ethinamate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
tranquillizers, propanediol and pentanediol derivatives 1081 126-52-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • 1-Ethinylcyclohexyl carbamate
  • 1-Ethynylcyclohexanol carbamate
  • 1-Ethynylcyclohexyl carbamate
  • valamin
  • valmid
  • valmidate
  • volamin
  • ethinamate
short duration hypnotic with fast onset & relatively low toxicity; may cause dependence; minor descriptor (76-85); on-line & Index Medicus search CARBAMATES (76-85)
  • Molecular weight: 167.21
  • Formula: C9H13NO2
  • CLOGP: 1.74
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 52.32
  • ALOGS: -3.20
  • ROTB: 2
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,CAMK2D,CDK5,CDK9,EIF2AK3,ERBB2,GRK2,ITK,MAPK7,PDK1,PDK2,PRKDC,TEK 15
kinase-selectivity-class AXL,EIF2AK3,GRK2 3
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA DISTA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:35717 sedative

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Insomnia indication 193462001




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019086 VUID
N0000147346 NUI
D00703 KEGG_DRUG
4019086 VANDF
C0059714 UMLSCUI
CHEBI:4884 CHEBI
CHEMBL1576 ChEMBL_ID
DB01031 DRUGBANK_ID
3284 PUBCHEM_CID
549 INN_ID
C100198 MESH_SUPPLEMENTAL_RECORD_UI
7325 IUPHAR_LIGAND_ID
IAN371PP48 UNII
24474 RXNORM
001431 NDDF
54717003 SNOMEDCT_US
IAN371PP48 INXIGHT DRUGS

Pharmaceutical products:

None