etifoxine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1099 21715-46-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • etifoxine hydrochloride
  • etafenoxine hydrochloride
  • etafenoxine
  • etifoxine
  • etifoxin
  • Molecular weight: 300.79
  • Formula: C17H17ClN2O
  • CLOGP: 5.29
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 1
  • TPSA: 33.62
  • ALOGS: -5.14
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Cutaneous T-cell lymphoma 63.14 58.82 11 594 1369 63487048

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Cutaneous T-cell lymphoma 53.88 48.92 11 888 2692 79740797

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05BX03 NERVOUS SYSTEM
PSYCHOLEPTICS
ANXIOLYTICS
Other anxiolytics
MeSH PA D014151 Anti-Anxiety Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D011619 Psychotropic Drugs
MeSH PA D014149 Tranquilizing Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.57 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07320 KEGG_DRUG
56776-32-0 SECONDARY_CAS_RN
C0059678 UMLSCUI
CHEBI:135272 CHEBI
CHEMBL2106227 ChEMBL_ID
DB08986 DRUGBANK_ID
C002125 MESH_SUPPLEMENTAL_RECORD_UI
135413553 PUBCHEM_CID
5468 IUPHAR_LIGAND_ID
2846 INN_ID
X24X82MX4X UNII
236215 RXNORM
005416 NDDF
005417 NDDF

Pharmaceutical products:

None