acetylcarnitine indications/contra

Stem definitionDrug idCAS RN
64 3040-38-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acetylcarnitine
  • L-Acetylcarnitine
  • levocarnitine acetyl
  • O-Acetylcarnitine
An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.
  • Molecular weight: 203.24
  • Formula: C9H17NO4
  • CLOGP: -6.88
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 0
  • TPSA: 66.43
  • ALOGS: -2.86
  • ROTB: 6

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC N06BX12 NERVOUS SYSTEM
PSYCHOANALEPTICS
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Other psychostimulants and nootropics
MeSH PA D002491 Central Nervous System Agents
MeSH PA D006133 Growth Substances
MeSH PA D018977 Micronutrients
MeSH PA D018697 Nootropic Agents
MeSH PA D014803 Vitamin B Complex
MeSH PA D014815 Vitamins

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Senile dementia indication 15662003
Alzheimer's disease indication 26929004 DOID:10652
Kidney disease contraindication 90708001 DOID:2527
Seizure disorder contraindication 128613002 DOID:1826

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.41 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
4029065 VUID
N0000179824 NUI
C0001040 UMLSCUI
6DH1W9VH8Q UNII
1 PUBCHEM_CID
4029065 VANDF
N0000166509 NDFRT
N0000179824 NDFRT
193 RXNORM
006988 NDDF
CHEBI:73024 CHEBI
CHEMBL1358846 ChEMBL_ID
DB08842 DRUGBANK_ID
CHEMBL1697733 ChEMBL_ID
D000108 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None