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bucillamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 414 | 65002-17-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Lymphoproliferative disorder | 173.89 | 45.88 | 30 | 699 | 4232 | 90623486 |
| Diffuse large B-cell lymphoma | 71.26 | 45.88 | 16 | 713 | 8629 | 90619089 |
| Interstitial lung disease | 68.67 | 45.88 | 25 | 704 | 76380 | 90551338 |
| Epstein-Barr virus associated lymphoproliferative disorder | 64.04 | 45.88 | 12 | 717 | 2655 | 90625063 |
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Lymphoproliferative disorder | 75.71 | 70.40 | 13 | 176 | 3294 | 42617852 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Lymphoproliferative disorder | 233.68 | 42.01 | 43 | 1038 | 7175 | 110581043 |
| Interstitial lung disease | 93.86 | 42.01 | 39 | 1042 | 139295 | 110448923 |
| Diffuse large B-cell lymphoma | 82.39 | 42.01 | 21 | 1060 | 15877 | 110572341 |
| Epstein-Barr virus associated lymphoproliferative disorder | 77.47 | 42.01 | 16 | 1065 | 4786 | 110583432 |
| Epstein-Barr virus infection | 42.67 | 42.01 | 13 | 1068 | 18725 | 110569493 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | M01CC02 | MUSCULO-SKELETAL SYSTEM ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS SPECIFIC ANTIRHEUMATIC AGENTS Penicillamine and similar agents |
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| MeSH PA | D000975 | Antioxidants |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D018501 | Antirheumatic Agents |
| MeSH PA | D018689 | Sensory System Agents |
| MeSH PA | D018712 | Analgesics, Non-Narcotic |
| MeSH PA | D020011 | Protective Agents |
Related Drugs by ATC class:
M01CC Penicillamine and similar agents 1 drug
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.2 | acidic |
| pKa2 | 8.46 | acidic |
| pKa3 | 9.51 | acidic |
| pKa4 | 13.13 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01809 | KEGG_DRUG |
| C0073917 | UMLSCUI |
| CHEBI:31312 | CHEBI |
| CHEMBL80830 | ChEMBL_ID |
| DB12160 | DRUGBANK_ID |
| 656604 | PUBCHEM_CID |
| C026535 | MESH_SUPPLEMENTAL_RECORD_UI |
| 5683 | INN_ID |
| R80LRA5WTF | UNII |
Pharmaceutical products:
None