kebuzone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-inflammatory analgesics, phenylbutazone derivatives 1522 853-34-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • kebuzone
  • chebutan
  • chetazol
  • chetazolidin
  • ketanol
  • ketazon
  • ketazone
  • ketophenylbutazone
proposed antirheumatic agent; minor descriptor (75-86); on-line & INDEX MEDICUS search PHENYLBUTAZONE/AA
  • Molecular weight: 322.36
  • Formula: C19H18N2O3
  • CLOGP: 0.90
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 0
  • TPSA: 57.69
  • ALOGS: -3.45
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M01AA06 MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Butylpyrazolidines
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents
CHEBI has role CHEBI:35475 non-steroidal anti-inflammatory agent

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.38 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01567 KEGG_DRUG
C0064324 UMLSCUI
CHEBI:31749 CHEBI
CHEMBL2107720 ChEMBL_ID
DB08940 DRUGBANK_ID
C100280 MESH_SUPPLEMENTAL_RECORD_UI
3824 PUBCHEM_CID
2444 INN_ID
4VD83UL6Y6 UNII
28198 RXNORM
004197 NDDF

Pharmaceutical products:

None