famprofazone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-inflammatory analgesics, phenylbutazone derivatives 1130 22881-35-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • famprofazone
  • gewodin
  • Molecular weight: 391.56
  • Formula: C25H33N3O
  • CLOGP: 3.07
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 26.79
  • ALOGS: -3.83
  • ROTB: 8

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.66 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Nuclear receptor subfamily 2 group E member 1 Nuclear hormone receptor Kd 5.18 SCIENTIFIC LITERATURE

External reference:

IDSource
C0170987 UMLSCUI
CHEBI:135587 CHEBI
CHEMBL1475693 ChEMBL_ID
DB16702 DRUGBANK_ID
C076013 MESH_SUPPLEMENTAL_RECORD_UI
3326 PUBCHEM_CID
2645 INN_ID
HN0NCX453C UNII
007128 NDDF

Pharmaceutical products:

None