ethaverine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
spasmolytics with a papaverine-like action 1077 486-47-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ethquinol
  • ethaverine
  • barbonin
  • barbonine
  • dyscural
  • ethylpapaverine
  • ethaverine hydrochloride
  • ethaverine HCl
tetraethyl homolog of papaverine; smooth muscle relaxant; RN given refers to parent cpd; structure
  • Molecular weight: 395.50
  • Formula: C24H29NO4
  • CLOGP: 5.90
  • LIPINSKI: 1
  • HAC: 5
  • HDO: 0
  • TPSA: 49.81
  • ALOGS: -5.65
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D010276 Parasympatholytics
MeSH PA D018373 Peripheral Nervous System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Cerebral ischemia indication 287731003
Peripheral vascular disease indication 400047006
Glaucoma contraindication 23986001 DOID:1686
Complete atrioventricular block contraindication 27885002
Heart block contraindication 233916004
Complete Atrioventricular Dissociation contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.36 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019748 VUID
N0000147839 NUI
D07926 KEGG_DRUG
4018894 VANDF
4019748 VANDF
C0059703 UMLSCUI
CHEBI:94592 CHEBI
CHEMBL1555736 ChEMBL_ID
C007639 MESH_SUPPLEMENTAL_RECORD_UI
3280 PUBCHEM_CID
299 INN_ID
985-13-7 SECONDARY_CAS_RN
2H2HC19DYZ UNII
235229 RXNORM
2473 MMSL
4696 MMSL
d00696 MMSL
000697 NDDF
004523 NDDF
49451008 SNOMEDCT_US
CHEMBL1316965 ChEMBL_ID

Pharmaceutical products:

None