pleconaril 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antivirals 4690 153168-05-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pleconaril
  • picovir
  • Molecular weight: 381.36
  • Formula: C18H18F3N3O3
  • CLOGP: 4.89
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 0
  • TPSA: 74.18
  • ALOGS: -4.24
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J05AX06 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIVIRALS FOR SYSTEMIC USE
DIRECT ACTING ANTIVIRALS
Other antivirals
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000998 Antiviral Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Nuclear receptor subfamily 1 group I member 2 Nuclear hormone receptor EC50 6.60 CHEMBL
Protease Enzyme EC50 7.24 CHEMBL
Genome polyprotein Unclassified EC50 8.40 CHEMBL

External reference:

IDSource
D05528 KEGG_DRUG
C0759032 UMLSCUI
W11 PDB_CHEM_ID
CHEMBL29609 ChEMBL_ID
DB05105 DRUGBANK_ID
C115201 MESH_SUPPLEMENTAL_RECORD_UI
7617 INN_ID
9H4570Q89D UNII
1684 PUBCHEM_CID

Pharmaceutical products:

None