erythromycin ethyl succinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 1051 1264-62-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • erythromycin ethylsuccinate
  • erythromycin ethyl succinate
  • anamycin
  • arpimycin
  • eritrocina
  • erythrocin ethyl succinate
A macrolide antibiotic, produced by Streptomyces erythreus. This compound is an ester of erythromycin base and succinic acid. It acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
  • Molecular weight: 862.06
  • Formula: C43H75NO16
  • CLOGP: 3.25
  • LIPINSKI: 2
  • HAC: 17
  • HDO: 4
  • TPSA: 226.28
  • ALOGS: -3.76
  • ROTB: 14
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 35 %

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
azlogd74 LogD at pH 7.4 2.453 High 1
caco2-efflux Caco-2 efflux ratio (BA/AB) 26.792 High 1
caco2-intrinsic-papp Caco-2 intrinsic apparent permeability 6.353 10^-6 cm/s High 1
dh-clint Dog hepatocyte intrinsic clearance 28.184 uL/min/10^6 cells High 1
dppb Dog plasma protein binding (% unbound) 21.910 % High 1
fcs-ppb Fetal calf serum protein binding (% unbound) 31.070 % High 1
herg hERG pIC50 4.393 pIC50 High 1
hh-clint Human hepatocyte intrinsic clearance 16.255 uL/min/10^6 cells High 1
hlm-clint Human liver microsomal intrinsic clearance 127.350 uL/min/mg protein High 1
hppb Human plasma protein binding (% unbound) 23.110 % High 1
kinase-safety-class ACVR2B,AXL,CAMK2D,CDK5,CDK9,EIF2AK3,ERBB2,GRK2,ITK,MAP2K6,MAP3K21,MAPK7,NTRK2,PDK1,PDK2,PDK4,PRKDC,TEK 18
mdck-mdr1-bcrp-efflux MDCK-MDR1-BCRP efflux ratio 2.415 Moderate 0.79
mdck-mdr1-efflux MDCK-MDR1 efflux ratio 12.560 High 1
mh-clint Mouse hepatocyte intrinsic clearance 49.317 High 1
mppb Mouse plasma protein binding (% unbound) 18.810 High 1
nih-mdck-mdr1-efflux NIH MDCK-MDR1 efflux ratio 21.429 High 1
pfas-class PFAS structural alert (1 = True, 0 = False) 0
pld-class Phospholipidosis risk class (1 = positive, 0 = negative) 0 Moderate 0.79
pppb Pig plasma protein binding (% unbound) 26.770 % High 1
rat-kpuu-brain Rat brain Kpuu 0.013 % Moderate 0.79
rh-clint Rat hepatocyte intrinsic clearance 46.666 uL/min/10^6 cells High 1
rh-fuinc Rat hepatocyte fraction unbound in incubation 62.780 % High 1
rppb Rat plasma protein binding (% unbound) 19.820 % High 1
solubility-dd Solubility at pH 7.4 in DMSO 298.538 uM High 1

Approvals:

DateAgencyCompanyOrphan
April 2, 1965 FDA ARBOR PHARMS LLC

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug hypersensitivity 3545.88 12.62 2497 46510 461112 90118328
International normalised ratio fluctuation 262.49 12.62 88 48919 3005 90576435
Bloody discharge 210.49 12.62 69 48938 2194 90577246
Grip strength 207.61 12.62 100 48907 8865 90570575
Lyme disease 164.50 12.62 68 48939 4194 90575246
Breast cancer stage III 135.43 12.62 196 48811 84251 90495189
Porphyria acute 133.65 12.62 96 48911 17879 90561561
Dislocation of vertebra 126.98 12.62 154 48853 55814 90523626
Adjustment disorder with depressed mood 115.68 12.62 148 48859 56605 90522835
Drug tolerance decreased 104.97 12.62 107 48900 32023 90547417
Abortion spontaneous 103.98 12.62 137 48870 53919 90525521
Lupus vulgaris 103.86 12.62 125 48882 44934 90534506
Foot deformity 100.84 12.62 142 48865 59509 90519931
Bone erosion 95.29 12.62 130 48877 52891 90526549
Autoimmune disorder 92.21 12.62 156 48851 76588 90502852
Exostosis 87.61 12.62 125 48882 53009 90526431
Retinitis 87.51 12.62 106 48901 38352 90541088
X-ray abnormal 87.17 12.62 115 48892 45309 90534131
Sleep disorder due to a general medical condition 83.91 12.62 112 48895 44626 90534814
Laryngitis 81.63 12.62 118 48889 50635 90528805
Ear infection 80.09 12.62 139 48868 69636 90509804
Laboratory test abnormal 78.83 12.62 105 48902 41749 90537691
Seronegative arthritis 77.10 12.62 70 48937 18164 90561276
Amnesia 75.05 12.62 175 48832 108330 90471110
Death 74.78 12.62 82 48925 456469 90122971
Colitis ulcerative 74.38 12.62 124 48883 60142 90519298
Swollen joint count 73.15 12.62 50 48957 8603 90570837
Hepatic cirrhosis 71.29 12.62 125 48882 63128 90516312
Wound infection 69.68 12.62 168 48839 106234 90473206
Frequent bowel movements 68.73 12.62 116 48891 56819 90522621
Delirium 68.58 12.62 165 48842 104194 90475246
Maternal exposure timing unspecified 66.49 12.62 71 48936 22412 90557028
Deep vein thrombosis postoperative 64.85 12.62 128 48879 70681 90508759
Grip strength decreased 62.59 12.62 148 48859 92428 90487012
Walking aid user 62.20 12.62 86 48921 35420 90544020
Neutropenia 62.10 12.62 22 48985 224882 90354558
Pain 61.95 12.62 303 48704 996038 89583402
Rectal haemorrhage 61.14 12.62 137 48870 82607 90496833
Visual impairment 59.55 12.62 182 48825 132183 90447257
Maternal exposure during pregnancy 59.38 12.62 365 48642 359698 90219742
Wheezing 56.70 12.62 267 48740 237813 90341627
Exposure during pregnancy 56.51 12.62 267 48740 238143 90341297
White blood cell count increased 55.00 12.62 116 48891 67125 90512315
Anaphylactic reaction 54.96 12.62 136 48871 87388 90492052
Anaemia 54.88 12.62 66 48941 352736 90226704
Hypotension 54.85 12.62 57 48950 325340 90254100
Bursitis 54.60 12.62 176 48831 131478 90447962
Completed suicide 54.58 12.62 7 49000 145051 90434389
Pancreatitis 54.28 12.62 118 48889 69708 90509732
Fall 54.21 12.62 112 48895 481698 90097742
Amniotic cavity infection 52.95 12.62 22 48985 1374 90578066
Monocytosis 52.87 12.62 20 48987 974 90578466
Lupus-like syndrome 51.79 12.62 94 48913 48752 90530688
Road traffic accident 51.25 12.62 151 48856 107475 90471965
Iron deficiency 50.97 12.62 42 48965 9570 90569870
Ulcerative keratitis 49.69 12.62 28 48979 3425 90576015
Drug ineffective 49.08 12.62 496 48511 1383802 89195638
C-reactive protein abnormal 46.34 12.62 163 48844 127266 90452174
Spondylitis 45.91 12.62 47 48960 14131 90565309
Feeling hot 44.60 12.62 117 48890 77891 90501549
Pulmonary fibrosis 43.92 12.62 143 48864 107360 90472080
Toxicity to various agents 43.54 12.62 55 48952 287791 90291649
Off label use 43.23 12.62 385 48622 1101867 89477573
Joint range of motion decreased 42.20 12.62 165 48842 135478 90443962
Faecal volume decreased 40.80 12.62 12 48995 264 90579176
Anti-cyclic citrullinated peptide antibody 40.47 12.62 61 48946 27160 90552280
Rheumatic fever 40.36 12.62 177 48830 152944 90426496
Asthma 40.20 12.62 246 48761 241914 90337526
Acute kidney injury 39.02 12.62 71 48936 320316 90259124
Pregnancy 38.51 12.62 96 48911 61951 90517489
Swollen joint count increased 36.83 12.62 138 48869 111068 90468372
Oedema 36.80 12.62 209 48798 200086 90379354
Febrile neutropenia 36.59 12.62 20 48987 158329 90421111
Forced expiratory volume decreased 36.41 12.62 28 48979 5780 90573660
Disease progression 35.87 12.62 20 48987 156595 90422845
Peripheral venous disease 35.52 12.62 113 48894 83808 90495632
Rheumatoid factor positive 34.81 12.62 184 48823 171466 90407974
Red blood cell sedimentation rate increased 34.76 12.62 111 48896 82484 90496956
Platelet count increased 34.27 12.62 49 48958 20810 90558630
Intentional overdose 34.18 12.62 5 49002 93829 90485611
Hypercholesterolaemia 34.08 12.62 126 48881 100766 90478674
Umbilical erythema 33.80 12.62 8 48999 72 90579368
Mass excision 33.48 12.62 11 48996 352 90579088
Abdominal pain upper 33.47 12.62 300 48707 332374 90247066
Weight fluctuation 33.34 12.62 47 48960 19702 90559738
Injection site pain 33.31 12.62 27 48980 173672 90405768
Exposure to SARS-CoV-2 32.91 12.62 19 48988 2433 90577007
Memory impairment 32.48 12.62 200 48807 197044 90382396
Malignant neoplasm progression 32.08 12.62 9 48998 106861 90472579
Respiratory disorder 31.87 12.62 92 48915 64724 90514716
Infection 31.68 12.62 317 48690 361777 90217663
Product dose omission issue 30.13 12.62 71 48936 291616 90287824
Hyponatraemia 29.23 12.62 18 48989 133520 90445920
Secretion discharge 28.59 12.62 39 48968 15857 90563583
Vomiting 28.00 12.62 589 48418 787704 89791736
Purpura senile 27.82 12.62 11 48996 604 90578836
Type 2 diabetes mellitus 27.37 12.62 196 48811 203048 90376392
Mobility decreased 27.23 12.62 230 48777 250504 90328936
Drug abuse 26.52 12.62 6 49001 82341 90497099
White blood cell count decreased 26.23 12.62 31 48976 167078 90412362
Pneumococcal infection 26.16 12.62 13 48994 1232 90578208
Urticaria 26.01 12.62 271 48736 312463 90266977
Necrosis ischaemic 25.80 12.62 12 48995 983 90578457
Haemoglobin decreased 25.47 12.62 30 48977 161926 90417514
Blood cholesterol increased 25.40 12.62 196 48811 207816 90371624
Lip dry 25.31 12.62 115 48892 100840 90478600
Vertigo positional 25.18 12.62 18 48989 3326 90576114
Sciatica 25.06 12.62 115 48892 101267 90478173
Tarsal tunnel syndrome 24.99 12.62 10 48997 567 90578873
Serum sickness-like reaction 24.80 12.62 10 48997 578 90578862
Facet joint syndrome 24.61 12.62 112 48895 98277 90481163
Contusion 24.46 12.62 225 48782 250991 90328449
Death neonatal 24.43 12.62 15 48992 2150 90577290
SARS-CoV-2 test positive 24.22 12.62 30 48977 11098 90568342
Overdose 23.97 12.62 30 48977 157679 90421761
Osteoporosis 23.49 12.62 109 48898 96422 90483018
Ototoxicity 23.17 12.62 14 48993 1950 90577490
Atrial fibrillation 22.95 12.62 23 48984 133588 90445852
Pancytopenia 22.68 12.62 19 48988 120244 90459196
Bronchial obstruction 22.44 12.62 13 48994 1676 90577764
Muscular weakness 22.13 12.62 189 48818 206477 90372963
Live birth 22.03 12.62 93 48914 79014 90500426
Eye inflammation 21.82 12.62 24 48983 7827 90571613
Periumbilical abscess 21.43 12.62 7 49000 220 90579220
Prescribed overdose 21.42 12.62 107 48900 97518 90481922
Joint dislocation 20.69 12.62 62 48945 44520 90534920
Lower limb fracture 20.69 12.62 96 48911 84917 90494523
Catheter site abscess 20.63 12.62 7 49000 248 90579192
Liver disorder 20.61 12.62 124 48883 121145 90458295
Premature baby 20.19 12.62 43 48964 25034 90554406
Lip swelling 20.14 12.62 56 48951 38554 90540886
Stevens-Johnson syndrome 19.88 12.62 47 48960 29329 90550111
Corneal neovascularisation 19.86 12.62 6 49001 145 90579295
Platelet count decreased 19.84 12.62 27 48980 136942 90442498
Duodenal ulcer perforation 19.46 12.62 194 48813 221094 90358346
Urinary tract infection 19.43 12.62 92 48915 305540 90273900
Dysphoria 19.20 12.62 20 48987 6134 90573306
Hypoglycaemia 18.98 12.62 7 49000 69841 90509599
Pharyngeal swelling 18.80 12.62 25 48982 9919 90569521
Caesarean section 18.74 12.62 35 48972 18542 90560898
Staphylococcal infection 18.50 12.62 63 48944 48376 90531064
Benign laryngeal neoplasm 18.32 12.62 4 49003 24 90579416
Constipation 18.06 12.62 84 48923 280311 90299129
Obesity 18 12.62 108 48899 105399 90474041
Resorption bone increased 17.85 12.62 10 48997 1209 90578231
Beta haemolytic streptococcal infection 17.69 12.62 13 48994 2506 90576934
Spinal fusion surgery 17.51 12.62 27 48980 12256 90567184
Arthritis 17.37 12.62 152 48855 167163 90412277
Dehydration 17.28 12.62 51 48956 194396 90385044
Pneumonia streptococcal 17.22 12.62 12 48995 2129 90577311
Jarisch-Herxheimer reaction 16.97 12.62 7 49000 429 90579011
Suicide attempt 16.73 12.62 10 48997 75389 90504051
Flushing 16.66 12.62 14 48993 88477 90490963
Blood pressure increased 16.62 12.62 53 48954 197164 90382276
Respiratory failure 16.50 12.62 24 48983 118394 90461046
Cerebrovascular accident 16.28 12.62 26 48981 123507 90455933
Blister 16.28 12.62 210 48797 254788 90324652
Fatigue 16.23 12.62 488 48519 1153535 89425905
Cardio-respiratory arrest 16.06 12.62 7 49000 63133 90516307
Injury 15.91 12.62 170 48837 197179 90382261
Vestibular disorder 15.64 12.62 10 48997 1539 90577901
Pancreatic pseudocyst 15.63 12.62 8 48999 807 90578633
Therapeutic product effect incomplete 15.62 12.62 167 48840 193729 90385711
Symblepharon 15.58 12.62 6 49001 307 90579133
Haemorrhagic diathesis 15.55 12.62 17 48990 5507 90573933
Pancreatic mass 15.24 12.62 9 48998 1202 90578238
Hypokalaemia 15.12 12.62 30 48977 131086 90448354
Gastrointestinal disorder 14.99 12.62 208 48799 256479 90322961
Night sweats 14.97 12.62 120 48887 128646 90450794
Anxiety 14.97 12.62 243 48764 309529 90269911
Neoplasm progression 14.82 12.62 3 49004 44483 90534957
Eye pain 14.77 12.62 55 48952 44113 90535327
Joint stiffness 14.69 12.62 82 48925 77960 90501480
Corneal perforation 14.68 12.62 7 49000 606 90578834
Sepsis 14.68 12.62 49 48958 179765 90399675
Injection site swelling 14.65 12.62 7 49000 59832 90519608
Blood glucose increased 14.59 12.62 18 48989 95228 90484212
Cystitis 14.59 12.62 9 48998 66709 90512731
Cardiac failure 14.47 12.62 23 48984 109473 90469967
Hip arthroplasty 14.29 12.62 80 48927 76128 90503312
Coma 14.28 12.62 11 48996 72621 90506819
Hypoaesthesia 14.27 12.62 244 48763 313966 90265474
Oral pain 13.81 12.62 44 48963 32639 90546801
Urticarial vasculitis 13.77 12.62 8 48999 1037 90578403
Premature rupture of membranes 13.76 12.62 16 48991 5542 90573898
Cardiac failure congestive 13.75 12.62 20 48987 98674 90480766
Mucosal inflammation 13.71 12.62 7 49000 57618 90521822
Blood creatinine increased 13.68 12.62 21 48986 101365 90478075
Diplegia 13.61 12.62 9 48998 1466 90577974
Ergot poisoning 13.47 12.62 4 49003 91 90579349
Leukopenia 13.46 12.62 21 48986 100689 90478751
Sleep disorder due to general medical condition, insomnia type 13.40 12.62 117 48890 128577 90450863
Anal candidiasis 13.34 12.62 3 49004 21 90579419
Morbid thoughts 13.31 12.62 7 49000 747 90578693
Photophobia 13.29 12.62 33 48974 21236 90558204
Somnolence 13.25 12.62 63 48944 209021 90370419
Fluid retention 13.13 12.62 17 48990 88074 90491366
Vaginal lesion 13.13 12.62 6 49001 472 90578968
Sleep disorder 13.02 12.62 164 48843 197866 90381574
Chest pain 13.02 12.62 244 48763 319401 90260039
Thinking abnormal 12.97 12.62 23 48984 11709 90567731
Infantile haemangioma 12.97 12.62 4 49003 104 90579336
Appetite disorder 12.91 12.62 20 48987 9113 90570327
Dry mouth 12.78 12.62 154 48853 183905 90395535
Economic problem 12.71 12.62 12 48995 3269 90576171
Drug interaction 12.67 12.62 215 48792 276238 90303202

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug hypersensitivity 452.82 14.31 293 10576 99096 42511370
Hyphaema 74.02 14.31 20 10849 700 42609766
Rhabdomyolysis 73.68 14.31 95 10774 77924 42532542
Drug interaction 69.65 14.31 186 10683 266813 42343653
Toxic epidermal necrolysis 66.73 14.31 55 10814 26695 42583771
Product packaging issue 59.03 14.31 17 10852 754 42609712
Anti factor V antibody 58.34 14.31 14 10855 301 42610165
Porphyria acute 49.62 14.31 13 10856 403 42610063
Premature baby 48.35 14.31 43 10826 23110 42587356
Eye pain 44.53 14.31 36 10833 16994 42593472
Dystonia 39.86 14.31 30 10839 12760 42597706
Low birth weight baby 39.40 14.31 27 10842 9928 42600538
Hyperoxaluria 39.07 14.31 9 10860 161 42610305
Stupor 38.77 14.31 18 10851 3135 42607331
Injection site extravasation 35.85 14.31 17 10852 3105 42607361
Pyloric stenosis 35.36 14.31 12 10857 916 42609550
Intraocular pressure increased 34.20 14.31 21 10848 6412 42604054
Obstruction gastric 33.71 14.31 12 10857 1056 42609410
Acute generalised exanthematous pustulosis 33.28 14.31 23 10846 8572 42601894
Crystal nephropathy 31.18 14.31 10 10859 639 42609827
Foetal death 30.51 14.31 8 10861 249 42610217
Coagulation time prolonged 30.28 14.31 12 10857 1420 42609046
Measles 28.79 14.31 8 10861 311 42610155
Brain oedema 27.66 14.31 27 10842 16300 42594166
Deafness bilateral 27.09 14.31 11 10858 1386 42609080
Torsade de pointes 26.43 14.31 20 10849 8574 42601892
Hepatic failure 26.36 14.31 40 10829 38060 42572406
Product dispensing error 26.24 14.31 19 10850 7620 42602846
Cellulitis enterococcal 26.06 14.31 6 10863 107 42610359
Learning disorder 25.91 14.31 10 10859 1103 42609363
Skin wrinkling 25.53 14.31 8 10861 474 42609992
Foetal arrhythmia 24.83 14.31 6 10863 133 42610333
Ototoxicity 24.69 14.31 12 10857 2313 42608153
Pathogen resistance 23.37 14.31 21 10848 11429 42599037
Onychophagia 23.12 14.31 5 10864 66 42610400
Caesarean section 22.76 14.31 11 10858 2095 42608371
Clonal haematopoiesis 22.69 14.31 6 10863 193 42610273
Oligohydramnios 22.62 14.31 7 10862 398 42610068
Skin necrosis 22.36 14.31 16 10853 6298 42604168
Swelling face 22.07 14.31 31 10838 27523 42582943
Myoglobinuria 21.53 14.31 8 10861 795 42609671
Oculogyric crisis 21.46 14.31 10 10859 1755 42608711
Hepatic necrosis 21.38 14.31 13 10856 3900 42606566
Myasthenia gravis crisis 21.12 14.31 8 10861 838 42609628
Sepsis neonatal 20.37 14.31 6 10863 288 42610178
Respiratory acidosis 20.06 14.31 15 10854 6316 42604150
Potentiating drug interaction 19.77 14.31 15 10854 6453 42604013
Vasculitic rash 19.63 14.31 8 10861 1018 42609448
Cerebral haematoma 19.37 14.31 14 10855 5596 42604870
Visual acuity reduced 19.14 14.31 23 10846 17527 42592939
Blood creatine phosphokinase increased 18.28 14.31 39 10830 48299 42562167
Malignant neoplasm progression 18.01 14.31 3 10866 108397 42502069
Erysipelas 17.93 14.31 14 10855 6282 42604184
Neonatal disorder 17.90 14.31 7 10862 800 42609666
Cardio-respiratory arrest neonatal 17.67 14.31 3 10866 9 42610457
Mixed liver injury 17.38 14.31 12 10857 4462 42606004
Sensitivity to weather change 17.17 14.31 9 10860 2034 42608432
Tricuspid valve disease 17.16 14.31 5 10864 231 42610235
Eye swelling 17.07 14.31 18 10851 11902 42598564
Intra-abdominal haemorrhage 16.70 14.31 10 10859 2918 42607548
Ischaemic hepatitis 16.63 14.31 9 10860 2168 42608298
Stevens-Johnson syndrome 16.36 14.31 24 10845 22154 42588312
Skin exfoliation 16.26 14.31 34 10835 41519 42568947
Megacolon 16.22 14.31 9 10860 2276 42608190
Exposure during pregnancy 16.12 14.31 15 10854 8533 42601933
Pigmentation disorder 16.03 14.31 10 10859 3138 42607328
Rash pustular 15.95 14.31 13 10856 6202 42604264
Mycoplasma infection 15.75 14.31 6 10863 639 42609827
Hypertension neonatal 15.66 14.31 4 10865 112 42610354
Akinesia 15.56 14.31 9 10860 2463 42608003
Foetal exposure during pregnancy 15.45 14.31 36 10833 47275 42563191
Hypercapnia 15.44 14.31 12 10857 5349 42605117
Bronchoalveolar lavage abnormal 15.12 14.31 4 10865 129 42610337
Pupillary disorder 15.08 14.31 5 10864 355 42610111
Dermatitis contact 15.01 14.31 11 10858 4492 42605974
Accidental exposure to product 14.94 14.31 22 10847 20371 42590095
Motor dysfunction 14.80 14.31 14 10855 8132 42602334
Pneumonia mycoplasmal 14.64 14.31 6 10863 774 42609692
Ocular hyperaemia 14.35 14.31 19 10850 15944 42594522
Brain herniation 14.34 14.31 11 10858 4812 42605654

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug hypersensitivity 2460.13 12.40 1912 51955 452178 110083254
International normalised ratio fluctuation 255.23 12.40 90 53777 3990 110531442
Grip strength 221.96 12.40 102 53765 9039 110526393
Bloody discharge 216.70 12.40 72 53795 2661 110532771
Lyme disease 177.53 12.40 70 53797 4246 110531186
Dislocation of vertebra 176.11 12.40 156 53711 43565 110491867
Porphyria acute 175.31 12.40 111 53756 18669 110516763
Breast cancer stage III 164.83 12.40 198 53669 78919 110456513
Adjustment disorder with depressed mood 163.79 12.40 150 53717 43733 110491699
Lupus vulgaris 150.82 12.40 128 53739 33755 110501677
Maternal exposure during pregnancy 135.30 12.40 348 53519 254535 110280897
Foot deformity 134.70 12.40 141 53726 48339 110487093
Drug tolerance decreased 128.68 12.40 107 53760 27433 110507999
Autoimmune disorder 128.47 12.40 159 53708 65324 110470108
Bone erosion 123.74 12.40 132 53735 46239 110489193
X-ray abnormal 117.03 12.40 117 53750 38000 110497432
Retinitis 115.78 12.40 108 53759 32219 110503213
Exostosis 112.47 12.40 125 53742 45831 110489601
Laryngitis 108.37 12.40 118 53749 42293 110493139
Abortion spontaneous 102.99 12.40 104 53763 34178 110501254
Ear infection 100.72 12.40 138 53729 62594 110472838
Amnesia 99.82 12.40 182 53685 105226 110430206
Walking aid user 98.05 12.40 88 53779 24987 110510445
Wound infection 97.03 12.40 171 53696 96294 110439138
Seronegative arthritis 96.60 12.40 67 53800 13110 110522322
Deep vein thrombosis postoperative 93.04 12.40 129 53738 59162 110476270
Anaemia 91.76 12.40 79 53788 547007 109988425
Grip strength decreased 91.03 12.40 150 53717 80024 110455408
Sleep disorder due to a general medical condition 88.78 12.40 118 53749 51994 110483438
Death 88.62 12.40 127 53740 698742 109836690
Laboratory test abnormal 84.79 12.40 106 53761 43973 110491459
Neutropenia 83.49 12.40 39 53828 374581 110160851
Hypotension 82.66 12.40 80 53787 523769 110011663
Hepatic cirrhosis 80.13 12.40 129 53738 67497 110467935
Maternal exposure timing unspecified 78.73 12.40 72 53795 20941 110514491
Swollen joint count 77.79 12.40 50 53817 8624 110526808
Rheumatic fever 76.27 12.40 178 53689 122401 110413031
Rheumatoid factor positive 75.28 12.40 185 53682 131455 110403977
Swollen joint count increased 72.39 12.40 139 53728 83522 110451910
Lupus-like syndrome 70.46 12.40 93 53774 40699 110494733
Wheezing 69.46 12.40 277 53590 254953 110280479
Colitis ulcerative 68.75 12.40 130 53737 77233 110458199
Exposure during pregnancy 67.52 12.40 207 53660 167217 110368215
Febrile neutropenia 67.50 12.40 35 53832 316732 110218700
Drug abuse 67.23 12.40 5 53862 177406 110358026
Delirium 67.12 12.40 180 53687 134845 110400587
Visual impairment 65.61 12.40 178 53689 134250 110401182
Bursitis 65.39 12.40 174 53693 129744 110405688
Joint range of motion decreased 65.24 12.40 167 53700 121665 110413767
Frequent bowel movements 62.24 12.40 119 53748 71271 110464161
Pulmonary fibrosis 61.11 12.40 146 53721 101896 110433536
Anti-cyclic citrullinated peptide antibody 60.76 12.40 61 53806 19903 110515529
Ulcerative keratitis 59.59 12.40 34 53833 4732 110530700
Completed suicide 59.18 12.40 22 53845 242359 110293073
Road traffic accident 58.31 12.40 148 53719 107250 110428182
Product packaging issue 58.03 12.40 24 53843 1647 110533785
Pancreatitis 57.28 12.40 135 53732 93398 110442034
Type 2 diabetes mellitus 56.18 12.40 202 53665 177030 110358402
C-reactive protein abnormal 55.72 12.40 164 53703 129531 110405901
Fall 54.92 12.40 134 53733 603348 109932084
Red blood cell sedimentation rate increased 54.61 12.40 119 53748 78183 110457249
Toxicity to various agents 54.50 12.40 94 53773 480461 110054971
Malignant neoplasm progression 53.68 12.40 10 53857 174557 110360875
Hypercholesterolaemia 53.35 12.40 129 53738 90708 110444724
Duodenal ulcer perforation 53.34 12.40 199 53668 177501 110357931
Infection 53.29 12.40 330 53537 361870 110173562
Pregnancy 53.25 12.40 92 53775 50975 110484457
Feeling hot 53.10 12.40 129 53738 90977 110444455
Spondylitis 52.85 12.40 44 53823 11294 110524138
Hyphaema 52.81 12.40 20 53847 1087 110534345
Asthma 51.60 12.40 250 53617 250041 110285391
Hyponatraemia 51.08 12.40 21 53846 217632 110317800
Disease progression 50.46 12.40 28 53839 244006 110291426
Anti factor V antibody 49.04 12.40 14 53853 308 110535124
Blood cholesterol increased 48.22 12.40 198 53669 184587 110350845
Acute kidney injury 46.85 12.40 156 53711 635274 109900158
White blood cell count increased 46.01 12.40 127 53740 96715 110438717
Mobility decreased 45.29 12.40 232 53635 237190 110298242
Memory impairment 45.20 12.40 203 53664 196741 110338691
Oedema 44.19 12.40 211 53656 209765 110325667
Monocytosis 44.07 12.40 20 53847 1720 110533712
Blister 42.55 12.40 221 53646 227155 110308277
Contusion 42.42 12.40 225 53642 233136 110302296
Peripheral venous disease 41.65 12.40 112 53755 84005 110451427
Respiratory disorder 41.52 12.40 101 53766 71281 110464151
Off label use 40.75 12.40 502 53365 1499683 109035749
Osteoporosis 40.13 12.40 113 53754 87039 110448393
Haemoglobin decreased 39.16 12.40 38 53829 248689 110286743
Liver injury 39.10 12.40 161 53706 150252 110385180
Discomfort 39.01 12.40 207 53660 214500 110320932
Platelet count decreased 38.91 12.40 33 53834 230410 110305022
Sciatica 38.88 12.40 116 53751 92283 110443149
Joint dislocation 38.84 12.40 64 53803 34126 110501306
Prescribed overdose 38.81 12.40 112 53755 87469 110447963
Toxic epidermal necrolysis 38.18 12.40 85 53782 56642 110478790
Platelet count increased 37.91 12.40 55 53812 26279 110509153
Abdominal pain upper 37.71 12.40 295 53572 348816 110186616
Anti-cyclic citrullinated peptide antibody positive 37.65 12.40 182 53685 181802 110353630
Ototoxicity 37.51 12.40 24 53843 4107 110531325
Lower limb fracture 36.97 12.40 100 53767 75248 110460184
Anaphylactic reaction 36.82 12.40 131 53736 114169 110421263
Weight fluctuation 35.96 12.40 49 53818 22096 110513336
Injection site pain 35.94 12.40 21 53846 177901 110357531
Urticaria 35.86 12.40 272 53595 318585 110216847
Helicobacter infection 35.57 12.40 179 53688 181698 110353734
Live birth 34.88 12.40 93 53774 69391 110466041
Myelosuppression 34.78 12.40 3 53864 94337 110441095
Lip dry 34.22 12.40 117 53750 99966 110435466
Facet joint syndrome 33.82 12.40 114 53753 96714 110438718
Injury 33.64 12.40 173 53694 177092 110358340
Hip arthroplasty 33.56 12.40 80 53787 55733 110479699
Folliculitis 33.49 12.40 166 53701 167487 110367945
Iron deficiency 33.26 12.40 43 53824 18433 110516999
Drug interaction 32.72 12.40 380 53487 499803 110035629
Sleep disorder due to general medical condition, insomnia type 32.27 12.40 119 53748 105524 110429908
Exposure to SARS-CoV-2 31.68 12.40 19 53848 2900 110532532
Constipation 31.30 12.40 81 53786 357705 110177727
Stevens-Johnson syndrome 31.25 12.40 70 53797 46831 110488601
Rectal haemorrhage 30.14 12.40 127 53740 119706 110415726
Mass excision 30.03 12.40 10 53857 372 110535060
Suicide attempt 29.57 12.40 7 53860 103387 110432045
Cardio-respiratory arrest 29.14 12.40 10 53857 115826 110419606
Ill-defined disorder 29.01 12.40 152 53715 156701 110378731
Secretion discharge 28.73 12.40 42 53825 20202 110515230
Hypoaesthesia 28.32 12.40 255 53612 313968 110221464
Overdose 28.08 12.40 44 53823 233750 110301682
Pulmonary embolism 28.08 12.40 38 53829 214436 110320996
Arthritis 28.03 12.40 158 53709 167428 110368004
Joint stiffness 27.89 12.40 84 53783 67159 110468273
Fibromyalgia 27.84 12.40 160 53707 170749 110364683
Atrial fibrillation 27.79 12.40 43 53824 229599 110305833
Intentional overdose 27.67 12.40 15 53852 132486 110402946
Pain 27.19 12.40 316 53551 954639 109580793
Somnolence 27.05 12.40 66 53801 297383 110238049
Tarsal tunnel syndrome 26.48 12.40 10 53857 539 110534893
Drug ineffective 26.41 12.40 553 53314 1519987 109015445
Hyperoxaluria 26.31 12.40 9 53858 364 110535068
Neutrophil count decreased 26.29 12.40 13 53854 120928 110414504
Eye pain 26.11 12.40 68 53799 50031 110485401
Spinal fusion surgery 26.08 12.40 27 53840 9129 110526303
White blood cell count decreased 25.85 12.40 45 53822 229345 110306087
Pancytopenia 25.60 12.40 39 53828 209574 110325858
Pneumococcal infection 25.53 12.40 14 53853 1805 110533627
Dehydration 25.43 12.40 62 53805 279449 110255983
Purpura senile 25.38 12.40 10 53857 605 110534827
Abdominal discomfort 25.19 12.40 298 53569 393560 110141872
Muscle injury 25.05 12.40 135 53732 140672 110394760
Systemic lupus erythematosus 24.78 12.40 210 53657 254128 110281304
Rheumatoid arthritis 24.42 12.40 238 53629 299375 110236057
Blood creatinine increased 24.35 12.40 32 53835 182857 110352575
Eye inflammation 24.27 12.40 26 53841 9145 110526287
Night sweats 24.20 12.40 129 53738 133854 110401578
Knee arthroplasty 24.05 12.40 78 53789 64870 110470562
Coma 23.67 12.40 14 53853 117855 110417577
Learning disorder 23.44 12.40 10 53857 742 110534690
Necrosis ischaemic 23.43 12.40 12 53855 1347 110534085
Serum sickness-like reaction 22.99 12.40 10 53857 778 110534654
Corneal neovascularisation 22.52 12.40 7 53860 208 110535224
Obesity 22.46 12.40 112 53755 113239 110422193
Gastrointestinal disorder 22.12 12.40 197 53670 241755 110293677
Vertigo positional 21.97 12.40 17 53850 3931 110531501
Bradycardia 21.97 12.40 26 53841 155491 110379941
Cardiac failure 21.88 12.40 36 53831 187590 110347842
Syncope 21.69 12.40 41 53826 202495 110332937
Product dose omission issue 21.67 12.40 82 53785 321700 110213732
Impaired healing 21.64 12.40 167 53700 196550 110338882
Deafness permanent 21.39 12.40 10 53857 921 110534511
Disability 21.14 12.40 46 53821 30177 110505255
Stupor 21.11 12.40 23 53844 8242 110527190
Catheter site abscess 20.75 12.40 7 53860 271 110535161
Muscular weakness 20.55 12.40 198 53669 248270 110287162
Glossodynia 20.42 12.40 181 53686 221823 110313609
Deafness bilateral 20.41 12.40 14 53853 2690 110532742
Pemphigus 20.29 12.40 176 53691 214394 110321038
Caesarean section 20.10 12.40 29 53838 13788 110521644
Mucosal inflammation 19.91 12.40 11 53856 96130 110439302
Periumbilical abscess 19.83 12.40 7 53860 311 110535121
Vomiting 19.83 12.40 582 53285 910093 109625339
Forced expiratory volume decreased 19.67 12.40 28 53839 13148 110522284
COVID-19 19.54 12.40 58 53809 245002 110290430
Hand deformity 19.51 12.40 177 53690 218329 110317103
Wound 19.48 12.40 187 53680 234250 110301182
Liver disorder 19.27 12.40 127 53740 142116 110393316
Neoplasm progression 19.22 12.40 4 53863 64591 110470841
Intraocular pressure increased 19.09 12.40 25 53842 10851 110524581
Depressed level of consciousness 19.04 12.40 16 53851 112262 110423170
Osteoarthritis 18.97 12.40 153 53714 182470 110352962
Gait disturbance 18.89 12.40 213 53654 277995 110257437
Blood glucose increased 18.88 12.40 22 53845 132474 110402958
Torsade de pointes 18.87 12.40 37 53830 22563 110512869
Sleep disorder 18.81 12.40 163 53704 198481 110336951
Myoglobinuria 18.76 12.40 10 53857 1218 110534214
Benign laryngeal neoplasm 18.74 12.40 4 53863 24 110535408
Hypokalaemia 18.61 12.40 38 53829 182410 110353022
Dyspepsia 18.24 12.40 157 53710 190808 110344624
Measles 17.91 12.40 8 53859 663 110534769
Cerebrovascular accident 17.45 12.40 39 53828 181245 110354187
Injection site reaction 17.30 12.40 11 53856 89059 110446373
Ascites 17.30 12.40 12 53855 92796 110442636
Irritable bowel syndrome 17.28 12.40 138 53729 164077 110371355
Urinary tract infection 17.23 12.40 91 53776 326191 110209241
Pneumonia streptococcal 17.22 12.40 14 53853 3475 110531957
Coagulation time prolonged 17.20 12.40 13 53854 2904 110532528
Beta haemolytic streptococcal infection 16.99 12.40 13 53854 2958 110532474
Intentional product misuse 16.94 12.40 24 53843 132880 110402552
Transaminases increased 16.78 12.40 5 53862 63385 110472047
Resorption bone increased 16.69 12.40 10 53857 1524 110533908
Cardiac failure congestive 16.67 12.40 30 53837 150970 110384462
Ergot poisoning 16.65 12.40 5 53862 132 110535300
Dysphoria 16.62 12.40 18 53849 6410 110529022
Anxiety 16.61 12.40 248 53619 344830 110190602
Bronchial obstruction 16.58 12.40 13 53854 3066 110532366
Pleural effusion 16.49 12.40 39 53828 177670 110357762
Flushing 16.48 12.40 16 53851 104720 110430712
Heart rate decreased 16.38 12.40 10 53857 82746 110452686
Pericarditis 16.37 12.40 171 53696 218943 110316489
Lip swelling 16.25 12.40 58 53809 50609 110484823
Orthostatic hypotension 16.18 12.40 6 53861 66243 110469189
SARS-CoV-2 test positive 15.71 12.40 29 53838 16906 110518526
Myocardial infarction 15.65 12.40 45 53822 192038 110343394
Amniotic cavity infection 15.61 12.40 8 53859 899 110534533
Vaginal lesion 15.24 12.40 6 53861 362 110535070
Corneal perforation 15.22 12.40 8 53859 948 110534484
Staphylococcal infection 15.22 12.40 71 53796 69873 110465559
Rash 15.05 12.40 514 53353 820450 109714982
Urticarial vasculitis 14.98 12.40 8 53859 978 110534454
Hyperkalaemia 14.97 12.40 27 53840 135769 110399663
Crystal nephropathy 14.94 12.40 10 53857 1846 110533586
Rhabdomyolysis 14.82 12.40 105 53762 120296 110415136
Lactic acidosis 14.81 12.40 14 53853 92797 110442635
Sepsis 14.78 12.40 96 53771 327250 110208182
Cytokine release syndrome 14.62 12.40 8 53859 70298 110465134
Neuropathy peripheral 14.60 12.40 42 53825 179235 110356197
Hyperglycaemia 14.58 12.40 12 53855 85078 110450354
Respiratory acidosis 14.53 12.40 25 53842 13801 110521631
Arthropathy 14.37 12.40 208 53659 287314 110248118
Pharyngeal swelling 14.31 12.40 23 53844 12009 110523423
Oculogyric crisis 14.10 12.40 13 53854 3819 110531613
Hypomagnesaemia 13.87 12.40 6 53861 60364 110475068
Pharyngeal oedema 13.84 12.40 27 53840 16401 110519031
Premature rupture of membranes 13.80 12.40 14 53853 4623 110530809
Oligohydramnios 13.64 12.40 13 53854 3981 110531451
Pathogen resistance 13.64 12.40 28 53839 17644 110517788
Symblepharon 13.56 12.40 6 53861 486 110534946
Pancreatic pseudocyst 13.51 12.40 9 53858 1649 110533783
Economic problem 13.27 12.40 13 53854 4118 110531314
Pneumonia aspiration 13.26 12.40 12 53855 81221 110454211
Encephalopathy 13.20 12.40 12 53855 81043 110454389
Anal candidiasis 13.19 12.40 3 53864 25 110535407
Dysgeusia 13.11 12.40 9 53858 69976 110465456
Cardiac arrest neonatal 13.09 12.40 3 53864 26 110535406
Sedation 13.00 12.40 9 53858 69674 110465758
Mixed liver injury 12.90 12.40 22 53845 12057 110523375
Injection site swelling 12.89 12.40 7 53860 61783 110473649
Haemorrhagic diathesis 12.78 12.40 17 53850 7491 110527941
Myasthenia gravis crisis 12.77 12.40 9 53858 1805 110533627
Product dispensing error 12.74 12.40 26 53841 16319 110519113
Cardiogenic shock 12.71 12.40 6 53861 57332 110478100
Haematochezia 12.70 12.40 23 53844 115501 110419931
Morbid thoughts 12.70 12.40 7 53860 912 110534520
Cerebral haemorrhage 12.65 12.40 8 53859 64960 110470472
Dry mouth 12.64 12.40 151 53716 199797 110335635
Abdominal rigidity 12.61 12.40 12 53855 3668 110531764
Pancreatic mass 12.59 12.40 9 53858 1846 110533586
Respiratory failure 12.55 12.40 58 53809 215274 110320158
Corneal deposits 12.46 12.40 6 53861 590 110534842

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA CS M0028311 Macrolides
FDA PE N0000009982 Decreased Sebaceous Gland Activity
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D011500 Protein Synthesis Inhibitors
FDA EPC N0000175877 Macrolide
FDA EPC N0000175935 Macrolide Antimicrobial
CHEBI has role CHEBI:35703 xenobiotic
CHEBI has role CHEBI:76969 bacterial metabolite
CHEBI has role CHEBI:78298 environmental contaminant

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Meningitis indication 7180009 DOID:9471
Bacterial septicemia indication 10001005 DOID:0040085
Infection of skin AND/OR subcutaneous tissue indication 19824006
Bacterial pneumonia indication 53084003 DOID:874
Urinary tract infectious disease indication 68566005
Hepatic coma indication 72836002 DOID:12550
Cholangitis indication 82403002 DOID:9446
Infection of bone indication 111253001
Infectious disease of abdomen indication 128070006
Infectious disorder of joint indication 363162000
Preoperative Bowel Preparation indication
Burn Wound Infections indication
Acute tuberculosis off-label use 25629007
Pulmonary tuberculosis off-label use 154283005 DOID:2957
Hypocalcemia contraindication 5291005
Parkinsonism contraindication 32798002
Dehydration contraindication 34095006
Tinnitus contraindication 60862001
Kidney disease contraindication 90708001 DOID:557
Myasthenia gravis contraindication 91637004 DOID:437
Pregnancy, function contraindication 289908002
Vertigo contraindication 399153001
Infant Botulism contraindication
Disorder of the 8th Cranial Nerve contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.61 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017592 VUID
N0000145973 NUI
4017592 VANDF
4017594 VANDF
C0014810 UMLSCUI
CHEBI:31555 CHEBI
CHEMBL1200688 ChEMBL_ID
D015643 MESH_DESCRIPTOR_UI
1014KSJ86F UNII
443953 PUBCHEM_CID
151373 RXNORM
33314 MMSL
42396 MMSL
4543 MMSL
4675 MMSL
4677 MMSL
4799 MMSL
72164 MMSL
d00046 MMSL
002755 NDDF
002757 NDDF
12578001 SNOMEDCT_US
30427009 SNOMEDCT_US
372694001 SNOMEDCT_US
C0014806 UMLSCUI
DB00199 DRUGBANK_ID
12560 PUBCHEM_CID
39 INN_ID
D004917 MESH_DESCRIPTOR_UI
CHEBI:42355 CHEBI

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
ERYTHROMYCIN ETHYLSUCCINATE AND SULFISOXAZOLE ACETYL HUMAN PRESCRIPTION DRUG LABEL 2 21695-690 GRANULE, FOR SUSPENSION 200 mg ORAL ANDA 26 sections
E.E.S 400 HUMAN PRESCRIPTION DRUG LABEL 1 24338-100 TABLET 400 mg ORAL ANDA 27 sections
ERYTHROMYCIN ETHYLSUCCINATE HUMAN PRESCRIPTION DRUG LABEL 1 24338-110 TABLET 400 mg ORAL ANDA 26 sections
Ery-Ped HUMAN PRESCRIPTION DRUG LABEL 1 24338-130 SUSPENSION 400 mg ORAL NDA 27 sections
Ery-Ped HUMAN PRESCRIPTION DRUG LABEL 1 24338-132 SUSPENSION 200 mg ORAL NDA 27 sections
E.E.S HUMAN PRESCRIPTION DRUG LABEL 1 24338-134 GRANULE, FOR SUSPENSION 200 mg ORAL NDA 27 sections
E.E.S HUMAN PRESCRIPTION DRUG LABEL 1 24338-136 GRANULE, FOR SUSPENSION 200 mg ORAL NDA 27 sections
ERYTHROMYCIN ETHYLSUCCINATE HUMAN PRESCRIPTION DRUG LABEL 1 52536-130 SUSPENSION 400 mg ORAL NDA 27 sections
ERYTHROMYCIN ETHYLSUCCINATE HUMAN PRESCRIPTION DRUG LABEL 1 52536-132 SUSPENSION 200 mg ORAL NDA 27 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 52536-134 GRANULE, FOR SUSPENSION 200 mg ORAL NDA 28 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 52536-136 GRANULE, FOR SUSPENSION 200 mg ORAL NDA 28 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 54868-0018 TABLET 400 mg ORAL ANDA 13 sections
ERYTHROMYCIN ETHYLSUCCINATE AND SULFISOXAZOLE ACETYL HUMAN PRESCRIPTION DRUG LABEL 2 54868-0971 GRANULE, FOR SUSPENSION 200 mg ORAL ANDA 26 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 60219-1503 SUSPENSION 200 mg ORAL ANDA 19 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 60219-1504 SUSPENSION 400 mg ORAL ANDA 19 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 62559-440 GRANULE, FOR SUSPENSION 200 mg ORAL ANDA 23 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 62559-630 GRANULE, FOR SUSPENSION 200 mg ORAL ANDA 22 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 62559-631 GRANULE, FOR SUSPENSION 400 mg ORAL ANDA 22 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 69238-1503 SUSPENSION 200 mg ORAL ANDA 19 sections
Erythromycin Ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 69238-1504 SUSPENSION 400 mg ORAL ANDA 19 sections
E.E.S400 HUMAN PRESCRIPTION DRUG LABEL 1 70518-4681 TABLET 400 mg ORAL ANDA 26 sections
Erythromycin ethylsuccinate Human Prescription Drug Label 1 71209-102 FOR SUSPENSION 200 mg ORAL ANDA 22 sections
Erythromycin ethylsuccinate Human Prescription Drug Label 1 71209-103 FOR SUSPENSION 400 mg ORAL ANDA 22 sections
Erythromycin ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 72162-2657 FOR SUSPENSION 200 mg ORAL ANDA 23 sections
Erythromycin ethylsuccinate HUMAN PRESCRIPTION DRUG LABEL 1 72162-2658 FOR SUSPENSION 400 mg ORAL ANDA 23 sections
Erythromycin Ethylsuccinate Human Prescription Drug Label 1 75834-294 SUSPENSION 400 mg ORAL ANDA 20 sections
Erythromycin Ethylsuccinate Human Prescription Drug Label 1 75834-295 SUSPENSION 200 mg ORAL ANDA 20 sections
E.E.S HUMAN PRESCRIPTION DRUG LABEL 1 80005-152 GRANULE, FOR SUSPENSION 200 mg ORAL NDA 27 sections
E.E.S HUMAN PRESCRIPTION DRUG LABEL 1 80005-153 GRANULE, FOR SUSPENSION 200 mg ORAL NDA 27 sections
Ery-Ped HUMAN PRESCRIPTION DRUG LABEL 1 80005-155 SUSPENSION 400 mg ORAL NDA 27 sections