bezitramide indications/contra

Stem definitionDrug idCAS RN
363 15301-48-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • R-4845
  • bezitramide monohydrochloride
  • bezitramide hydrochloride
  • bezitramide HCl
  • bezitramide
  • benzitramide
  • burgodin
  • Molecular weight: 492.62
  • Formula: C31H32N4O2
  • CLOGP: 5.28
  • LIPINSKI: 1
  • HAC: 6
  • HDO: 0
  • TPSA: 67.65
  • ALOGS: -4.87
  • ROTB: 7

Drug dosage:

DoseUnitRoute
15 mg O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

scroll-->
SourceCodeDescription
ATC N02AC05 NERVOUS SYSTEM
ANALGESICS
OPIOIDS
Diphenylpropylamine derivatives
MeSH PA D000700 Analgesics
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

scroll-->
Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.65 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

scroll-->
IDSource
D07289 KEGG_DRUG
3KXW0Y310I UNII
1942 INN_ID
61791 PUBCHEM_CID
C004461 MESH_SUPPLEMENTAL_RECORD_UI
DB01459 DRUGBANK_ID
CHEMBL2104149 ChEMBL_ID
CHEBI:135794 CHEBI

Pharmaceutical products:

None