epirizole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1029 18694-40-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methopyrimazole
  • epirizole
  • mepirizole
  • mebron
4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine. A pyrimidinyl pyrazole with antipyretic, analgesic, and anti-inflammatory activity.
  • Molecular weight: 234.26
  • Formula: C11H14N4O2
  • CLOGP: 2.35
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 0
  • TPSA: 62.06
  • ALOGS: -2.32
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.31 Basic
pKa2 1.64 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01394 KEGG_DRUG
C0014581 UMLSCUI
CHEBI:31545 CHEBI
CHEMBL1411693 ChEMBL_ID
DB08991 DRUGBANK_ID
D004840 MESH_DESCRIPTOR_UI
3242 PUBCHEM_CID
2929 INN_ID
3B46O2FH8I UNII

Pharmaceutical products:

None