levopropoxyphene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1573 2338-37-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • levopropoxyphene
  • l-Propoxyphene
  • levopropoxyphene napsylate
  • levopropoxyphene napsylate anhydrous
  • novrad
A propionate derivative that is used to suppress coughing.
  • Molecular weight: 339.48
  • Formula: C22H29NO2
  • CLOGP: 5.21
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 0
  • TPSA: 29.54
  • ALOGS: -4.91
  • ROTB: 9
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
March 21, 1962 FDA LILLY

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:51177 anti-tussive
MeSH PA D000996 Antitussive Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D019141 Respiratory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.26 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000178576 NUI
D04718 KEGG_DRUG
C0023582 UMLSCUI
CHEBI:51174 CHEBI
CHEMBL1213351 ChEMBL_ID
CHEMBL1738990 ChEMBL_ID
DB06793 DRUGBANK_ID
D054816 MESH_DESCRIPTOR_UI
200742 PUBCHEM_CID
731 INN_ID
55557-30-7 SECONDARY_CAS_RN
5714-90-9 SECONDARY_CAS_RN
U75VZ9PK1J UNII
402519 RXNORM
001655 NDDF
004670 NDDF
20413008 SNOMEDCT_US
CHEMBL1593906 ChEMBL_ID

Pharmaceutical products:

None