mabuterol Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
bronchodilators, phenethylamine derivatives 1623 56341-08-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • broncholin
  • mabuterol
  • ambuterol
  • mabuterol hydrochloride
  • mabuterol HCl
  • Molecular weight: 310.75
  • Formula: C13H18ClF3N2O
  • CLOGP: 2.77
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 3
  • TPSA: 58.28
  • ALOGS: -3.89
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D018663 Adrenergic Agents
MeSH PA D000322 Adrenergic Agonists
MeSH PA D000318 Adrenergic beta-Agonists
MeSH PA D018927 Anti-Asthmatic Agents
MeSH PA D001993 Bronchodilator Agents
MeSH PA D018377 Neurotransmitter Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D019141 Respiratory System Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.64 Basic
pKa2 0.32 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01589 KEGG_DRUG
54240-36-7 SECONDARY_CAS_RN
C0065464 UMLSCUI
CHEBI:135325 CHEBI
CHEMBL86749 ChEMBL_ID
C044573 MESH_SUPPLEMENTAL_RECORD_UI
3995 PUBCHEM_CID
5089 INN_ID
R4K19W6S7Q UNII
008207 NDDF
008208 NDDF

Pharmaceutical products:

None