteraemia 64.95 9.81 213 575345 16475 109997266
Staphylococcal infection 64.90 9.81 602 574956 69342 109944399
Pleocytosis 64.89 9.81 61 575497 1663 110012078
Labelled drug-drug interaction medication error 64.54 9.81 36 575522 29266 109984475
Surgery 64.16 9.81 72 575486 41211 109972530
Blood immunoglobulin G decreased 62.83 9.81 106 575452 5294 110008447
Finger deformity 62.82 9.81 339 575219 32753 109980988
Swelling 62.80 9.81 1370 574188 349671 109664070
Central nervous system infection 62.75 9.81 60 575498 1672 110012069
Bone pain 62.72 9.81 155 575403 64978 109948763
Cardiac disorder 62.69 9.81 196 575362 76084 109937657
Discomfort 62.67 9.81 765 574793 213942 109799799
Dyskinesia 62.63 9.81 107 575451 51339 109962402
Infective aneurysm 62.41 9.81 56 575502 1436 110012305
Sensory loss 62.36 9.81 249 575309 21208 109992533
Thrombosis 62.23 9.81 322 575236 108340 109905401
Cerebral aspergillosis 62.05 9.81 68 575490 2234 110011507
Anaphylactic shock 61.85 9.81 470 575088 51076 109962665
Acute myocardial infarction 61.54 9.81 226 575332 83551 109930190
Disseminated tuberculosis 61.19 9.81 102 575456 5044 110008697
Dural arteriovenous fistula 60.89 9.81 22 575536 78 110013663
Pseudomonal sepsis 60.75 9.81 141 575417 8905 110004836
Body temperature decreased 60.02 9.81 363 575195 36572 109977169
Toxoplasmosis 59.89 9.81 79 575479 3160 110010581
Transplant failure 59.53 9.81 106 575452 5529 110008212
Drug intolerance 59.49 9.81 1635 573923 404877 109608864
Pulmonary embolism 59.30 9.81 773 574785 213701 109800040
Device leakage 59.17 9.81 7 575551 16041 109997700
Palmar-plantar erythrodysaesthesia syndrome 59.02 9.81 76 575482 40949 109972792
Central nervous system fungal infection 58.88 9.81 38 575520 583 110013158
Cardio-respiratory arrest 58.86 9.81 357 575201 115479 109898262
Torsade de pointes 58.75 9.81 22 575536 22578 109991163
Extrapyramidal disorder 58.65 9.81 39 575519 28828 109984913
Osteomyelitis fungal 58.40 9.81 33 575525 392 110013349
Immune thrombocytopenia 58.28 9.81 252 575306 22242 109991499
Pneumonia fungal 58.03 9.81 189 575369 14565 109999176
Device dislocation 57.75 9.81 48 575510 31656 109982085
Aggression 57.73 9.81 140 575418 59070 109954671
Premature delivery 57.61 9.81 313 575245 30319 109983422
Kidney fibrosis 57.58 9.81 91 575467 4301 110009440
Encephalitis 57.49 9.81 222 575336 18617 109995124
Injection site rash 57.29 9.81 25 575533 23394 109990347
Gastroenteritis rotavirus 57.15 9.81 37 575521 571 110013170
Abdominal discomfort 57.14 9.81 1586 573972 392272 109621469
Gangrene 56.94 9.81 201 575357 16140 109997601
Necrosis ischaemic 56.83 9.81 51 575507 1308 110012433
Diffuse large B-cell lymphoma 56.65 9.81 197 575361 15701 109998040
Injection site warmth 56.40 9.81 11 575547 17394 109996347
Pain in extremity 56.31 9.81 2021 573537 485097 109528644
Intra-abdominal pressure increased 56.14 9.81 31 575527 351 110013390
Type I hypersensitivity 56.01 9.81 111 575447 6282 110007459
Graft loss 55.86 9.81 50 575508 1278 110012463
Herpes zoster 55.50 9.81 832 574726 107547 109906194
Haemolytic anaemia 55.46 9.81 236 575322 20684 109993057
Unevaluable event 55.44 9.81 143 575415 59084 109954657
Herpes simplex pneumonia 55.32 9.81 31 575527 362 110013379
Tardive dyskinesia 55.19 9.81 4 575554 13575 110000166
Proteinuria 55.01 9.81 377 575181 39641 109974100
Epistaxis 54.75 9.81 425 575133 129947 109883794
Electric shock 54.56 9.81 57 575501 1771 110011970
Oedema 54.37 9.81 767 574791 209209 109804532
Flatulence 54.31 9.81 119 575439 52030 109961711
Specific gravity urine increased 54.16 9.81 34 575524 496 110013245
Large intestine perforation 54.09 9.81 200 575358 16429 109997312
Herpes virus infection 54.07 9.81 131 575427 8507 110005234
Enterocolitis viral 53.41 9.81 41 575517 840 110012901
Cutaneous mucormycosis 53.31 9.81 38 575520 692 110013049
Sepsis 53.19 9.81 2146 573412 325200 109688541
Epilepsy 53.16 9.81 774 574784 99435 109914306
Immunosuppression 53.15 9.81 208 575350 17551 109996190
Nitrite urine present 52.94 9.81 47 575511 1188 110012553
Cryptococcal meningoencephalitis 52.83 9.81 30 575528 360 110013381
Product substitution issue 52.75 9.81 27 575531 23034 109990707
Protothecosis 52.61 9.81 34 575524 523 110013218
Urinary retention 52.49 9.81 186 575372 69497 109944244
Skin striae 52.48 9.81 61 575497 2140 110011601
Parkinsonism 52.23 9.81 25 575533 22162 109991579
Cholelithiasis 52.09 9.81 163 575395 63259 109950482
Malaise 51.75 9.81 2914 572644 668905 109344836
Fungaemia 51.32 9.81 104 575454 5982 110007759
Hepatitis 51.16 9.81 704 574854 89350 109924391
Angioedema 50.88 9.81 302 575256 98198 109915543
Infective pulmonary exacerbation of cystic fibrosis 50.78 9.81 8 575550 14763 109998978
New onset diabetes after transplantation 50.70 9.81 30 575528 391 110013350
Bacterial infection 50.42 9.81 411 575147 45625 109968116
Pulmonary hypertension 50.41 9.81 135 575423 55085 109958656
Haemolytic uraemic syndrome 50.41 9.81 92 575466 4893 110008848
Cystitis bacterial 50.39 9.81 46 575512 1207 110012534
Arteriosclerosis coronary artery 49.61 9.81 35 575523 25083 109988658
Respiratory depression 49.52 9.81 56 575502 31945 109981796
Systemic inflammatory response syndrome 49.44 9.81 165 575393 12878 110000863
Metastases to liver 49.43 9.81 67 575491 35319 109978422
Lung neoplasm malignant 49.41 9.81 62 575496 33780 109979961
Blood immunoglobulin M decreased 49.39 9.81 57 575501 1984 110011757
Cytomegalovirus oesophagitis 49.34 9.81 41 575517 945 110012796
Disseminated blastomycosis 49.28 9.81 31 575527 454 110013287
Lip swelling 49.24 9.81 120 575438 50547 109963194
Haematemesis 49.20 9.81 151 575407 58957 109954784
Cytomegalovirus gastrointestinal infection 49.02 9.81 36 575522 688 110013053
Pneumoretroperitoneum 49.02 9.81 23 575535 179 110013562
Pyrexia 49.00 9.81 5365 570193 892900 109120841
Foetal death 48.90 9.81 189 575369 15856 109997885
Adverse drug reaction 48.71 9.81 335 575223 105224 109908517
Demyelination 48.69 9.81 133 575425 9296 110004445
Transplant dysfunction 48.64 9.81 123 575435 8205 110005536
Eczema 48.63 9.81 202 575356 72091 109941650
Neutrophil count increased 48.55 9.81 328 575230 34324 109979417
Therapy partial responder 48.51 9.81 345 575213 36716 109977025
Coordination abnormal 48.27 9.81 259 575299 24969 109988772
Brain abscess 48.17 9.81 108 575450 6666 110007075
Pathogen resistance 48.13 9.81 201 575357 17471 109996270
Gait disturbance 47.96 9.81 1092 574466 277116 109736625
Oral herpes 47.88 9.81 337 575221 35743 109977998
Pulmonary haemorrhage 47.85 9.81 191 575367 16265 109997476
Disorientation 47.83 9.81 197 575361 70474 109943267
Schizophrenia 47.81 9.81 27 575531 21799 109991942
Adjustment disorder 47.72 9.81 144 575414 10651 110003090
Pain in jaw 47.57 9.81 124 575434 51053 109962688
Aplastic anaemia 47.49 9.81 251 575307 24057 109989684
Encephalitis cytomegalovirus 47.33 9.81 54 575504 1856 110011885
Feeling hot 46.88 9.81 700 574858 90406 109923335
Phaeohyphomycosis 46.84 9.81 51 575507 1663 110012078
Necrotising herpetic retinopathy 46.69 9.81 22 575536 173 110013568
Mycotic endophthalmitis 46.55 9.81 29 575529 417 110013324
Fungal skin infection 46.52 9.81 111 575447 7138 110006603
Subcutaneous emphysema 46.20 9.81 62 575496 2522 110011219
Rheumatoid factor positive 46.01 9.81 450 575108 131190 109882551
Dystonia 45.86 9.81 40 575518 25765 109987976
Norovirus test positive 45.79 9.81 39 575519 931 110012810
Hemiplegia 45.72 9.81 237 575321 22545 109991196
Withdrawal syndrome 45.28 9.81 58 575500 31322 109982419
Blood parathyroid hormone decreased 45.20 9.81 7 575551 13082 110000659
Abdominal pain 44.98 9.81 2196 573362 510793 109502948
Cerebral fungal infection 44.94 9.81 34 575524 681 110013060
Hospice care 44.63 9.81 6 575552 12467 110001274
Ureteric stenosis 44.48 9.81 48 575510 1549 110012192
Epstein-Barr virus associated lymphoma 44.44 9.81 49 575509 1621 110012120
Injection site urticaria 44.34 9.81 17 575541 17198 109996543
Herpes simplex hepatitis 44.11 9.81 35 575523 754 110012987
Quadriplegia 44.07 9.81 78 575480 4049 110009692
Granuloma skin 43.98 9.81 4 575554 11279 110002462
Gastrointestinal mucormycosis 43.86 9.81 34 575524 707 110013034
Drug-induced liver injury 43.84 9.81 873 574685 119194 109894547
Neoplasm progression 43.76 9.81 180 575378 64415 109949326
Myoclonus 43.59 9.81 65 575493 32933 109980808
Listeriosis 43.57 9.81 63 575495 2751 110010990
Pregnancy 43.55 9.81 129 575429 50938 109962803
Tremor 43.50 9.81 765 574793 201467 109812274
Blood potassium increased 43.44 9.81 66 575492 33183 109980558
Throat tightness 43.40 9.81 311 575247 33178 109980563
Head injury 43.30 9.81 100 575458 42917 109970824
Poor venous access 43.07 9.81 246 575312 24276 109989465
Renal tubular necrosis 43.02 9.81 289 575269 30186 109983555
Blood calcium increased 42.97 9.81 20 575538 18020 109995721
Hypokalaemia 42.90 9.81 679 574879 181769 109831972
General physical health deterioration 42.88 9.81 1793 573765 423502 109590239
Hypoalbuminaemia 42.86 9.81 278 575280 28696 109985045
Abscess bacterial 42.86 9.81 37 575521 900 110012841
Synovitis 42.80 9.81 1092 574466 273000 109740741
Symptom masked 42.66 9.81 51 575507 1844 110011897
Pneumonia pseudomonal 42.57 9.81 110 575448 7436 110006305
Oesophageal carcinoma 42.56 9.81 5 575553 11519 110002222
Thyrotoxic periodic paralysis 42.55 9.81 21 575537 185 110013556
Red blood cells urine 42.51 9.81 32 575526 636 110013105
Rash pruritic 42.45 9.81 317 575241 97752 109915989
Pulmonary tuberculosis 42.39 9.81 124 575434 9015 110004726
Enthesopathy 42.35 9.81 7 575551 12471 110001270
Akathisia 42.29 9.81 18 575540 17095 109996646
Glomerulosclerosis 42.08 9.81 42 575516 1235 110012506
Salivary hypersecretion 41.98 9.81 19 575539 17402 109996339
Cytokine release syndrome 41.73 9.81 554 575004 69752 109943989
Miosis 41.65 9.81 32 575526 21951 109991790
Intervertebral discitis 41.62 9.81 104 575454 6886 110006855
Amoebic colitis 41.47 9.81 18 575540 114 110013627
Human polyomavirus infection 41.40 9.81 49 575509 1753 110011988
Neuromyelitis optica spectrum disorder 41.26 9.81 45 575513 1470 110012271
Creatinine renal clearance decreased 41.02 9.81 32 575526 21783 109991958
Febrile bone marrow aplasia 40.99 9.81 190 575368 17275 109996466
B-lymphocyte count decreased 40.93 9.81 52 575506 2003 110011738
West Nile viral infection 40.75 9.81 42 575516 1284 110012457
Cerebral venous thrombosis 40.59 9.81 66 575492 3196 110010545
Nephrotic syndrome 40.59 9.81 161 575397 13670 110000071
Steroid withdrawal syndrome 40.58 9.81 36 575522 909 110012832
Asthma 40.48 9.81 992 574566 249299 109764442
Peripheral venous disease 40.48 9.81 639 574919 83478 109930263
Parvovirus infection 40.38 9.81 36 575522 915 110012826
Pneumonia necrotising 40.34 9.81 48 575510 1727 110012014
Depressed mood 40.23 9.81 171 575387 60638 109953103
Renal tubular injury 40.20 9.81 64 575494 3044 110010697
Atrioventricular block first degree 40.20 9.81 12 575546 14213 109999528
Neutropenic sepsis 40.20 9.81 61 575497 30685 109983056
Apoptosis 40.15 9.81 32 575526 694 110013047
Breast cancer 40.10 9.81 88 575470 38454 109975287
Seizure 39.88 9.81 862 574696 220323 109793418
Cataract 39.84 9.81 608 574950 78877 109934864
Meningitis cryptococcal 39.71 9.81 81 575477 4681 110009060
Right ventricular failure 39.53 9.81 46 575512 25908 109987833
Hypothyroidism 39.53 9.81 220 575338 72679 109941062
Intestinal obstruction 39.48 9.81 143 575415 53084 109960657
Dementia 39.36 9.81 65 575493 31608 109982133
Enterococcus test positive 39.23 9.81 61 575497 2843 110010898
Muscular weakness 39.21 9.81 1624 573934 246844 109766897
Immune reconstitution inflammatory syndrome 39.18 9.81 178 575380 16048 109997693
Dysgeusia 39.16 9.81 209 575349 69776 109943965
Erectile dysfunction 39.16 9.81 24 575534 18532 109995209
Feeding intolerance 39.12 9.81 39 575519 1145 110012596
Subdural haematoma 38.95 9.81 82 575476 36372 109977369
Mycoplasma infection 38.91 9.81 42 575516 1356 110012385
Insomnia 38.75 9.81 1509 574049 359081 109654660
Pyelonephritis fungal 38.65 9.81 23 575535 303 110013438
Electrocardiogram QRS complex prolonged 38.64 9.81 10 575548 13011 110000730
Product label confusion 38.21 9.81 225 575333 22452 109991289
Renal graft infection 38.17 9.81 32 575526 747 110012994
Personality disorder 38.13 9.81 150 575408 12687 110001054
Breast cancer female 38.11 9.81 9 575549 12459 110001282
Escherichia sepsis 38.10 9.81 129 575429 10143 110003598
Optic neuritis 37.89 9.81 136 575422 11011 110002730
Bilirubin urine present 37.89 9.81 23 575535 315 110013426
Arthropathy 37.87 9.81 1173 574385 286349 109727392
Joint injury 37.86 9.81 96 575462 39898 109973843
Sinus congestion 37.83 9.81 280 575278 30179 109983562
Neutropenia 37.62 9.81 1580 573978 373040 109640701
Abnormal dreams 37.57 9.81 10 575548 12770 110000971
Neurological decompensation 37.46 9.81 99 575459 6784 110006957
Wound infection 37.46 9.81 708 574850 95757 109917984
Intestinal perforation 37.38 9.81 211 575347 20733 109993008
Respiratory distress 37.33 9.81 534 575024 68340 109945401
Tinnitus 37.19 9.81 175 575383 60365 109953376
Presyncope 37.15 9.81 130 575428 48757 109964984
Paraesthesia ear 37.12 9.81 27 575531 508 110013233
Urticaria 37.11 9.81 2022 573536 316835 109696906
Troponin increased 37.07 9.81 61 575497 29705 109984036
Dissociation 37.03 9.81 4 575554 9838 110003903
Oesophageal candidiasis 36.91 9.81 138 575420 11396 110002345
Sneezing 36.91 9.81 289 575269 31695 109982046
Thrombocytopenia 36.85 9.81 2193 573365 346692 109667049
Hepatitis B 36.79 9.81 122 575436 9490 110004251
Segmental diverticular colitis 36.72 9.81 18 575540 156 110013585
Polychondritis 36.72 9.81 34 575524 909 110012832
Rhinitis allergic 36.70 9.81 24 575534 17898 109995843
Deep vein thrombosis 36.55 9.81 510 575048 139377 109874364
Abdominal abscess 36.53 9.81 115 575443 8704 110005037
Multiple-drug resistance 36.41 9.81 151 575407 13084 110000657
Pedal pulse abnormal 36.10 9.81 20 575538 228 110013513
Vasculitis 35.96 9.81 314 575244 35559 109978182
Hemiparesis 35.89 9.81 368 575190 43535 109970206
Herpes simplex colitis 35.89 9.81 16 575542 109 110013632
Pulmonary arterial hypertension 35.86 9.81 72 575486 32496 109981245
Fusarium infection 35.76 9.81 57 575501 2714 110011027
Lung abscess 35.74 9.81 80 575478 4932 110008809
Cardiac arrest 35.70 9.81 766 574792 195987 109817754
Back pain 35.53 9.81 1573 573985 369423 109644318
Herpes simplex reactivation 35.53 9.81 41 575517 1427 110012314
Syringe issue 35.51 9.81 4 575554 9521 110004220
Product administration error 35.49 9.81 89 575469 37128 109976613
Mental status changes 35.40 9.81 241 575317 75881 109937860
Heart rate irregular 35.40 9.81 302 575256 33972 109979769
Urinary casts 35.30 9.81 39 575519 1293 110012448
Nephrolithiasis 35.26 9.81 201 575357 66011 109947730
American trypanosomiasis 35.18 9.81 28 575530 606 110013135
Blastomycosis 34.97 9.81 36 575522 1099 110012642
Shock haemorrhagic 34.71 9.81 252 575306 26995 109986746
Taste disorder 34.66 9.81 505 575053 64882 109948859
Bronchopleural fistula 34.39 9.81 32 575526 861 110012880
Blood thyroid stimulating hormone decreased 34.32 9.81 99 575459 7140 110006601
Pancreatitis 34.27 9.81 316 575242 93217 109920524
Thyroxine free increased 34.10 9.81 40 575518 1417 110012324
Haemodynamic instability 34.10 9.81 220 575338 22668 109991073
Parosmia 33.98 9.81 13 575545 13167 110000574
Tendonitis 33.86 9.81 52 575506 26031 109987710
Enterococcal bacteraemia 33.85 9.81 73 575485 4388 110009353
Chronic kidney disease 33.79 9.81 245 575313 76046 109937695
Plasmodium falciparum infection 33.57 9.81 17 575541 159 110013582
Blood glucose decreased 33.50 9.81 64 575494 29424 109984317
Human herpesvirus 6 infection reactivation 33.33 9.81 35 575523 1094 110012647
Viral infection 33.33 9.81 423 575135 52716 109961025
Product dispensing error 33.32 9.81 22 575536 16323 109997418
Dermatomyositis 33.31 9.81 72 575486 4334 110009407
Coronary artery dilatation 33.30 9.81 14 575544 81 110013660
Blood sodium decreased 33.25 9.81 96 575462 38223 109975518
Stress 33.19 9.81 369 575189 104979 109908762
Lung disorder 33.18 9.81 1197 574361 178850 109834891
Growth retardation 33.17 9.81 53 575505 2529 110011212
Osmotic demyelination syndrome 33.13 9.81 47 575511 2016 110011725
Muscle rigidity 33.06 9.81 46 575512 23985 109989756
Obliterative bronchiolitis 33.05 9.81 65 575493 3658 110010083
Rash erythematous 32.95 9.81 604 574954 81228 109932513
Drug dependence 32.88 9.81 141 575417 49879 109963862
Adenoviral hepatitis 32.83 9.81 33 575525 979 110012762
Rhinovirus infection 32.82 9.81 135 575423 11654 110002087
Liver injury 32.82 9.81 1020 574538 149393 109864348
Meningitis fungal 32.78 9.81 21 575537 318 110013423
Affect lability 32.76 9.81 187 575371 18450 109995291
Atrioventricular block 32.70 9.81 24 575534 16853 109996888
Balance disorder 32.61 9.81 419 575139 116141 109897600
Nasopharyngitis 32.56 9.81 2428 573130 391933 109621808
Thymus hypoplasia 32.52 9.81 42 575516 1645 110012096
Product complaint 32.50 9.81 16 575542 13956 109999785
Urobilinogen urine increased 32.43 9.81 27 575531 624 110013117
Bacillus infection 32.40 9.81 41 575517 1573 110012168
Hypocalcaemia 32.40 9.81 203 575355 65163 109948578
Hepatic cancer 32.29 9.81 9 575549 11147 110002594
Fungal endocarditis 32.28 9.81 30 575528 806 110012935
Proteus infection 32.22 9.81 55 575503 2773 110010968
Hiatus hernia 32.17 9.81 59 575499 27547 109986194
Complications of transplant surgery 32.11 9.81 29 575529 750 110012991
Jaundice cholestatic 32.10 9.81 18 575540 14590 109999151
Cytomegalovirus hepatitis 32.10 9.81 31 575527 875 110012866
Abdominal infection 32.06 9.81 74 575484 4657 110009084
Ventricular fibrillation 31.97 9.81 109 575449 41204 109972537
Peritonitis 31.95 9.81 284 575274 32323 109981418
Contraindicated product administered 31.92 9.81 1016 574542 247251 109766490
Central nervous system lymphoma 31.83 9.81 57 575501 2987 110010754
Encephalitis autoimmune 31.81 9.81 62 575496 3466 110010275
Trichodysplasia spinulosa 31.81 9.81 33 575525 1017 110012724
Band neutrophil percentage increased 31.76 9.81 22 575536 382 110013359
Familial periodic paralysis 31.68 9.81 21 575537 338 110013403
Swelling face 31.67 9.81 317 575241 92004 109921737
Renal impairment 31.65 9.81 1240 574318 187205 109826536
Disseminated varicella zoster vaccine virus infection 31.57 9.81 16 575542 150 110013591
Treatment noncompliance 31.55 9.81 236 575322 72754 109940987
Eye pruritus 31.55 9.81 78 575480 32697 109981044
Metastases to bone 31.52 9.81 73 575485 31299 109982442
Pseudomonal bacteraemia 31.43 9.81 70 575488 4301 110009440
Cells in urine 31.29 9.81 17 575541 186 110013555
Serratia infection 31.28 9.81 48 575510 2211 110011530
Appendicitis 31.28 9.81 63 575495 28401 109985340
Diabetes mellitus 31.23 9.81 707 574851 98674 109915067
Empyema 31.22 9.81 81 575477 5489 110008252
Liver abscess 31.22 9.81 100 575458 7639 110006102
Aplasia 31.10 9.81 101 575457 7772 110005969
Alternaria infection 31.01 9.81 32 575526 980 110012761
Histoplasmosis disseminated 30.96 9.81 65 575493 3834 110009907
Serum ferritin increased 30.91 9.81 133 575425 11714 110002027
CSF oligoclonal band present 30.90 9.81 23 575535 449 110013292
Urine leukocyte esterase 30.90 9.81 17 575541 191 110013550
Pneumothorax 30.89 9.81 300 575258 34985 109978756
Hypoproteinaemia 30.84 9.81 84 575474 5861 110007880
Idiopathic pneumonia syndrome 30.77 9.81 30 575528 857 110012884
Reticulocytosis 30.76 9.81 26 575532 614 110013127
Alcohol poisoning 30.75 9.81 5 575553 9015 110004726
Vesicoureteric reflux 30.67 9.81 17 575541 194 110013547
Kaposi's sarcoma 30.66 9.81 27 575531 675 110013066
Respiratory symptom 30.62 9.81 20 575538 14925 109998816
Wheezing 30.58 9.81 1054 574504 254176 109759565
Laryngeal stenosis 30.45 9.81 37 575521 1361 110012380
Human ehrlichiosis 30.23 9.81 27 575531 688 110013053
Oral pain 30.21 9.81 97 575461 37347 109976394
Cardiac murmur 30.18 9.81 51 575507 24577 109989164
Intestine transplant rejection 30.16 9.81 14 575544 106 110013635
Stomatitis 30.10 9.81 1126 574432 269116 109744625
Hepatic steatosis 30.08 9.81 141 575417 48690 109965051
Oliguria 30.08 9.81 183 575375 18474 109995267
Lactic acidosis 30.07 9.81 323 575235 92488 109921253
Hepatic infarction 30.02 9.81 31 575527 950 110012791
Pneumoperitoneum 30.00 9.81 65 575493 3919 110009822
Urinary tract candidiasis 29.88 9.81 34 575524 1165 110012576
Lymphoid tissue hypoplasia 29.85 9.81 40 575518 1625 110012116
SARS-CoV-2 viraemia 29.83 9.81 15 575543 138 110013603
Disseminated strongyloidiasis 29.80 9.81 25 575533 584 110013157
Coma scale abnormal 29.77 9.81 7 575551 9719 110004022
Scleroderma renal crisis 29.76 9.81 30 575528 893 110012848
Laboratory test abnormal 29.75 9.81 123 575435 43956 109969785
Injection site induration 29.72 9.81 11 575547 11372 110002369
Hypomagnesaemia 29.66 9.81 188 575370 60182 109953559
Urinary tract infection bacterial 29.65 9.81 101 575457 7966 110005775
Lung transplant rejection 29.56 9.81 43 575515 1888 110011853
Engraftment syndrome 29.54 9.81 43 575515 1889 110011852
Irritability 29.48 9.81 138 575420 47671 109966070
Sudden death 29.45 9.81 51 575507 24344 109989397
Impaired work ability 29.44 9.81 58 575500 26361 109987380
Human herpesvirus 6 encephalitis 29.43 9.81 32 575526 1042 110012699
Status epilepticus 29.42 9.81 272 575286 31299 109982442
Drug tolerance decreased 29.38 9.81 62 575496 27478 109986263
Incision site pain 29.38 9.81 56 575502 3079 110010662
Herpes zoster meningoencephalitis 29.33 9.81 32 575526 1046 110012695
Haemoglobin urine 29.29 9.81 15 575543 144 110013597
Passenger lymphocyte syndrome 29.22 9.81 16 575542 178 110013563
Subcutaneous drug absorption impaired 29.13 9.81 97 575461 7562 110006179
Periumbilical abscess 29.03 9.81 19 575539 299 110013442
Melaena 28.93 9.81 224 575334 68533 109945208
Fracture 28.87 9.81 53 575505 24735 109989006
Respiratory tract infection fungal 28.77 9.81 35 575523 1289 110012452
No adverse event 28.69 9.81 542 575016 73297 109940444
Monkeypox 28.59 9.81 20 575538 353 110013388
Monocyte count increased 28.58 9.81 141 575417 13152 110000589
Cystitis 28.57 9.81 493 575065 65543 109948198
Thirst 28.44 9.81 43 575515 21664 109992077
Acute disseminated encephalomyelitis 28.26 9.81 21 575537 409 110013332
Infusion site reaction 28.23 9.81 173 575385 17509 109996232
Sputum discoloured 28.10 9.81 65 575493 27880 109985861
Terminal ileitis 27.99 9.81 39 575519 1645 110012096
Meningoencephalitis viral 27.98 9.81 23 575535 522 110013219
Nasal polyps 27.96 9.81 17 575541 13183 110000558
Faecaloma 27.86 9.81 22 575536 14886 109998855
Sleep disorder due to a general medical condition 27.86 9.81 158 575400 51954 109961787
Exposure via skin contact 27.75 9.81 17 575541 13130 110000611
Alveolar proteinosis 27.69 9.81 37 575521 1499 110012242
Atypical haemolytic uraemic syndrome 27.61 9.81 37 575521 1503 110012238
Band sensation 27.60 9.81 31 575527 1047 110012694
Electrocardiogram abnormal 27.60 9.81 34 575524 18675 109995066
Anti-neutrophil cytoplasmic antibody positive vasculitis 27.56 9.81 76 575482 5341 110008400
Hepatic artery thrombosis 27.51 9.81 20 575538 376 110013365
Agitation 27.49 9.81 418 575140 112633 109901108
Transfusion 27.46 9.81 57 575501 25415 109988326
Angina unstable 27.39 9.81 27 575531 16405 109997336
Treatment failure 27.28 9.81 1732 573826 275502 109738239
Granulocyte count increased 27.27 9.81 42 575516 1941 110011800
Lip pruritus 27.20 9.81 34 575524 1288 110012453
Rash 27.13 9.81 3802 571756 817162 109196579
Bronchial anastomosis complication 27.09 9.81 13 575545 107 110013634
Microscopic polyangiitis 27.07 9.81 22 575536 491 110013250
Escherichia urinary tract infection 27.00 9.81 160 575398 16002 109997739
Adenoviral haemorrhagic cystitis 26.98 9.81 25 575533 669 110013072
Monocyte count decreased 26.94 9.81 61 575497 3790 110009951
Aplasia pure red cell 26.92 9.81 110 575448 9468 110004273
Adverse event 26.91 9.81 401 575157 108408 109905333
Inferior vena cava stenosis 26.88 9.81 13 575545 109 110013632
Maternal exposure during pregnancy 26.87 9.81 1602 573956 253281 109760460
Herpes simplex oesophagitis 26.84 9.81 21 575537 443 110013298
Incorrect route of product administration 26.81 9.81 209 575349 63852 109949889
Exposure during pregnancy 26.79 9.81 1096 574462 166328 109847413
Bundle branch block left 26.74 9.81 17 575541 12871 110000870
Visceral leishmaniasis 26.73 9.81 39 575519 1717 110012024
Candida pneumonia 26.72 9.81 30 575528 1013 110012728
Central nervous system lesion 26.65 9.81 155 575403 15398 109998343
Viral sepsis 26.55 9.81 16 575542 216 110013525
Road traffic accident 26.49 9.81 396 575162 107002 109906739
Citrobacter infection 26.40 9.81 34 575524 1328 110012413
Blood loss anaemia 26.34 9.81 33 575525 17992 109995749
Partial seizures 26.29 9.81 123 575435 11226 110002515
Blood beta-D-glucan increased 26.26 9.81 26 575532 757 110012984
Pancreas transplant rejection 26.15 9.81 19 575539 357 110013384
Hyperphosphataemia 26.08 9.81 28 575530 16353 109997388
Oropharyngeal pain 26.07 9.81 904 574654 134372 109879369
Tuberculosis 25.96 9.81 170 575388 17604 109996137
Meningitis aseptic 25.90 9.81 111 575447 9759 110003982
Knee arthroplasty 25.75 9.81 215 575343 64733 109949008
Delusion 25.74 9.81 53 575505 23702 109990039
Venoocclusive liver disease 25.70 9.81 151 575407 15056 109998685
Ageusia 25.66 9.81 39 575519 19606 109994135
Cardiac infection 25.63 9.81 24 575534 651 110013090
Breath sounds abnormal 25.61 9.81 59 575499 25345 109988396
Limbic encephalitis 25.57 9.81 26 575532 782 110012959
Pruritus 25.55 9.81 2643 572915 578917 109434824
Pneumocephalus 25.53 9.81 21 575537 477 110013264
Second primary malignancy 25.45 9.81 34 575524 18034 109995707
Tularaemia 25.45 9.81 15 575543 194 110013547
Carotid artery occlusion 25.39 9.81 9 575549 9556 110004185
Enterovirus infection 25.37 9.81 49 575509 2721 110011020
Eosinophil percentage increased 25.35 9.81 36 575522 1546 110012195
Femur fracture 25.33 9.81 132 575426 44337 109969404
Natural killer-cell leukaemia 25.29 9.81 12 575546 96 110013645
Sideroblastic anaemia 25.28 9.81 20 575538 429 110013312
Infectious pleural effusion 25.26 9.81 69 575489 4822 110008919
Tricuspid valve incompetence 25.25 9.81 54 575504 23819 109989922
Liver function test abnormal 25.24 9.81 233 575325 68717 109945024
Hepatocellular injury 25.24 9.81 387 575171 50255 109963486
Restlessness 25.23 9.81 180 575378 56079 109957662
Uterine perforation 25.18 9.81 3 575555 6837 110006904
pH urine increased 25.12 9.81 20 575538 433 110013308
Cellulitis 25.12 9.81 483 575075 125533 109888208
Acute respiratory failure 25.10 9.81 540 575018 74720 109939021
Angiosarcoma 25.08 9.81 22 575536 547 110013194
Bradypnoea 24.99 9.81 7 575551 8642 110005099
Aspergillosis oral 24.98 9.81 10 575548 50 110013691
Staphylococcal mediastinitis 24.98 9.81 10 575548 50 110013691
Venous thrombosis 24.96 9.81 99 575459 8406 110005335
Klebsiella sepsis 24.95 9.81 62 575496 4091 110009650
Enteritis 24.88 9.81 178 575380 18978 109994763
Dysstasia 24.87 9.81 88 575470 32898 109980843
Renal vein thrombosis 24.87 9.81 30 575528 1095 110012646
Smear cervix abnormal 24.87 9.81 48 575510 2664 110011077
Interstitial lung disease 24.86 9.81 923 574635 138411 109875330
Pyelonephritis 24.78 9.81 220 575338 25030 109988711
Coronavirus infection 24.78 9.81 107 575451 9438 110004303
Graft complication 24.72 9.81 30 575528 1102 110012639
Aspiration 24.70 9.81 79 575479 30454 109983287
Hypertensive encephalopathy 24.69 9.81 31 575527 1180 110012561
Peripheral vascular disorder 24.67 9.81 7 575551 8569 110005172
Vaginal haemorrhage 24.67 9.81 59 575499 25015 109988726
Blindness cortical 24.66 9.81 30 575528 1105 110012636
Motor dysfunction 24.66 9.81 214 575344 24192 109989549
Faeces discoloured 24.65 9.81 92 575466 33856 109979885
JC polyomavirus test positive 24.60 9.81 44 575514 2303 110011438
Urine bilirubin decreased 24.59 9.81 13 575545 134 110013607
Gastrointestinal fungal infection 24.53 9.81 25 575533 754 110012987
Cardiogenic shock 24.50 9.81 186 575372 57152 109956589
Cardiovascular disorder 24.48 9.81 51 575507 22709 109991032
Band neutrophil count increased 24.46 9.81 24 575534 691 110013050
Grip strength decreased 24.46 9.81 568 574990 79606 109934135
Mitral valve incompetence 24.41 9.81 90 575468 33239 109980502
Blood pressure systolic decreased 24.37 9.81 136 575422 13305 110000436
Splenic embolism 24.36 9.81 15 575543 211 110013530
Mycoplasma test positive 24.32 9.81 16 575542 254 110013487
Malacoplakia vesicae 24.31 9.81 11 575547 78 110013663
Muscle spasticity 24.30 9.81 290 575268 35625 109978116
Disturbance in attention 24.23 9.81 206 575352 61789 109951952
Disseminated toxoplasmosis 24.21 9.81 20 575538 457 110013284
Spinal cord abscess 24.20 9.81 23 575535 636 110013105
Splenic infection viral 24.07 9.81 9 575549 36 110013705
Sensitivity to weather change 24.07 9.81 11 575547 10017 110003724
Epstein-Barr virus test positive 23.99 9.81 32 575526 1294 110012447
Nocturia 23.90 9.81 32 575526 16958 109996783
Pneumonia aspiration 23.85 9.81 289 575269 80944 109932797
Aphthous ulcer 23.85 9.81 190 575368 20946 109992795
Osteoporosis 23.75 9.81 608 574950 86544 109927197
Myelitis 23.72 9.81 52 575506 3161 110010580
Normal newborn 23.71 9.81 195 575363 21701 109992040
Pruritus genital 23.67 9.81 3 575555 6519 110007222
Facet joint syndrome 23.67 9.81 666 574892 96162 109917579
Orchitis 23.62 9.81 38 575520 1824 110011917
Atypical mycobacterial pneumonia 23.60 9.81 17 575541 315 110013426
Lymphocele 23.48 9.81 38 575520 1833 110011908
Microsporidia infection 23.43 9.81 33 575525 1406 110012335
Injection site discolouration 23.43 9.81 9 575549 9094 110004647
Hypocomplementaemia 23.37 9.81 17 575541 320 110013421
Listeria encephalitis 23.32 9.81 17 575541 321 110013420
Type 2 diabetes mellitus 23.27 9.81 1137 574421 176095 109837646
Body height decreased 23.23 9.81 13 575545 10550 110003191
Disseminated cytomegaloviral infection 23.22 9.81 22 575536 606 110013135
Shock 23.16 9.81 400 575158 53188 109960553
Hip fracture 23.16 9.81 99 575459 35052 109978689
Muscle twitching 23.15 9.81 79 575479 29856 109983885
Wrong technique in device usage process 23.14 9.81 4 575554 6897 110006844
Drug screen positive 23.14 9.81 3 575555 6407 110007334
Arthralgia 23.08 9.81 3634 571924 775998 109237743
Mean cell haemoglobin increased 23.04 9.81 73 575485 5544 110008197
Hallucination, auditory 23.00 9.81 66 575492 26331 109987410
Metastases to central nervous system 23.00 9.81 53 575505 22764 109990977
Anxiety 22.95 9.81 1517 574041 343561 109670180
Intracranial infection 22.88 9.81 17 575541 331 110013410
Emphysematous pyelonephritis 22.82 9.81 21 575537 557 110013184
Large intestine polyp 22.80 9.81 27 575531 15090 109998651
Chronic graft versus host disease in liver 22.73 9.81 26 575532 896 110012845
Encephalitis brain stem 22.71 9.81 17 575541 335 110013406
Rubella antibody positive 22.70 9.81 10 575548 66 110013675
Donor specific antibody present 22.67 9.81 18 575540 388 110013353
Superinfection bacterial 22.64 9.81 43 575515 2358 110011383
Pneumatosis 22.63 9.81 27 575531 974 110012767
Coronary artery aneurysm 22.61 9.81 13 575545 160 110013581
Haemorrhoids 22.57 9.81 102 575456 35570 109978171
Cervical plexus lesion 22.54 9.81 6 575552 4 110013737
Malacoplakia gastrointestinal 22.49 9.81 15 575543 244 110013497
Drug level below therapeutic 22.44 9.81 120 575438 11553 110002188
Body temperature increased 22.43 9.81 405 575153 54308 109959433
Colitis microscopic 22.34 9.81 22 575536 13372 110000369
Body temperature fluctuation 22.32 9.81 56 575502 3717 110010024
Complication of device insertion 22.32 9.81 9 575549 8829 110004912
Blood brain barrier defect 22.31 9.81 14 575544 204 110013537
Alveolitis 22.31 9.81 62 575496 4377 110009364
Autoimmune thyroiditis 22.30 9.81 79 575479 6355 110007386
Increased ventricular preload 22.22 9.81 8 575550 28 110013713
Pericarditis fungal 22.14 9.81 16 575542 298 110013443
Calcium ionised decreased 22.12 9.81 22 575536 644 110013097
Dry throat 22.05 9.81 101 575457 9137 110004604
Drug eruption 22.02 9.81 176 575382 53483 109960258
Hepatic necrosis 21.87 9.81 106 575452 9816 110003925
Hemianopia 21.84 9.81 47 575511 2821 110010920
Ecthyma 21.83 9.81 27 575531 1012 110012729
Groin pain 21.76 9.81 29 575529 15399 109998342
Magnetic resonance imaging abnormal 21.74 9.81 57 575501 3888 110009853
Non-consummation 21.71 9.81 9 575549 50 110013691
Product preparation error 21.70 9.81 15 575543 10864 110002877
Perforation 21.69 9.81 36 575522 1774 110011967
Atrial flutter 21.63 9.81 60 575498 24202 109989539
Nose deformity 21.58 9.81 15 575543 262 110013479
Anorectal ulcer 21.56 9.81 9 575549 51 110013690
Post procedural bile leak 21.55 9.81 18 575540 418 110013323
Breast cancer metastatic 21.53 9.81 16 575542 11165 110002576
Colitis ischaemic 21.53 9.81 37 575521 17713 109996028
Cytomegalovirus gastritis 21.52 9.81 22 575536 666 110013075
Blood potassium decreased 21.52 9.81 179 575379 53935 109959806
Blood creatine phosphokinase increased 21.45 9.81 260 575298 72817 109940924
Organising pneumonia 21.28 9.81 137 575421 14106 109999635
White blood cells urine 21.25 9.81 19 575539 485 110013256
Red blood cell count increased 21.18 9.81 65 575493 4853 110008888
Red blood cell schistocytes present 21.17 9.81 23 575535 748 110012993
Multiple fractures 21.15 9.81 10 575548 8930 110004811
Renal haemorrhage 21.12 9.81 43 575515 2482 110011259
Cytokine storm 21.11 9.81 32 575526 1458 110012283
Microangiopathic haemolytic anaemia 21.11 9.81 37 575521 1906 110011835
CSF protein increased 21.10 9.81 32 575526 1459 110012282
Diverticulum 21.08 9.81 30 575528 15496 109998245
Bordetella infection 21.08 9.81 14 575544 226 110013515
Abnormal behaviour 21.06 9.81 118 575440 38921 109974820
Fungal peritonitis 21.00 9.81 30 575528 1295 110012446
Burns second degree 21.00 9.81 7 575551 7726 110006015
Complications of transplanted liver 20.99 9.81 19 575539 493 110013248
Pancreatic carcinoma 20.93 9.81 28 575530 14844 109998897
Adverse reaction 20.93 9.81 241 575317 29353 109984388
Tension headache 20.92 9.81 12 575546 9606 110004135
Abdominal pain upper 20.87 9.81 1549 574009 347562 109666179
Sodium retention 20.77 9.81 14 575544 232 110013509
Rash vesicular 20.71 9.81 139 575419 14513 109999228
International normalised ratio abnormal 20.63 9.81 4 575554 6353 110007388
Sickle cell anaemia with crisis 20.63 9.81 12 575546 9533 110004208
Bronchopulmonary aspergillosis allergic 20.60 9.81 9 575549 8417 110005324
Lipaemic index score 20.43 9.81 11 575547 118 110013623
Varicella 20.43 9.81 54 575504 3701 110010040
Pustular psoriasis 20.41 9.81 131 575427 13474 110000267
Haemorrhagic stroke 20.40 9.81 25 575533 13764 109999977
Amnesia 20.40 9.81 406 575152 105002 109908739
Ankylosing spondylitis 20.38 9.81 31 575527 15581 109998160
Faciobrachial dystonic seizure 20.37 9.81 10 575548 87 110013654
Chromophobe renal cell carcinoma 20.35 9.81 9 575549 60 110013681
Drug hypersensitivity 20.30 9.81 2061 573497 452029 109561712
Factor XIII deficiency 20.27 9.81 10 575548 88 110013653
Liver function test increased 20.25 9.81 604 574954 87944 109925797
Thrombotic thrombocytopenic purpura 20.25 9.81 82 575476 7029 110006712
Extra dose administered 20.25 9.81 20 575538 12139 110001602
Bacterial vulvovaginitis 20.25 9.81 21 575537 647 110013094
Nephritis 20.19 9.81 74 575484 6052 110007689
Mitochondrial DNA mutation 20.18 9.81 18 575540 458 110013283
SARS-CoV-2 test positive 20.08 9.81 154 575404 16781 109996960
Monocytopenia 20.06 9.81 13 575545 201 110013540
Sense of oppression 20.04 9.81 33 575525 1615 110012126
Ketoacidosis 20.00 9.81 14 575544 10073 110003668
CSF measles antibody positive 19.98 9.81 9 575549 63 110013678
Infusion site extravasation 19.97 9.81 116 575442 11518 110002223
Thymoma 19.92 9.81 17 575541 407 110013334
Butterfly rash 19.89 9.81 38 575520 2093 110011648
Engraft failure 19.87 9.81 23 575535 803 110012938
Vision blurred 19.87 9.81 515 575043 128507 109885234
Viral cardiomyopathy 19.82 9.81 8 575550 41 110013700
Plasma cell myeloma recurrent 19.79 9.81 6 575552 7036 110006705
Tri-iodothyronine free increased 19.78 9.81 14 575544 252 110013489
Asphyxia 19.77 9.81 27 575531 14188 109999553
Double stranded DNA antibody positive 19.77 9.81 19 575539 533 110013208
Cervicitis 19.76 9.81 15 575543 302 110013439
Cerebral artery stenosis 19.75 9.81 24 575534 883 110012858
IgA nephropathy 19.73 9.81 48 575510 3125 110010616
Oral candidiasis 19.67 9.81 335 575223 44425 109969316
Poikiloderma 19.66 9.81 18 575540 474 110013267
Mycobacterial infection 19.60 9.81 59 575499 4358 110009383
Norovirus infection 19.52 9.81 40 575518 2319 110011422
Sexual dysfunction 19.49 9.81 10 575548 8520 110005221
Multiple allergies 19.48 9.81 21 575537 12242 110001499
Biliary anastomosis complication 19.42 9.81 12 575546 170 110013571
Pre-existing condition improved 19.39 9.81 5 575553 6521 110007220
Application site erythema 19.37 9.81 3 575555 5607 110008134
Clostridium difficile colitis 19.36 9.81 328 575230 43450 109970291
Scopulariopsis infection 19.36 9.81 12 575546 171 110013570
Orbital apex syndrome 19.35 9.81 10 575548 98 110013643
Panniculitis 19.34 9.81 32 575526 15550 109998191
Dengue fever 19.32 9.81 29 575529 1310 110012431
Urine oxalate increased 19.31 9.81 13 575545 215 110013526
Peptostreptococcus infection 19.30 9.81 12 575546 172 110013569
Bifidobacterium infection 19.26 9.81 10 575548 99 110013642
Angiocentric lymphoma 19.25 9.81 28 575530 1229 110012512
Atrial tachycardia 19.19 9.81 12 575546 9166 110004575
Acinetobacter sepsis 19.16 9.81 11 575547 135 110013606
Tracheobronchitis viral 19.13 9.81 7 575551 26 110013715
Intestinal ischaemia 19.12 9.81 147 575411 16032 109997709
Mean cell haemoglobin concentration increased 19.09 9.81 26 575532 1073 110012668
Coinfection 19.09 9.81 11 575547 136 110013605
Neutrophil count decreased 19.09 9.81 481 575077 120460 109893281
Mean cell haemoglobin concentration decreased 19.04 9.81 69 575489 5613 110008128
Leukocyturia 19.04 9.81 39 575519 2261 110011480
Cardiac operation 18.99 9.81 4 575554 5991 110007750
Aortic stenosis 18.98 9.81 24 575534 13035 110000706
Bladder cancer 18.98 9.81 49 575509 20243 109993498
Blood phosphorus increased 18.97 9.81 35 575523 16305 109997436
Atypical mycobacterial infection 18.95 9.81 43 575515 2675 110011066
B-lymphocyte count increased 18.95 9.81 11 575547 138 110013603
Cholecystectomy 18.91 9.81 17 575541 10792 110002949
Obsessive-compulsive disorder 18.90 9.81 7 575551 7234 110006507
Locked-in syndrome 18.82 9.81 24 575534 928 110012813
Bradyphrenia 18.72 9.81 20 575538 11708 110002033
Blood albumin increased 18.72 9.81 35 575523 1896 110011845
Morganella infection 18.67 9.81 29 575529 1350 110012391
Haemoglobin abnormal 18.65 9.81 12 575546 9026 110004715
Hypoacusis 18.65 9.81 107 575451 35084 109978657
Metabolic encephalopathy 18.64 9.81 18 575540 11042 110002699
Central obesity 18.63 9.81 36 575522 2000 110011741
Inflammation 18.59 9.81 1205 574353 192033 109821708
Movement disorder 18.59 9.81 112 575446 36292 109977449
Vertigo 18.55 9.81 329 575229 86541 109927200
Blood immunoglobulin A increased 18.54 9.81 31 575527 1537 110012204
B-cell lymphoma 18.42 9.81 80 575478 7074 110006667
Arteriovenous fistula 18.42 9.81 30 575528 1455 110012286
Neuropsychiatric lupus 18.41 9.81 13 575545 233 110013508
Priapism 18.38 9.81 4 575554 5857 110007884
Spinal operation 18.32 9.81 18 575540 10954 110002787
Cryptosporidiosis infection 18.30 9.81 26 575532 1117 110012624
Insurance issue 18.20 9.81 17 575541 10595 110003146
Wrong patient received product 18.20 9.81 6 575552 6668 110007073
Blood magnesium decreased 18.16 9.81 49 575509 19947 109993794
Dizziness postural 18.14 9.81 30 575528 14579 109999162
Mite allergy 18.12 9.81 4 575554 5799 110007942
Pyelonephritis acute 18.07 9.81 80 575478 7133 110006608
Arteriosclerosis 18.06 9.81 67 575491 24700 109989041
Immunoglobulin G4 related disease 18.04 9.81 16 575542 404 110013337
Pyomyositis 18.01 9.81 21 575537 739 110013002
Birdshot chorioretinopathy 17.98 9.81 9 575549 82 110013659
Cestode infection 17.94 9.81 14 575544 294 110013447
Gout 17.89 9.81 114 575444 36452 109977289
Tracheobronchitis 17.87 9.81 42 575516 2674 110011067
Lichen sclerosus 17.87 9.81 26 575532 1142 110012599
Herpes simplex encephalitis 17.82 9.81 22 575536 823 110012918
Haemostasis 17.80 9.81 18 575540 538 110013203
Meningomyelitis herpes 17.79 9.81 9 575549 84 110013657
Complications of transplanted lung 17.77 9.81 20 575538 677 110013064
Encephalopathy 17.76 9.81 550 575008 80505 109933236
Abortion spontaneous 17.76 9.81 105 575453 34177 109979564
Dysmenorrhoea 17.73 9.81 50 575508 3560 110010181
Renal artery stenosis 17.71 9.81 51 575507 3675 110010066
Post cholecystectomy syndrome 17.67 9.81 22 575536 830 110012911
Nodular regenerative hyperplasia 17.64 9.81 31 575527 1600 110012141
Pelvic fracture 17.63 9.81 29 575529 14125 109999616
Intestinal ulcer 17.60 9.81 39 575519 2388 110011353
Foot operation 17.58 9.81 8 575550 7305 110006436
Coccidioidomycosis 17.56 9.81 31 575527 1606 110012135
Depression 17.55 9.81 1417 574141 315918 109697823
Kidney rupture 17.54 9.81 13 575545 252 110013489
Red blood cell sedimentation rate 17.53 9.81 3 575555 5211 110008530
Pharyngeal dyskinesia 17.53 9.81 8 575550 58 110013683
Renal necrosis 17.51 9.81 14 575544 305 110013436
Eosinophil percentage decreased 17.44 9.81 15 575543 363 110013378
Ultrasound ovary abnormal 17.43 9.81 9 575549 88 110013653
Fungal sepsis 17.43 9.81 37 575521 2200 110011541
Pneumonia adenoviral 17.41 9.81 19 575539 621 110013120
Graft infection 17.40 9.81 21 575537 767 110012974
Peritoneal candidiasis 17.36 9.81 6 575552 18 110013723
Clostridium colitis 17.36 9.81 47 575511 3268 110010473
Femoral neck fracture 17.35 9.81 24 575534 12543 110001198
Mental impairment 17.34 9.81 60 575498 22579 109991162
Duodenal perforation 17.33 9.81 42 575516 2728 110011013
Rhesus antigen positive 17.33 9.81 10 575548 124 110013617
Hairy cell leukaemia 17.32 9.81 11 575547 164 110013577
Cystitis viral 17.25 9.81 29 575529 1444 110012297
Bronchiectasis 17.24 9.81 115 575443 36378 109977363
Expired product administered 17.23 9.81 11 575547 8309 110005432
Device occlusion 17.21 9.81 33 575525 15152 109998589
Injection site extravasation 17.20 9.81 101 575457 10068 110003673
Meningitis listeria 17.18 9.81 27 575531 1270 110012471
Hepatic artery aneurysm 17.17 9.81 9 575549 91 110013650
Torulopsis infection 17.17 9.81 7 575551 37 110013704
Device failure 17.15 9.81 8 575550 7199 110006542
Trichosporon infection 17.13 9.81 27 575531 1273 110012468
Anti-thyroid antibody positive 17.13 9.81 18 575540 563 110013178
Serratia sepsis 16.95 9.81 13 575545 266 110013475
Hypercalcaemia 16.93 9.81 158 575400 46499 109967242
Joint tuberculosis 16.91 9.81 12 575546 217 110013524
Acarodermatitis 16.88 9.81 34 575524 1947 110011794
Seronegative arthritis 16.86 9.81 122 575436 13055 110000686
Chills 16.84 9.81 1180 574378 189400 109824341
Ejection fraction decreased 16.81 9.81 134 575424 40746 109972995
Chorioretinitis 16.76 9.81 28 575530 1387 110012354
Pulmonary cavitation 16.76 9.81 36 575522 2158 110011583
Latent autoimmune diabetes in adults 16.76 9.81 11 575547 174 110013567
Therapeutic product effect decreased 16.75 9.81 1071 574487 243245 109770496
Prescription drug used without a prescription 16.74 9.81 4 575554 5492 110008249
Wound evisceration 16.72 9.81 10 575548 133 110013608
Hypersomnia 16.72 9.81 82 575476 27979 109985762
Coronary arterial stent insertion 16.70 9.81 5 575553 5910 110007831
Paranoia 16.66 9.81 60 575498 22314 109991427
Paraparesis 16.63 9.81 57 575501 4509 110009232
Bacterial pyelonephritis 16.63 9.81 21 575537 804 110012937
Histology abnormal 16.61 9.81 15 575543 388 110013353
Necrosis 16.60 9.81 109 575449 11297 110002444
Cardiac pacemaker insertion 16.60 9.81 6 575552 6295 110007446
Gastrointestinal viral infection 16.60 9.81 31 575527 1678 110012063
Cytomegalovirus gastrointestinal ulcer 16.60 9.81 10 575548 135 110013606
Acute oesophageal mucosal lesion 16.60 9.81 11 575547 177 110013564
Haemorrhagic varicella syndrome 16.58 9.81 5 575553 8 110013733
Bradykinesia 16.56 9.81 19 575539 10769 110002972
Myelocyte percentage increased 16.54 9.81 12 575546 225 110013516
Sinusitis 16.53 9.81 1324 574234 295364 109718377
Meningitis 16.53 9.81 111 575447 11591 110002150
Small intestinal obstruction 16.51 9.81 99 575459 32114 109981627
Premenstrual syndrome 16.51 9.81 18 575540 588 110013153
Complications of transplanted heart 16.44 9.81 16 575542 456 110013285
Meningoencephalitis bacterial 16.44 9.81 16 575542 456 110013285
Delayed engraftment 16.42 9.81 13 575545 279 110013462
Hyperlipidaemia 16.42 9.81 114 575444 35734 109978007
Encephalomyelitis 16.41 9.81 14 575544 335 110013406
Post-traumatic stress disorder 16.41 9.81 73 575485 6523 110007218
T-cell type acute leukaemia 16.37 9.81 14 575544 336 110013405
Eye infection toxoplasmal 16.37 9.81 20 575538 740 110013001
Adrenal atrophy 16.35 9.81 8 575550 69 110013672
Central nervous system lupus 16.33 9.81 27 575531 1326 110012415
Hydronephrosis 16.31 9.81 172 575386 20493 109993248
Leukocytosis 16.31 9.81 381 575177 53447 109960294
Klebsiella test positive 16.29 9.81 38 575520 2408 110011333
Episcleritis 16.28 9.81 26 575532 1240 110012501
Skin test positive 16.27 9.81 28 575530 1421 110012320
Euglycaemic diabetic ketoacidosis 16.24 9.81 22 575536 11601 110002140
Alcohol abuse 16.22 9.81 3 575555 4926 110008815
Dermatitis 16.21 9.81 82 575476 27755 109985986
Complication associated with device 16.19 9.81 52 575506 20021 109993720
Stridor 16.17 9.81 75 575483 6820 110006921
Peliosis hepatis 16.13 9.81 11 575547 186 110013555
Cerebral venous sinus thrombosis 16.13 9.81 42 575516 2853 110010888
Retinal detachment 16.11 9.81 106 575452 10994 110002747
Sinus node dysfunction 16.11 9.81 14 575544 9033 110004708
Accident 16.05 9.81 20 575538 10932 110002809
Eye infection fungal 16.05 9.81 18 575540 607 110013134
Conjunctivitis allergic 16.02 9.81 8 575550 6923 110006818
Urinary tract infection enterococcal 16.01 9.81 49 575509 3653 110010088
Capillary leak syndrome 15.94 9.81 59 575499 4849 110008892
Injection site discomfort 15.93 9.81 8 575550 6899 110006842
Cytomegalovirus duodenitis 15.92 9.81 10 575548 146 110013595
Epididymitis 15.90 9.81 38 575520 2446 110011295
Malignant catatonia 15.89 9.81 19 575539 687 110013054
Sinus disorder 15.88 9.81 249 575309 32479 109981262
Biloma 15.88 9.81 12 575546 240 110013501
Lower respiratory tract congestion 15.86 9.81 58 575500 4738 110009003
Scleritis 15.83 9.81 63 575495 5357 110008384
Eschar 15.83 9.81 28 575530 1453 110012288
Optic perineuritis 15.79 9.81 7 575551 47 110013694
Urethral polyp 15.78 9.81 8 575550 75 110013666
Parainfluenzae virus infection 15.73 9.81 75 575483 6899 110006842
Disseminated coccidioidomycosis 15.71 9.81 12 575546 244 110013497
Erosive duodenitis 15.70 9.81 36 575522 2255 110011486
Fungal test positive 15.68 9.81 24 575534 1103 110012638
Quadriparesis 15.63 9.81 57 575501 4650 110009091
Arterial intramural haematoma 15.63 9.81 12 575546 246 110013495
Product dose omission in error 15.62 9.81 66 575492 23446 109990295
Shock symptom 15.61 9.81 16 575542 486 110013255
Haemorrhage 15.60 9.81 429 575129 106263 109907478
Aspergilloma 15.57 9.81 20 575538 779 110012962
Diverticulum intestinal 15.56 9.81 23 575535 11696 110002045
Toxic epidermal necrolysis 15.53 9.81 396 575162 56331 109957410
Intentional dose omission 15.52 9.81 53 575505 20027 109993714
Injection site inflammation 15.49 9.81 3 575555 4768 110008973
Amoebiasis 15.46 9.81 10 575548 154 110013587
Thunderclap headache 15.45 9.81 17 575541 561 110013180
Gastroduodenal ulcer 15.42 9.81 22 575536 949 110012792
Nosocomial infection 15.41 9.81 44 575514 3155 110010586
Atrioventricular block second degree 15.38 9.81 12 575546 8169 110005572
Encephalitis fungal 15.30 9.81 12 575546 254 110013487
Tumefactive multiple sclerosis 15.30 9.81 10 575548 157 110013584
Peripheral artery aneurysm 15.27 9.81 16 575542 499 110013242
Antinuclear antibody 15.25 9.81 15 575543 433 110013308
Interleukin level increased 15.24 9.81 29 575529 1592 110012149
Campylobacter gastroenteritis 15.14 9.81 32 575526 1897 110011844
Encephalitis viral 15.11 9.81 42 575516 2965 110010776
Papilloma viral infection 15.11 9.81 34 575524 2104 110011637
Cytomegalovirus nephritis 15.08 9.81 10 575548 161 110013580
ADAMTS13 activity decreased 15.07 9.81 13 575545 316 110013425
Breast cancer stage III 15.06 9.81 528 575030 78589 109935152
Autoimmune hepatitis 15.06 9.81 130 575428 14674 109999067
Herpes simplex viraemia 15.05 9.81 18 575540 651 110013090
Gastritis fungal 15.03 9.81 13 575545 317 110013424
Tearfulness 15.01 9.81 10 575548 7385 110006356
Vein rupture 15.01 9.81 38 575520 2537 110011204
Lumbosacral plexus lesion 14.98 9.81 5 575553 13 110013728
Haemophilus infection 14.96 9.81 40 575518 2760 110010981
Paraplegia 14.96 9.81 68 575490 6132 110007609
Glomerular filtration rate increased 14.95 9.81 32 575526 1913 110011828
Meningitis bacterial 14.95 9.81 43 575515 3096 110010645
Myelosuppression 14.94 9.81 375 575183 93965 109919776
Reticulocytopenia 14.93 9.81 13 575545 320 110013421
Aspartate aminotransferase increased 14.91 9.81 680 574878 159256 109854485
Monocyte percentage decreased 14.90 9.81 13 575545 321 110013420
Suspected COVID-19 14.89 9.81 46 575512 3447 110010294
Ischaemic stroke 14.86 9.81 140 575418 41123 109972618
Myelopathy 14.86 9.81 63 575495 5513 110008228
Metastases to salivary gland 14.84 9.81 8 575550 86 110013655
Nephrogenic systemic fibrosis 14.83 9.81 5 575553 5478 110008263
Japanese spotted fever 14.83 9.81 6 575552 31 110013710
Upper gastrointestinal haemorrhage 14.79 9.81 178 575380 49918 109963823
Eye haemorrhage 14.78 9.81 24 575534 11750 110001991
Catarrh 14.78 9.81 10 575548 7325 110006416
Cutaneous malacoplakia 14.77 9.81 10 575548 167 110013574
Fungal abscess central nervous system 14.73 9.81 11 575547 216 110013525
Hepatitis C 14.72 9.81 114 575444 12459 110001282
Eye luxation 14.72 9.81 5 575553 14 110013727
Overlap syndrome 14.70 9.81 89 575469 8970 110004771
Rib fracture 14.69 9.81 109 575449 33661 109980080
Sleep apnoea syndrome 14.66 9.81 137 575421 40310 109973431
Muir-Torre syndrome 14.65 9.81 7 575551 57 110013684
Lower limb fracture 14.65 9.81 290 575268 75058 109938683
Vaccination failure 14.62 9.81 37 575521 2469 110011272
Wound infection bacterial 14.62 9.81 22 575536 996 110012745
Immunoglobulins decreased 14.61 9.81 36 575522 2363 110011378
Middle insomnia 14.60 9.81 56 575502 20446 109993295
Diaphragmatic injury 14.59 9.81 9 575549 127 110013614
Skin discolouration 14.58 9.81 174 575384 48872 109964869
Tuberculosis gastrointestinal 14.57 9.81 17 575541 599 110013142
Renal disorder 14.54 9.81 176 575382 49303 109964438
Basal cell carcinoma 14.48 9.81 158 575400 45112 109968629
Hepatic cirrhosis 14.47 9.81 256 575302 67370 109946371
Mycobacterium kansasii infection 14.47 9.81 14 575544 396 110013345
Lupus myocarditis 14.46 9.81 8 575550 91 110013650
Sleep disorder 14.45 9.81 866 574692 197778 109815963
Temperature intolerance 14.45 9.81 123 575435 13827 109999914
Anaphylactoid reaction 14.39 9.81 72 575486 6754 110006987
Erythema infectiosum 14.34 9.81 11 575547 225 110013516
Varices oesophageal 14.32 9.81 10 575548 7205 110006536
Meningitis exserohilum 14.30 9.81 4 575554 4 110013737
Glomerulonephritis rapidly progressive 14.30 9.81 34 575524 2181 110011560
Acute myeloid leukaemia 14.29 9.81 128 575430 37982 109975759
Weight increased 14.28 9.81 2438 573120 417206 109596535
Steroid dependence 14.25 9.81 84 575474 8385 110005356
Cancer in remission 14.25 9.81 7 575551 61 110013680
Endocarditis bacterial 14.23 9.81 30 575528 1775 110011966
Mood altered 14.20 9.81 60 575498 21315 109992426
Feeding disorder 14.17 9.81 60 575498 21302 109992439
Thrombosis in device 14.16 9.81 5 575553 5322 110008419
Neutrophilic dermatosis 14.16 9.81 19 575539 773 110012968
Gastropleural fistula 14.15 9.81 7 575551 62 110013679
Meningitis staphylococcal 14.14 9.81 11 575547 230 110013511
Chromaturia 14.13 9.81 92 575466 29268 109984473
Anaphylactic reaction 14.11 9.81 729 574829 113571 109900170
Cognitive disorder 14.09 9.81 347 575211 87164 109926577
Leukoencephalopathy 14.08 9.81 89 575469 9106 110004635
Skin irritation 14.07 9.81 41 575517 16278 109997463
Intestinal intraepithelial lymphocytes increased 14.06 9.81 11 575547 232 110013509
Hypokinesia 14.06 9.81 62 575496 21764 109991977
Ear swelling 14.02 9.81 33 575525 2103 110011638
Hepatitis E 13.98 9.81 53 575505 4406 110009335
Gonococcal infection 13.96 9.81 7 575551 64 110013677
Mean cell haemoglobin decreased 13.96 9.81 74 575484 7100 110006641
Swollen joint count increased 13.95 9.81 330 575228 83331 109930410
Demodicidosis 13.94 9.81 11 575547 235 110013506
Hereditary angioedema 13.94 9.81 10 575548 7104 110006637
Hepatic function abnormal 13.93 9.81 583 574975 88712 109925029
Muscle strain 13.91 9.81 23 575535 11179 110002562
Angiosarcoma metastatic 13.89 9.81 10 575548 185 110013556
Diffuse large B-cell lymphoma stage III 13.88 9.81 8 575550 99 110013642
Embolic stroke 13.86 9.81 15 575543 8728 110005013
Propofol infusion syndrome 13.85 9.81 37 575521 2552 110011189
Astrovirus test positive 13.82 9.81 6 575552 38 110013703
Pulmonary air leakage 13.79 9.81 12 575546 295 110013446
Q fever 13.79 9.81 12 575546 295 110013446
Uraemic encephalopathy 13.79 9.81 19 575539 793 110012948
Pelvic pain 13.79 9.81 40 575518 15902 109997839
Panic attack 13.77 9.81 91 575467 28849 109984892
Creatinine urine decreased 13.75 9.81 13 575545 357 110013384
Oral bacterial infection 13.74 9.81 8 575550 101 110013640
Rhodococcus infection 13.73 9.81 15 575543 491 110013250
Alanine aminotransferase abnormal 13.73 9.81 17 575541 9317 110004424
Wound 13.71 9.81 1042 574516 233395 109780346
Brain herniation 13.70 9.81 86 575472 8777 110004964
Bundle branch block right 13.68 9.81 27 575531 12264 110001477
Hyperoxaluria 13.66 9.81 13 575545 360 110013381
Cryptococcal cutaneous infection 13.66 9.81 12 575546 299 110013442
Iron deficiency anaemia 13.66 9.81 102 575456 31457 109982284
Leishmaniasis 13.66 9.81 15 575543 494 110013247
Hepatic failure 13.65 9.81 461 575097 68278 109945463
Mydriasis 13.64 9.81 64 575494 22093 109991648
Rheumatoid factor increased 13.60 9.81 36 575522 2469 110011272
Ulcerative keratitis 13.60 9.81 55 575503 4711 110009030
Hyperferritinaemia 13.60 9.81 22 575536 1061 110012680
CD8 lymphocytes decreased 13.59 9.81 12 575546 301 110013440
Hypofibrinogenaemia 13.59 9.81 36 575522 2471 110011270
Tachypnoea 13.57 9.81 284 575274 39111 109974630
Human papilloma virus test positive 13.56 9.81 17 575541 646 110013095
Menstruation irregular 13.56 9.81 63 575495 5734 110008007
Ventricular tachycardia 13.53 9.81 181 575377 49828 109963913
Splenic abscess 13.50 9.81 21 575537 979 110012762
Libido decreased 13.50 9.81 7 575551 5928 110007813
Craniocerebral injury 13.49 9.81 7 575551 5927 110007814
Anger 13.48 9.81 52 575506 18955 109994786
Muscle abscess 13.47 9.81 26 575532 1443 110012298
Transient hypogammaglobulinaemia of infancy 13.44 9.81 6 575552 41 110013700
Cutaneous nocardiosis 13.43 9.81 12 575546 306 110013435
Blood catecholamines abnormal 13.42 9.81 4 575554 6 110013735
Myelocyte present 13.42 9.81 4 575554 6 110013735
Spondylitis 13.39 9.81 103 575455 11235 110002506
Diabetic ketoacidosis 13.37 9.81 147 575411 41911 109971830
Post procedural haemorrhage 13.36 9.81 39 575519 15473 109998268
Vessel puncture site bruise 13.35 9.81 15 575543 507 110013234
Hepatic artery occlusion 13.34 9.81 8 575550 107 110013634
Abscess 13.34 9.81 209 575349 27260 109986481
Chimerism 13.33 9.81 12 575546 309 110013432
Upper airway necrosis 13.32 9.81 6 575552 42 110013699
Cataract operation 13.29 9.81 7 575551 5876 110007865
Granulomatous liver disease 13.28 9.81 27 575531 1557 110012184
Dehiscence 13.27 9.81 18 575540 740 110013001
Rotavirus infection 13.27 9.81 20 575538 907 110012834
Post procedural urine leak 13.26 9.81 9 575549 151 110013590
Dyschromatopsia 13.23 9.81 24 575534 1270 110012471
Actinomycotic sepsis 13.23 9.81 10 575548 200 110013541
Genital herpes 13.22 9.81 36 575522 2511 110011230
Gynaecomastia 13.22 9.81 18 575540 9472 110004269
Urinoma 13.22 9.81 11 575547 254 110013487
Perineal ulceration 13.21 9.81 8 575550 109 110013632
Glomerulonephritis membranous 13.21 9.81 31 575527 1972 110011769
International normalised ratio decreased 13.20 9.81 14 575544 8222 110005519
General symptom 13.16 9.81 85 575473 8761 110004980
Arrhythmia 13.16 9.81 269 575289 69306 109944435
Tri-iodothyronine free decreased 13.14 9.81 14 575544 445 110013296
Adrenal insufficiency 13.14 9.81 301 575257 42089 109971652
Glomerulonephritis membranoproliferative 13.12 9.81 19 575539 831 110012910
Stent placement 13.12 9.81 11 575547 7223 110006518
Thyroid stimulating immunoglobulin 13.09 9.81 7 575551 74 110013667
Cryptitis 13.09 9.81 13 575545 380 110013361
Intravascular haemolysis 13.08 9.81 21 575537 1006 110012735
Bone marrow failure 13.07 9.81 394 575164 57454 109956287
Hypocholesterolaemia 13.02 9.81 67 575491 6354 110007387
Bronchiolitis obliterans syndrome 13.02 9.81 17 575541 673 110013068
Liver disorder 13.01 9.81 606 574952 141637 109872104
Subacute sclerosing panencephalitis 13.01 9.81 7 575551 75 110013666
Mediastinitis 13.01 9.81 25 575533 1383 110012358
Gastric haemorrhage 13.00 9.81 41 575517 15874 109997867
Aeromonas infection 13.00 9.81 15 575543 522 110013219
Colorectal cancer 12.99 9.81 17 575541 9097 110004644
Colon cancer 12.99 9.81 43 575515 16400 109997341
Incorrect drug administration rate 12.99 9.81 60 575498 5448 110008293
Injection site nodule 12.98 9.81 4 575554 4642 110009099
Bone infarction 12.97 9.81 16 575542 598 110013143
Neoplasm malignant 12.96 9.81 127 575431 37016 109976725
Thrombocytopenic purpura 12.93 9.81 40 575518 2999 110010742
Anticoagulation drug level above therapeutic 12.91 9.81 4 575554 4626 110009115
Therapy change 12.91 9.81 20 575538 9977 110003764
Abdominal compartment syndrome 12.90 9.81 30 575528 1897 110011844
Small intestinal perforation 12.89 9.81 51 575507 4325 110009416
Hyperplasia 12.87 9.81 26 575532 1492 110012249
Benign prostatic hyperplasia 12.86 9.81 50 575508 18184 109995557
Underdose 12.84 9.81 243 575315 63311 109950430
Infertility 12.83 9.81 18 575540 764 110012977
Magnesium deficiency 12.78 9.81 18 575540 767 110012974
Hepatic infection fungal 12.77 9.81 12 575546 327 110013414
Drooling 12.77 9.81 11 575547 7128 110006613
Hypertensive heart disease 12.77 9.81 4 575554 4592 110009149
Renal cyst infection 12.76 9.81 11 575547 267 110013474
Radiotherapy to brain 12.75 9.81 6 575552 47 110013694
Chronic lymphocytic leukaemia recurrent 12.75 9.81 21 575537 1028 110012713
Bruxism 12.75 9.81 5 575553 4989 110008752
Haemolysis 12.74 9.81 131 575427 15508 109998233
Mucosal ulceration 12.73 9.81 34 575524 2345 110011396
Application site pruritus 12.72 9.81 3 575555 4157 110009584
Osteogenesis imperfecta 12.71 9.81 18 575540 771 110012970
Neurosarcoidosis 12.70 9.81 14 575544 463 110013278
Left ventricular failure 12.69 9.81 25 575533 11364 110002377
Haptoglobin decreased 12.65 9.81 28 575530 1713 110012028
Breast abscess 12.65 9.81 28 575530 1713 110012028
Retinal scar 12.65 9.81 14 575544 465 110013276
Vitritis infective 12.65 9.81 6 575552 48 110013693
Bipolar disorder 12.63 9.81 17 575541 8990 110004751
Herpes simplex meningoencephalitis 12.62 9.81 7 575551 80 110013661
Ovarian fibroma 12.62 9.81 7 575551 80 110013661
Erythrosis 12.62 9.81 10 575548 215 110013526
Metabolic acidosis 12.62 9.81 409 575149 99335 109914406
Immune effector cell-associated neurotoxicity syndrome 12.61 9.81 125 575433 14657 109999084
Hypersensitivity 12.60 9.81 1877 573681 402121 109611620
Aspartate aminotransferase 12.60 9.81 20 575538 949 110012792
Bone lesion 12.58 9.81 11 575547 7076 110006665
Virologic failure 12.57 9.81 5 575553 4947 110008794
Endocrine toxicity 12.55 9.81 7 575551 81 110013660
Microangiopathy 12.54 9.81 39 575519 2933 110010808
Secondary adrenocortical insufficiency 12.52 9.81 51 575507 4383 110009358
Blood creatinine decreased 12.51 9.81 86 575472 9051 110004690
Joint range of motion decreased 12.50 9.81 764 574794 121068 109892673
Clonal haematopoiesis 12.48 9.81 9 575549 167 110013574
Breast cancer stage I 12.47 9.81 12 575546 7375 110006366
Central nervous system vasculitis 12.47 9.81 27 575531 1627 110012114
Epiglottic erythema 12.47 9.81 7 575551 82 110013659
Infective myositis 12.46 9.81 10 575548 219 110013522
Leukodystrophy 12.44 9.81 6 575552 50 110013691
Unmasking of previously unidentified disease 12.44 9.81 38 575520 2830 110010911
Conjunctival oedema 12.43 9.81 26 575532 1530 110012211
Skin cancer 12.39 9.81 49 575509 17735 109996006
Herpes oesophagitis 12.39 9.81 13 575545 406 110013335
Dermatitis acneiform 12.39 9.81 30 575528 12665 110001076
Disseminated trichosporonosis 12.39 9.81 10 575548 221 110013520
Hepatic encephalopathy 12.38 9.81 91 575467 28165 109985576
Pharyngeal disorder 12.38 9.81 37 575521 2722 110011019
Abdominal pain lower 12.38 9.81 129 575429 37154 109976587
Immunisation reaction 12.36 9.81 18 575540 791 110012950
Thyroid stimulating immunoglobulin increased 12.34 9.81 9 575549 170 110013571
Central nervous system abscess 12.34 9.81 6 575552 51 110013690
Cervical spinal cord paralysis 12.33 9.81 5 575553 26 110013715
Aortitis salmonella 12.33 9.81 5 575553 26 110013715
Urogenital disorder 12.33 9.81 7 575551 84 110013657
Glossodynia 12.32 9.81 991 574567 221013 109792728
Oropharyngeal discomfort 12.30 9.81 94 575464 10233 110003508
Acinetobacter test positive 12.26 9.81 11 575547 282 110013459
Perforation bile duct 12.26 9.81 7 575551 85 110013656
Femoral nerve palsy 12.26 9.81 7 575551 85 110013656
Polyneuropathy 12.23 9.81 107 575451 31905 109981836
Drug level decreased 12.21 9.81 149 575409 18399 109995342
Tumour haemorrhage 12.21 9.81 6 575552 5239 110008502
Internal haemorrhage 12.21 9.81 21 575537 10050 110003691
Administration site bruise 12.20 9.81 10 575548 226 110013515
Haemoperitoneum 12.19 9.81 58 575500 5330 110008411
Graft versus host disease in lung 12.19 9.81 23 575535 1255 110012486
Infected varicose vein 12.18 9.81 5 575553 27 110013714
Pulse pressure increased 12.17 9.81 9 575549 174 110013567
Myocarditis infectious 12.16 9.81 8 575550 127 110013614
Non-small cell lung cancer 12.15 9.81 14 575544 7921 110005820
Parathyroid hyperplasia 12.12 9.81 9 575549 175 110013566
Haemangioma-thrombocytopenia syndrome 12.10 9.81 4 575554 10 110013731
Posture abnormal 12.08 9.81 4 575554 4434 110009307
Moyamoya disease 12.06 9.81 8 575550 129 110013612
Amoebic dysentery 12.05 9.81 6 575552 54 110013687
Red blood cell elliptocytes present 12.04 9.81 9 575549 177 110013564
Exposure to SARS-CoV-2 12.03 9.81 38 575520 2881 110010860
Pallor 12.01 9.81 214 575344 56253 109957488
Urine bilirubin increased 12.00 9.81 8 575550 130 110013611
Hepatic enzyme 11.99 9.81 56 575502 5107 110008634
Tick-borne viral encephalitis 11.99 9.81 9 575549 178 110013563
Crying 11.98 9.81 81 575477 25547 109988194
Sleep disorder due to general medical condition, hypersomnia type 11.98 9.81 30 575528 1989 110011752
Enzyme level increased 11.98 9.81 14 575544 494 110013247
Dysphonia 11.97 9.81 302 575256 75627 109938114
Red cell distribution width decreased 11.96 9.81 32 575526 2209 110011532
Apnoea 11.96 9.81 34 575524 13605 110000136
Fibrin D dimer increased 11.94 9.81 90 575468 9755 110003986
Lymphocytic infiltration 11.92 9.81 30 575528 1995 110011746
Local anaesthetic systemic toxicity 11.91 9.81 7 575551 5530 110008211
Heliotrope rash 11.91 9.81 10 575548 234 110013507
Cutaneous B-cell lymphoma 11.90 9.81 8 575550 132 110013609
Marginal zone lymphoma 11.87 9.81 10 575548 235 110013506
Multisystem inflammatory syndrome in children 11.86 9.81 6 575552 56 110013685
Renal cancer 11.79 9.81 32 575526 13002 110000739
Diverticulum intestinal haemorrhagic 11.78 9.81 5 575553 4758 110008983
Retinitis 11.78 9.81 235 575323 32092 109981649
Bronchopneumopathy 11.78 9.81 19 575539 914 110012827
Paronychia 11.78 9.81 25 575533 11056 110002685
Enterococcal sepsis 11.76 9.81 41 575517 3271 110010470
Oculomotor study abnormal 11.74 9.81 5 575553 30 110013711
Product residue present 11.74 9.81 3 575555 3938 110009803
Gastroenteritis Escherichia coli 11.70 9.81 23 575535 1294 110012447
Cellulitis orbital 11.69 9.81 20 575538 1010 110012731
Inflammatory marker increased 11.69 9.81 121 575437 14348 109999393
Blood immunoglobulin E increased 11.68 9.81 13 575545 7469 110006272
Exophthalmos 11.67 9.81 32 575526 2241 110011500
Mycobacterium marinum infection 11.66 9.81 17 575541 748 110012993
Splenic necrosis 11.66 9.81 9 575549 186 110013555
Chronic graft versus host disease in skin 11.64 9.81 35 575523 2584 110011157
Haemorrhoidal haemorrhage 11.63 9.81 15 575543 8078 110005663
Haemorrhagic pneumonia 11.62 9.81 9 575549 187 110013554
Acute allograft nephropathy 11.59 9.81 6 575552 59 110013682
Product administration interrupted 11.57 9.81 26 575532 11266 110002475
Hydrocephalus 11.56 9.81 93 575465 10282 110003459
Systemic viral infection 11.54 9.81 8 575550 139 110013602
Myelitis transverse 11.54 9.81 33 575525 2368 110011373
Personality change 11.54 9.81 25 575533 10977 110002764
White coat hypertension 11.53 9.81 23 575535 1308 110012433
Overweight 11.51 9.81 10 575548 6454 110007287
Epstein-Barr virus antibody positive 11.50 9.81 16 575542 674 110013067
Hepatic haemorrhage 11.49 9.81 23 575535 1311 110012430
Incontinence 11.49 9.81 46 575512 16589 109997152
Abscess fungal 11.48 9.81 13 575545 443 110013298
Mucocutaneous leishmaniasis 11.48 9.81 14 575544 517 110013224
SARS-CoV-2 RNA 11.48 9.81 5 575553 32 110013709
Forced expiratory volume decreased 11.44 9.81 33 575525 13143 110000598
Cancer pain 11.44 9.81 11 575547 6761 110006980
Renal and pancreas transplant rejection 11.42 9.81 6 575552 61 110013680
Bronchospasm 11.41 9.81 221 575337 30018 109983723
Aspergillus test positive 11.41 9.81 20 575538 1030 110012711
Neuritis 11.39 9.81 13 575545 7386 110006355
Pharyngeal swelling 11.38 9.81 104 575454 11928 110001813
Glycosylated haemoglobin increased 11.37 9.81 74 575484 23545 109990196
Extrasystoles 11.37 9.81 16 575542 8302 110005439
Anuria 11.36 9.81 184 575374 24157 109989584
Coagulopathy 11.32 9.81 286 575272 40625 109973116
Diabetic macroangiopathy 11.30 9.81 8 575550 144 110013597
Beta 2 microglobulin increased 11.30 9.81 16 575542 685 110013056
Infectious thyroiditis 11.30 9.81 9 575549 195 110013546
Pneumonia lipoid 11.30 9.81 9 575549 195 110013546
Pneumonia staphylococcal 11.29 9.81 62 575496 6029 110007712
Hepatosplenomegaly 11.24 9.81 68 575490 6851 110006890
Mean cell volume decreased 11.22 9.81 59 575499 5643 110008098
Blindness 11.21 9.81 258 575300 36101 109977640
Hallucination, visual 11.21 9.81 142 575416 39463 109974278
Blood gases abnormal 11.21 9.81 23 575535 1335 110012406
Myocardial ischaemia 11.19 9.81 87 575471 26597 109987144
Emotional distress 11.18 9.81 165 575393 44682 109969059
Exposed bone in jaw 11.17 9.81 3 575555 3808 110009933
T-lymphocyte count decreased 11.16 9.81 15 575543 611 110013130
Myocardial calcification 11.16 9.81 10 575548 256 110013485
Pleural mass 11.16 9.81 7 575551 102 110013639
Larynx irritation 11.14 9.81 9 575549 199 110013542
Infusion related hypersensitivity reaction 11.14 9.81 18 575540 867 110012874
Catheter site erythema 11.14 9.81 9 575549 6019 110007722
Hand deformity 11.13 9.81 982 574576 217524 109796217
Osteosarcoma recurrent 11.12 9.81 8 575550 148 110013593
Necrotising bronchiolitis 11.11 9.81 4 575554 14 110013727
Diabetic neuropathy 11.10 9.81 12 575546 6987 110006754
Breast pain 11.10 9.81 22 575536 9978 110003763
Lip dry 11.10 9.81 632 574926 99451 109914290
Magnetic resonance imaging spinal abnormal 11.09 9.81 10 575548 258 110013483
Nephropathy 11.06 9.81 113 575445 13354 110000387
Foetal growth restriction 11.05 9.81 38 575520 3012 110010729
Cerebellar stroke 11.04 9.81 18 575540 874 110012867
Dust allergy 11.03 9.81 9 575549 5992 110007749
Lower gastrointestinal haemorrhage 11.02 9.81 54 575504 18432 109995309
Post infection glomerulonephritis 11.02 9.81 8 575550 150 110013591
Abnormal loss of weight 11.02 9.81 23 575535 10234 110003507
Anosmia 11.00 9.81 31 575527 12441 110001300
Prostate cancer metastatic 10.99 9.81 6 575552 4937 110008804
Vasculitis necrotising 10.99 9.81 25 575533 1558 110012183
Potentiating drug interaction 10.98 9.81 28 575530 11615 110002126
Arterial rupture 10.98 9.81 18 575540 878 110012863
Weight decreased 10.97 9.81 2209 573349 465848 109547893
Respiratory gas exchange disorder 10.95 9.81 18 575540 880 110012861
Pemphigoid 10.94 9.81 59 575499 19648 109994093
Tooth extraction 10.94 9.81 33 575525 12958 110000783
Injection site irritation 10.92 9.81 6 575552 4918 110008823
Toxic shock syndrome staphylococcal 10.90 9.81 4 575554 15 110013726
Device breakage 10.88 9.81 36 575522 13733 110000008
Hypotension 10.88 9.81 2487 573071 521362 109492379
Intermenstrual bleeding 10.88 9.81 12 575546 6922 110006819
Rosacea 10.88 9.81 55 575503 5181 110008560
Oral fungal infection 10.87 9.81 49 575509 4403 110009338
Viral myositis 10.86 9.81 6 575552 68 110013673
Encephalitis Japanese B 10.86 9.81 6 575552 68 110013673
Autoimmune haemolytic anaemia 10.85 9.81 93 575465 10474 110003267
Trichophytosis 10.85 9.81 13 575545 471 110013270
Productive cough 10.85 9.81 485 575073 113820 109899921
Oral discomfort 10.82 9.81 27 575531 11284 110002457
Allergy to chemicals 10.82 9.81 40 575518 3285 110010456
Diastolic dysfunction 10.82 9.81 31 575527 12373 110001368
Essential hypertension 10.82 9.81 15 575543 7832 110005909
Activated partial thromboplastin time prolonged 10.81 9.81 70 575488 22298 109991443
Lipodystrophy acquired 10.80 9.81 5 575553 4519 110009222
Enterocolitis bacterial 10.79 9.81 16 575542 715 110013026
Joint swelling 10.77 9.81 2086 573472 440759 109572982
Oropharyngeal plaque 10.75 9.81 13 575545 476 110013265
Hepatic infection 10.72 9.81 22 575536 1277 110012464
Wolff-Parkinson-White syndrome 10.72 9.81 12 575546 404 110013337
Granulocyte percentage 10.71 9.81 6 575552 70 110013671
Hyperammonaemia 10.70 9.81 114 575444 13618 110000123
Renal artery perforation 10.70 9.81 4 575554 16 110013725
Carotid artery insufficiency 10.70 9.81 4 575554 16 110013725
Foetal exposure during pregnancy 10.70 9.81 14 575544 7491 110006250
Limb mass 10.70 9.81 45 575513 3924 110009817
Aortic valve incompetence 10.67 9.81 26 575532 10955 110002786
Listeria sepsis 10.67 9.81 17 575541 809 110012932
Dermatitis contact 10.67 9.81 37 575521 13916 109999825
Adult T-cell lymphoma/leukaemia 10.67 9.81 12 575546 406 110013335
Bronchospasm paradoxical 10.67 9.81 9 575549 212 110013529
Lymphocytosis 10.66 9.81 56 575502 5355 110008386
Embolism 10.65 9.81 46 575512 16243 109997498
Renal hypertrophy 10.65 9.81 5 575553 39 110013702
Muscle spasms 10.63 9.81 1276 574282 276881 109736860
Vein collapse 10.63 9.81 22 575536 1285 110012456
Enuresis 10.63 9.81 4 575554 4092 110009649
Electric shock sensation 10.62 9.81 28 575530 1916 110011825
Malignant pleural effusion 10.61 9.81 4 575554 4089 110009652
Photopsia 10.60 9.81 10 575548 6204 110007537
Allergy test positive 10.58 9.81 18 575540 905 110012836
Arteritis coronary 10.57 9.81 6 575552 72 110013669
International normalised ratio fluctuation 10.56 9.81 4 575554 4076 110009665
Lymphoedema 10.49 9.81 41 575517 14888 109998853
Acne fulminans 10.48 9.81 10 575548 278 110013463
Toxic neuropathy 10.45 9.81 20 575538 1103 110012638
Glomerulonephritis proliferative 10.43 9.81 13 575545 491 110013250
Diffuse mesangial sclerosis 10.42 9.81 6 575552 74 110013667
Fear of injection 10.42 9.81 19 575539 8892 110004849
Jejunal perforation 10.41 9.81 12 575546 417 110013324
Haematochezia 10.40 9.81 493 575065 115031 109898710
Relapsing-remitting multiple sclerosis 10.39 9.81 29 575529 2053 110011688
Arterial spasm 10.38 9.81 8 575550 165 110013576
Cold type haemolytic anaemia 10.37 9.81 13 575545 494 110013247
Ventricular extrasystoles 10.37 9.81 72 575486 22569 109991172
Acute generalised exanthematous pustulosis 10.37 9.81 68 575490 21596 109992145
Accelerated idioventricular rhythm 10.36 9.81 10 575548 282 110013459
Snoring 10.36 9.81 12 575546 6772 110006969
Herpes ophthalmic 10.36 9.81 27 575531 1835 110011906
Excessive skin 10.33 9.81 7 575551 117 110013624
Porokeratosis 10.33 9.81 10 575548 283 110013458
Mucosal disorder 10.33 9.81 48 575510 4369 110009372
Pulmonary arterial pressure increased 10.32 9.81 7 575551 5120 110008621
Oesophageal pain 10.31 9.81 7 575551 5118 110008623
Ileocaecal resection 10.29 9.81 14 575544 577 110013164
Urinary casts present 10.28 9.81 7 575551 118 110013623
Anaesthetic complication 10.27 9.81 3 575555 3603 110010138
Actinomycosis 10.25 9.81 22 575536 1318 110012423
Injury associated with device 10.25 9.81 5 575553 4384 110009357
Upper-airway cough syndrome 10.24 9.81 45 575513 15812 109997929
Respiratory tract inflammation 10.23 9.81 19 575539 1024 110012717
Psychomotor skills impaired 10.23 9.81 13 575545 7045 110006696
Bulbar palsy 10.22 9.81 11 575547 354 110013387
Acute pulmonary histoplasmosis 10.22 9.81 10 575548 287 110013454
Hip arthroplasty 10.20 9.81 217 575341 55596 109958145
Glomerulonephropathy 10.17 9.81 11 575547 356 110013385
Palmar erythema 10.16 9.81 31 575527 2307 110011434
Cystic fibrosis 10.15 9.81 6 575552 4725 110009016
Pneumonia influenzal 10.14 9.81 43 575515 3762 110009979
Delirium 10.11 9.81 587 574971 134438 109879303
Decreased immune responsiveness 10.11 9.81 85 575473 9521 110004220
Bradycardia 10.10 9.81 685 574873 154832 109858909
Meningitis chemical 10.10 9.81 11 575547 359 110013382
Pericardial fibrosis 10.09 9.81 9 575549 229 110013512
Stenotrophomonas sepsis 10.09 9.81 9 575549 229 110013512
Schistocytosis 10.09 9.81 6 575552 79 110013662
Product distribution issue 10.07 9.81 5 575553 4341 110009400
Activated partial thromboplastin time shortened 10.05 9.81 19 575539 1038 110012703
C-reactive protein abnormal 10.05 9.81 562 574996 129133 109884608
Enterobacter pneumonia 10.04 9.81 14 575544 591 110013150
Blood lactate dehydrogenase increased 10.03 9.81 302 575256 44032 109969709
Myelodysplastic syndrome 10.02 9.81 136 575422 37348 109976393
Cytopenia 10.01 9.81 216 575342 29900 109983841
Brain oedema 10.01 9.81 222 575336 30876 109982865
Pulmonary pneumatocele 9.99 9.81 4 575554 20 110013721
Creatinine urine increased 9.99 9.81 13 575545 513 110013228
Inadequate aseptic technique in use of product 9.98 9.81 7 575551 124 110013617
Lymphocyte count increased 9.98 9.81 68 575490 7135 110006606
Haematuria traumatic 9.97 9.81 11 575547 364 110013377
Aortic valve stenosis 9.95 9.81 11 575547 6339 110007402
Marrow hyperplasia 9.95 9.81 26 575532 1770 110011971
Gastrointestinal motility disorder 9.94 9.81 14 575544 7262 110006479
Haematoma 9.93 9.81 230 575328 58246 109955495
Haemoglobinuria 9.92 9.81 17 575541 860 110012881
Performance status decreased 9.91 9.81 14 575544 7252 110006489
Ependymoma 9.89 9.81 7 575551 126 110013615
Oxygen consumption increased 9.88 9.81 9 575549 5676 110008065
Influenza 9.87 9.81 1015 574543 168086 109845655
Epigastric discomfort 9.87 9.81 20 575538 8995 110004746
Gastroenteritis salmonella 9.86 9.81 22 575536 1353 110012388
Asymptomatic bacteriuria 9.86 9.81 12 575546 442 110013299
Genital haemorrhage 9.86 9.81 14 575544 7238 110006503
Chronic hepatitis C 9.86 9.81 15 575543 686 110013055
Coombs direct test positive 9.86 9.81 13 575545 520 110013221
Wrong product administered 9.85 9.81 27 575531 10933 110002808
Eosinophil count abnormal 9.84 9.81 19 575539 1055 110012686
Chronic papillomatous dermatitis 9.83 9.81 6 575552 83 110013658
Complement factor C3 decreased 9.83 9.81 11 575547 370 110013371
Pathological fracture 9.83 9.81 31 575527 12001 110001740
Carpal tunnel syndrome 9.82 9.81 73 575485 22537 109991204
Cerebral haemorrhage 9.82 9.81 260 575298 64708 109949033
Infusion site pain 9.82 9.81 136 575422 17283 109996458
Pulmonary necrosis 9.81 9.81 14 575544 604 110013137

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000932 Antiemetics
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones
MeSH PA D018696 Neuroprotective Agents
MeSH PA D020011 Protective Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018931 Antineoplastic Agents, Hormonal
CHEBI has role CHEBI:22587 antiviral agent
CHEBI has role CHEBI:33281 antimicrobial agent
CHEBI has role CHEBI:33282 antibacterial agent
CHEBI has role CHEBI:35480 analgesic
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:35623 anticonvulsant
CHEBI has role CHEBI:35705 immunosuppressive agent
CHEBI has role CHEBI:35842 antirheumatic drug
CHEBI has role CHEBI:50177 dermatologic drug
CHEBI has role CHEBI:65023 anti-asthmatic agent
CHEBI has role CHEBI:75835 anti-anaemic agent
CHEBI has role CHEBI:233423 antifibrotic agent

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Nephrotic syndrome indication 52254009 DOID:1184




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.23 acidic
pKa2 12.63 acidic
pKa3 13.35 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST CHEMBL CHEMBL

External reference:

IDSource
4018069 VUID
N0000179635 NUI
D00751 KEGG_DRUG
2375-03-3 SECONDARY_CAS_RN
4018068 VANDF
4018069 VANDF
C0025819 UMLSCUI
CHEBI:135765 CHEBI
CHEMBL1201265 ChEMBL_ID
CHEMBL1201081 ChEMBL_ID
DB14644 DRUGBANK_ID
16923 PUBCHEM_CID
203189 RXNORM
1041 MMSL
4854 MMSL
5093 MMSL
5095 MMSL
d00293 MMSL
002160 NDDF
002162 NDDF
005280 NDDF
116593003 SNOMEDCT_US
27242001 SNOMEDCT_US
412248005 SNOMEDCT_US
734654003 SNOMEDCT_US
D008776 MESH_DESCRIPTOR_UI
C0025815 UMLSCUI
DB00959 DRUGBANK_ID
6741 PUBCHEM_CID
732 INN_ID
D008775 MESH_DESCRIPTOR_UI
5GMR90S4KN UNII
CHEBI:6888 CHEBI
5GMR90S4KN INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0003 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0018 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0039 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0039 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0698 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0698 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0758 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0850 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS NDA 22 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9182 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 20 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9753 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAMUSCULAR ANDA 20 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9754 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAMUSCULAR ANDA 20 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9850 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAMUSCULAR ANDA 22 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9851 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 22 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0404-9957 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0404-9958 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 13 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-127 INJECTION 40 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-128 INJECTION 500 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-129 INJECTION 125 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-130 INJECTION 1 g INTRAVENOUS ANDA 19 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 50090-0271 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 51662-1263 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAMUSCULAR NDA 13 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 51662-1264 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAMUSCULAR NDA 13 sections
SOLU-MEDROL(R) METHYLPREDNISOLONE SODIUM SUCCINAT HUMAN PRESCRIPTION DRUG LABEL 1 51662-1483 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAMUSCULAR NDA 13 sections
METHYLPREDNISOLONE SODIUM SUCCINATE HUMAN PRESCRIPTION DRUG LABEL 1 51662-1695 INJECTION 125 mg INTRAVENOUS ANDA 12 sections
Methylprednisolone Sodium Succinate Human Prescription Drug Label 1 55150-262 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 40 mg INTRAMUSCULAR ANDA 19 sections
Methylprednisolone Sodium Succinate Human Prescription Drug Label 1 55150-263 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 125 mg INTRAMUSCULAR ANDA 19 sections
Methylprednisolone Sodium Succinate Human Prescription Drug Label 1 55150-264 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 500 mg INTRAMUSCULAR ANDA 19 sections
Methylprednisolone Sodium Succinate Human Prescription Drug Label 1 55150-265 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2 g INTRAMUSCULAR ANDA 19 sections