DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
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L1000
FAQ
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
aminopicoline 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
172
695-34-1
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
aminopicoline hydrochloride
2-amino-4-picoline
aminopicoline
2-amino-4-methylpyridine
aminton
ascensil
Molecular weight: 108.14
Formula: C6H8N2
CLOGP: 0.82
LIPINSKI: 0
HAC: 2
HDO: 1
TPSA: 38.91
ALOGS: 0.24
ROTB: 0
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
7.1
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Nitric oxide synthase, inducible
Enzyme
P35228
NOS2_HUMAN
INHIBITOR
IC50
7.40
IUPHAR
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External reference:
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ID
Source
BVF
PDB_CHEM_ID
1533
PUBCHEM_CID
394N1Z644H
UNII
5111
IUPHAR_LIGAND_ID
C0045846
UMLSCUI
C015672
MESH_SUPPLEMENTAL_RECORD_UI
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Pharmaceutical products:
None
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aminopicoline