oxiracetam 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
amide type nootrope agents, piracetam derivatives 2021 62613-82-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxiracetam
  • hydroxypiracetam
  • neuromet
  • Molecular weight: 158.16
  • Formula: C6H10N2O3
  • CLOGP: -1.20
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 83.63
  • ALOGS: 0.48
  • ROTB: 2

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 75 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution) 0.55 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 1.80 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 7.50 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N06BX07 NERVOUS SYSTEM
PSYCHOANALEPTICS
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Other psychostimulants and nootropics
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018697 Nootropic Agents
MeSH PA D011619 Psychotropic Drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.37 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07346 KEGG_DRUG
C0069772 UMLSCUI
CHEBI:134788 CHEBI
CHEMBL36633 ChEMBL_ID
DB13601 DRUGBANK_ID
4626 PUBCHEM_CID
4762 INN_ID
C040619 MESH_SUPPLEMENTAL_RECORD_UI
P7U817352G UNII
32645 RXNORM
008270 NDDF

Pharmaceutical products:

None